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cbpD from Streptococcus pneumoniae D39

Victor ID 3085
Gene Name cbpD from Streptococcus pneumoniae D39
Sequence Strain (Species/Organism) Streptococcus pneumoniae D39
NCBI Gene ID 4442443
NCBI Protein GI 116516664
Locus Tag SPD_2028
Protein Accession YP_817413.1
Other Database IDs UniProtKB-ID: Q04HX5_STRP2
UniRef100: UniRef100_Q04HX5
UniRef90: UniRef90_B1IA13
UniRef50: UniRef50_Q8DMZ4
UniParc: UPI0000E5338D
EMBL: CP000410
EMBL-CDS: ABJ54960.1
RefSeq_NT: NC_008533.1
EnsemblGenome: EBSTRG00000019287.
EnsemblGenome_TRS: EBSTRT00000019287
EnsemblGenome_PRO: EBSTRP00000018527
GenomeReviews: CP000410_GR
KEGG: spd:SPD_2028
eggNOG: COG3942
HOGENOM: HBG702133
OMA: RVIKANT
ProtClustDB: CLSK803921
Taxonomy ID 373153
Gene Starting Position 2006511
Gene Ending Position 2007857
Gene Strand (Orientation) -
Protein Name choline binding protein D
DNA Sequence 
>gi|116515308:2006511-2007857 Streptococcus pneumoniae D39, complete genome
TCTATACTCGTTCTCCATCACTGTTTACTCTGTAGCCATCCACCGTCGTATTAATAGCTAAGGCGCCTGA
AGAGTAAGAATAATACCACTCACCAGAGACCTGGTACCAGCCTGTTTTCATTGCCCCTGAACTACCCAGA
TAATACCACGAGCCATTCTCCTTTAACCATCCTGTCTGCATTTCACCAGATAATTTCAAATAATACCAGC
TAGAACCGTCTTTCAGCCATCCTGTTGATTTAGAACCATTTGATTTGAAATGATACCAACTACCATTTAT
TTTCTTCCAACCGACAGTTGAACTATTATTGGATCCATAGCTAGAGATATTTCCTGATTGATTCTGATAA
TTTTGTGAAGAAGTCACTCCCTCTAGCTGTATATAGCGACGACTTCCGTTATAAGCCGTATAACTCAACC
ACTTATAGCCGTCTTTTTCAAGTATCTGATCATAATGAACCTTCTCTCCAGGATAATAGTAATCAATCAC
AGTTGCACTAACTAGGGGTTCAGTTTTAATAGCAGACTTGATCTTAAAATAATGAGTTCCTCCTGTTGAA
GAAAGAACAGAATTACCTAGAGGATTTTTATTCACAGCCTCCAATTGAACATAACGATAGCTTCCATTAT
AGGCAGTATAACTCAACCACTTATAGCCGTCTTTTTCAAGTATCTGATCATAATGAACCTTCTCCCCAGG
ATAATAGTAATCAATCACAGTTGCACTAACTAGGGGTTCAGTTTTAATAGCAGACTTGGTCTTAAAATAA
TGAGTTCCGCCTGTTGAAGCTGAGGATTGACTATTCCCAACACTGCCACTATCCAAATCTTTAAAATGAA
TAAATCCTGTCATCGTGTTTGCTTTTATAACTCGTTTATTATAGGATTCTGTATAACCATAGTTATATTC
CTCAATCTCAATCTGATCTCCCATTACATTTGACACCCAGGCAACATGACCATAAGTTCCTGCAGTAGAC
CAAGTAATGGAACCAATCGTCGGTGTATTATCTACACGATAACCTTCCCGACGAGCACGATGTCCCCATT
CATTCGCATTTCCATAAGCTGCCGGAATTTCAAAACCATTGACATTACTCAAACGAAAGGCTACAAAAGA
AGTACACTGACGAGAATACATGCGCCACTGATCAATCTCCTGGCTCCCATTTTTATAATAAGCAGGATAA
TCATCCCCACGCGCAATCGATCCATTTCCTCTGGAATAGGCATGGACACTATCACCAGCTGCTAGCATCA
ATCCTACTACTAAAAAAGGAACAAGCTTTTTAACTGACATCTTCAAGTAATAACTTGTTCCTCTTGCTAT
AAACGGTAAAATTTTCA
Protein Sequence 
>gi|116516664|ref|YP_817413.1| choline binding protein D [Streptococcus pneumoniae D39] MKILPFIARGTSYYLKMSVKKLVPFLVVGLMLAAGDSVHAYSRGNGSIARGDDYPAYYKNGSQEIDQWRMYSRQCTSFVAFRLSNVNGFEIPAAYGNANEWGHRARREGYRVDNTPTIGSITWSTAGTYGHVAWVSNVMGDQIEIEEYNYGYTESYNKRVIKANTMTGFIHFKDLDSGSVGNSQSSASTGGTHYFKTKSAIKTEPLVSATVIDYYYPGEKVHYDQILEKDGYKWLSYTAYNGSYRYVQLEAVNKNPLGNSVLSSTGGTHYFKIKSAIKTEPLVSATVIDYYYPGEKVHYDQILEKDGYKWLSYTAYNGSRRYIQLEGVTSSQNYQNQSGNISSYGSNNSSTVGWKKINGSWYHFKSNGSKSTGWLKDGSSWYYLKLSGEMQTGWLKENGSWYYLGSSGAMKTGWYQVSGEWYYSYSSGALAINTTVDGYRVNSDGERV
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: cbpD has reduced colonization of nasopharynx of rats compared to the wild type (Gosink et al., 2000).
COG COG3942R, under R: General function prediction only
References
Gosink et al., 2000: Gosink KK, Mann ER, Guglielmo C, Tuomanen EI, Masure HR. Role of novel choline binding proteins in virulence of Streptococcus pneumoniae. Infection and immunity. 2000; 68(10); 5690-5695. [PubMed: 10992472].