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nox from Streptococcus pneumoniae D39

Victor ID 3086
Gene Name nox from Streptococcus pneumoniae D39
Sequence Strain (Species/Organism) Streptococcus pneumoniae D39
NCBI Gene ID 4442449
NCBI Protein GI 116516669
Locus Tag SPD_1298
Protein Accession YP_816764.1
Other Database IDs UniProtKB-ID: Q04JN4_STRP2
UniRef100: UniRef100_B2IQT6
UniRef90: UniRef90_B2IQT6
UniRef50: UniRef50_A2RIB7
UniParc: UPI00000B9663
EMBL: CP000410
EMBL-CDS: ABJ54965.1
RefSeq_NT: NC_008533.1
EnsemblGenome: EBSTRG00000019110.
EnsemblGenome_TRS: EBSTRT00000019110
EnsemblGenome_PRO: EBSTRP00000018350
GenomeReviews: CP000410_GR
KEGG: spd:SPD_1298
eggNOG: COG0446
HOGENOM: HBG535576
OMA: FFFQPHF
ProtClustDB: CLSK877163
Taxonomy ID 373153
Gene Starting Position 1316925
Gene Ending Position 1318304
Gene Strand (Orientation) -
Protein Name NADH oxidase
DNA Sequence 
>gi|116515308:1316925-1318304 Streptococcus pneumoniae D39, complete genome
TTTATTTTTCAGCCGTAAGGGCAGCCATTGTGATGTAGTTGTATGGTTTGTTGAAGTGTGGCAAGAAGAA
GAGGTCTGTCAATGCCAATTTATCAATTGTCACATGCTCTTGGATAGCAAGTGAGAACATGTGGATTCCC
ATGCTAATTGCAATATCATGTGAAACCATTTGGGCACCAAGAATTTCACGGCTATCTTTGTCAAAGACAA
TCTTAATTGCTACTTCATGGTTGTCATGTTTCATGAATTCTGGTTTTTGAAGATCGTTAAAGCCTGTTTC
AGTTGCGTTGTAACCAGCAGCTTTCGCTTTTTCAAGAGTCAAACCAGTTGAAACCATGTGAAGACCGTAG
ATTGAGATACCATTTGAACCTTGAACACCGATTCCTTCCAATTCATGTCCACAAGCGTTGTAGGCACCAA
CGATACCAGTGCGAACAGCATTTGAAGCAAGAGCGATATAGCTTGTATCTTTACGAGCATTGTCATAAAC
AGTCGCACAGTCACCAACAGCGTAAACGCCTGGGATAGATGTTTCTTGTTTCTTGTCTACAAGGAAGGCA
CCGTTGCGGAAGAGTTCGATCTTACCATCTGCAAGGGCTGTGTTTGGACGGAAACCAACTGCAAGGATAA
CCATATCCACGTCAAAGCTTTCTTTGTCAGTAATCAAGCGTTCAACTTTACCGTCACCTTCGATTGCTTT
AACAGTTTGACCTAGAGCCAAGCGGATGTTGTGATCTTCCAAGTTCTTCGCCATCATTTGTGTGAAGTCT
TTGTCATAGTAACCGTTCAAGACAGTATCAACGATATCAACAAGGACAACTTCTTTTCCAAGACGTTCAA
AGGCTTCAGCAAGTTCAACACCGATGTAACCACCACCAACAACGGCGATACGGTCGAGGTGTTGGCTCTT
GTCAGAAAGTTTATTGATAACTTCTTCAGCATTTTGGTACAATTTCACGAATTGTACGTTTTCAAGAGTT
GCTTTAAATTCGCGGTTTCCTTTAACAATTTCAACACCTTCGATTGGTGGCAAGATTGGTGTAGAACCTG
TAGCGAAAATCAATTTTTCGTATGATTCTTTGTGCTCTTTTCCTTCAACTTCCGCTGTAACTACTTTGTT
ATCATAGTCGATTGAAAGAACAGGTGAGTTCATGTAAACTTTAGCACCTTTAGCTTCCAATTTTTCTTTA
TCAGAATAGAACAAGCCTTCAGCACCGTCAATTTGTTCACCAATCCAAAGAGCCATTCCACATCCTAGGA
AAGAGATGTTAGAGTTTTGGTCAAATACAACAATTTCGTTCTCATTTCCAAAATTATCCAACATGGTATT
GATACATGCTGTACCAGCGTGGTTAGCACCGACTACAACGATTTTACTCA
Protein Sequence 
>gi|116516669|ref|YP_816764.1| NADH oxidase [Streptococcus pneumoniae D39] MSKIVVVGANHAGTACINTMLDNFGNENEIVVFDQNSNISFLGCGMALWIGEQIDGAEGLFYSDKEKLEAKGAKVYMNSPVLSIDYDNKVVTAEVEGKEHKESYEKLIFATGSTPILPPIEGVEIVKGNREFKATLENVQFVKLYQNAEEVINKLSDKSQHLDRIAVVGGGYIGVELAEAFERLGKEVVLVDIVDTVLNGYYDKDFTQMMAKNLEDHNIRLALGQTVKAIEGDGKVERLITDKESFDVDMVILAVGFRPNTALADGKIELFRNGAFLVDKKQETSIPGVYAVGDCATVYDNARKDTSYIALASNAVRTGIVGAYNACGHELEGIGVQGSNGISIYGLHMVSTGLTLEKAKAAGYNATETGFNDLQKPEFMKHDNHEVAIKIVFDKDSREILGAQMVSHDIAISMGIHMFSLAIQEHVTIDKLALTDLFFLPHFNKPYNYITMAALTAEK
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: nox mutant is attenuated in mice (Yu et al., 2001).
COG COG0446R, under R: General function prediction only
References
Yu et al., 2001: Yu J, Bryant AP, Marra A, Lonetto MA, Ingraham KA, Chalker AF, Holmes DJ, Holden D, Rosenberg M, McDevitt D. Characterization of the Streptococcus pneumoniae NADH oxidase that is required for infection. Microbiology (Reading, England). 2001; 147(Pt 2); 431-438. [PubMed: 11158360].