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pepC

Victor ID 3079
Gene Name pepC
Sequence Strain (Species/Organism) Streptococcus pneumoniae D39
NCBI Gene ID 4442061
NCBI Protein GI 116516913
Locus Tag SPD_0261
Protein Accession YP_815779.1
Other Database IDs UniProtKB-ID: Q04MG9_STRP2
UniRef100: UniRef100_C1CB55
UniRef90: UniRef90_C1CB55
UniRef50: UniRef50_Q10744
UniParc: UPI00000C9C8B
EMBL: CP000410
EMBL-CDS: ABJ55209.1
RefSeq_NT: NC_008533.1
MEROPS: C01.086
EnsemblGenome: EBSTRG00000019095.
EnsemblGenome_TRS: EBSTRT00000019095
EnsemblGenome_PRO: EBSTRP00000018335
GenomeReviews: CP000410_GR
KEGG: spd:SPD_0261
eggNOG: COG3579
HOGENOM: HBG350935
OMA: LSQNYTN
ProtClustDB: CLSK876938
Taxonomy ID 373153
Gene Starting Position 259029
Gene Ending Position 260363
Gene Strand (Orientation) +
Protein Name aminopeptidase C
DNA Sequence 
>gi|116515308:259029-260363 Streptococcus pneumoniae D39, complete genome
TATGAACGCGATTCAAGAATCATTTACTGATAAACTATTTGCCAACTATGAAGCAAATGTAAAATACCAA
GCGATTGAAAATGCTGCCAGCCACAACGGAATTTTTGCAGCTCTGGAACGTCGCCAAAGCCATGTAGACA
ACACACCTGTTTTCTCATTGGATTTAACCAAGGACAAGGTCACTAACCAGAAAGCGTCTGGTCGTTGCTG
GATGTTTGCGGCTCTCAACACCTTCCGCCACAAACTCATCTCGCAATACAAATTGGAGAACTTTGAGTTG
TCACAAGCCCACACTTTCTTCTGGGATAAGTATGAGAAATCAAACTGGTTCTTGGAGCAAGTCATTGCGA
CTTCAGACCAAGAATTGACTAGCCGCAAGGTTAGCTTCTTACTCCAAACACCTCAACAAGATGGCGGTCA
ATGGGATATGGTCGTTTCCCTCTTTGAAAAATACGGTGTCGTGCCTAAGTCAGTTTATCCTGAGTCTGTT
TCATCTAGCAGCAGTCGTGAGCTAAATGCGATCCTTAATAAATTGCTTCGTCAAGATGCTCAAATCTTGC
GTGACTTGCTTGTTTCTGGTGCAGATCAAGCGACTGTTCAAGCTAAGAAAGAAGACCTCTTGCAAGAAAT
CTTTAACTTTCTTGCTATGTCATTGGGACTTCCACCACGCAAGTTTGACTTTGCTTATCGCGATAAAGAT
AACAACTACAAAAGTGAAAAAGGAATCACACCACAAGAGTTTTACAAGAAATATGTCAATCTTCCTTTAG
AAGACTACGTTTCTGTTATCAATGCTCCAACTGCTGATAAACCTTACGGAAAATCTTACACAGTTGAGAT
GTTGGGGAATGTGGTTGGTAGCCGTGCAGTTCGCTACATCAACGTTCCAATGGAGCGCTTGAAAGAATTG
GCGATTGCCCAAATGCAAGCAGGTGAGACTGTTTGGTTTGGTTCTGATGTCGGCCAGCTCAGCAACCGTA
AGGCTGGCATCCTTGCGACAGATGTTTATGACTTTGAATCAAGCATGGACATTAAACTTACTCAAGACAA
GGCTGGACGTTTGGACTATAGTGAAAGCTTGATGACCCACGCCATGGTCTTGACAGGTGTTGACTTGGAC
GAAAATGGTAAATCAACCAAGTGGAAGGTTGAAAACTCATGGGGAGACAAGGTCGGTACAGATGGTTACT
TTGTTGCCTCAGACGCTTGGATGGACGAATACACATACCAAATCGTTGTTCGTAAGGAATTGCTGACAGC
AGAAGAACAAGCTGCCTATGGAGCAGAACCAATCGTACTTGCACCATGGGATCCAATGGGAGCCTTGGCT
GAATA
Protein Sequence 
>gi|116516913|ref|YP_815779.1| aminopeptidase C [Streptococcus pneumoniae D39] MNAIQESFTDKLFANYEANVKYQAIENAASHNGIFAALERRQSHVDNTPVFSLDLTKDKVTNQKASGRCWMFAALNTFRHKLISQYKLENFELSQAHTFFWDKYEKSNWFLEQVIATSDQELTSRKVSFLLQTPQQDGGQWDMVVSLFEKYGVVPKSVYPESVSSSSSRELNAILNKLLRQDAQILRDLLVSGADQATVQAKKEDLLQEIFNFLAMSLGLPPRKFDFAYRDKDNNYKSEKGITPQEFYKKYVNLPLEDYVSVINAPTADKPYGKSYTVEMLGNVVGSRAVRYINVPMERLKELAIAQMQAGETVWFGSDVGQLSNRKAGILATDVYDFESSMDIKLTQDKAGRLDYSESLMTHAMVLTGVDLDENGKSTKWKVENSWGDKVGTDGYFVASDAWMDEYTYQIVVRKELLTAEEQAAYGAEPIVLAPWDPMGALAE
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: a pepC mutant was attenuated in a murine model (Lau et al., 2001)
COG COG3579E, under E: Amino acid transport and metabolism
References
Lau et al., 2001: Lau GW, Haataja S, Lonetto M, Kensit SE, Marra A, Bryant AP, McDevitt D, Morrison DA, Holden DW. A functional genomic analysis of type 3 Streptococcus pneumoniae virulence. Molecular microbiology. 2001; 40(3); 555-571. [PubMed: 11359563].