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lytB from Streptococcus pneumoniae D39

Victor ID 3078
Gene Name lytB from Streptococcus pneumoniae D39
Sequence Strain (Species/Organism) Streptococcus pneumoniae D39
NCBI Gene ID 4441884
NCBI Protein GI 116517112
Locus Tag SPD_0853
Protein Accession YP_816335.1
Other Database IDs UniProtKB-ID: Q04KW3_STRP2
UniRef100: UniRef100_P59206
UniRef90: UniRef90_P59206
UniRef50: UniRef50_P59206
UniParc: UPI000012EAA6
EMBL: CP000410
EMBL-CDS: ABJ55408.1
RefSeq_NT: NC_008533.1
EnsemblGenome: EBSTRG00000020457.
EnsemblGenome_TRS: EBSTRT00000020457
EnsemblGenome_PRO: EBSTRP00000019697
GenomeReviews: CP000410_GR
KEGG: spd:SPD_0853
eggNOG: COG5263
HOGENOM: HBG702253
OMA: YYFKSGG
ProtClustDB: CLSK559969
Taxonomy ID 373153
Gene Starting Position 866557
Gene Ending Position 868665
Gene Strand (Orientation) +
Protein Name endo-beta-N-acetylglucosaminidase precursor, putative
DNA Sequence 
>gi|116515308:866557-868665 Streptococcus pneumoniae D39, complete genome
GATGAAGAAAGTAAGATTTATTTTTTTAGCTCTGCTATTTTTCTTAGCTAGTCCAGAGGGTGCAATGGCT
AGTGATGGTACTTGGCAAGGAAAACAGTATCTGAAAGAAGATGGCAGTCAAGCAGCGAATGAGTGGGTTT
TTGATACTCATTATCAATCTTGGTTCTATATAAAAGCAGATGCTAACTATGCTGAAAATGAATGGCTAAA
GCAAGGTGACGACTATTTTTACCTCAAATCTGGTGGCTATATGGCCAAATCAGAATGGGTAGAAGACAAG
GGAGCCTTTTATTATCTTGACCAAGATGGAAAGATGAAAAGAAATGCTTGGGTAGGAACTTCCTATGTTG
GTGCAACAGGTGCCAAAGTAATAGAAGACTGGGTCTATGATTCTCAATACGATGCTTGGTTTTATATCAA
AGCAGATGGACAGCACGCAGAGAAAGAATGGCTCCAAATTAAAGGGAAGGACTATTATTTCAAATCCGGT
GGTTATCTACTGACAAGTCAGTGGATTAATCAAGCTTATGTGAATGCTAGTGGTGCCAAAGTACAGCAAG
GTTGGCTTTTTGACAAACAATACCAATCTTGGTTTTACATCAAAGAAAATGGAAACTATGCTGATAAAGA
ATGGATTTTTGAGAATGGTCACTATTATTATCTAAAATCCGGTGGCTACATGGCAGCCAATGAATGGATT
TGGGATAAGGAATCTTGGTTTTATCTCAAATTTGATGGGAAAATAGCTGAAAAAGAATGGGTCTACGATT
CTCATAGTCAAGCTTGGTACTACTTCAAATCCGGTGGCTACATGGCAGCCAATGAATGGATTTGGGATAA
GGAATCTTGGTTTTACCTCAAGTTTGATGGCAAAATGGCTGAAAAAGAATGGGTCTACGATTCTCATAGT
CAAGCCTGGTACTACTTCAAATCCGGTGGTTACATGACAGCCAATGAATGGATTTGGGATAAGGAATCTT
GGTTTTATCTCAAATCTGATGGGAAAATAGCTGAAAAAGAATGGGTCTACGATTCTCATAGTCAAGCTTG
GTACTACTTCAAATCCGGTGGTTACATGACAGCCAATGAATGGATTTGGGATAAGGAATCTTGGTTTTAC
CTCAAGTCTGATGGCAAAATGGCTGAAAAAGAATGGGTCTACGATTCTCATAGTCAAGCCTGGTACTACT
TCAAATCTGGTGGCTACATGGCGAAAAATGAGACAGTAGATGGTTATCAGCTTGGAAGCGATGGTAAATG
GCTTGGAGGAAAAGCTACAAATAAAAATGCTGCTTACTATCAAGTAGTGCCTGTCACAGCCAATGTTTAT
GATTCAGATGGTGAAAAGCTTTCCTATATATCGCAAGGTAGTGTCGTATGGCTAGATAAGGATAGAAAAA
GTGATGACAAGCGCTTGGCTATTACTATTTCTGGTTTGTCAGGCTATATGAAAACAGAAGATTTACAAGC
GCTAGATGCTAGTAAGGACTTTATCCCTTATTATGAGAGTGATGGCCACCGTTTTTATCACTATGTGGCT
CAGAATGCTAGTATCCCAGTAGCTTCTCATCTTTCTGATATGGAAGTAGGCAAGAAATATTATTCGGCAG
ATGGCCTGCATTTTGATGGTTTTAAGCTTGAGAATCCCTTCCTTTTCAAAGATTTAACAGAGGCTACAAA
CTACAGTGCTGAAGAATTGGATAAGGTATTTAGTTTGCTAAACATTAATAATAGCCTTTTGGAGAACAAG
GGCGCTACTTTTAAGGAAGCCGAAGAACATTACCATATCAATGCCCTTTATCTCCTTGCCCATAGTGCCC
TAGAAAGTAACTGGGGAAGAAGTAAAATTGCCAAAGATAAGAATAATTTCTTTGGCATTACAGCCTATGA
TACGACCCCTTACCTTTCTGCCAAGACATTTGATGATGTGGATAAGGGAATTTTAGGTGCAACCAAGTGG
ATTAAGGAAAATTATATCGATAGGGGAAGAACTTTCCTTGGAAACAAGGCTTCTGGTATGAATGTGGAAT
ATGCTTCAGACCCTTATTGGGGCGAAAAAATTGCTAGTGTGATGATGAAAATCAATGAGAAGCTAGGTGG
CAAAGATTA
Protein Sequence 
>gi|116517112|ref|YP_816335.1| endo-beta-N-acetylglucosaminidase [Streptococcus pneumoniae D39] MKKVRFIFLALLFFLASPEGAMASDGTWQGKQYLKEDGSQAANEWVFDTHYQSWFYIKADANYAENEWLKQGDDYFYLKSGGYMAKSEWVEDKGAFYYLDQDGKMKRNAWVGTSYVGATGAKVIEDWVYDSQYDAWFYIKADGQHAEKEWLQIKGKDYYFKSGGYLLTSQWINQAYVNASGAKVQQGWLFDKQYQSWFYIKENGNYADKEWIFENGHYYYLKSGGYMAANEWIWDKESWFYLKFDGKIAEKEWVYDSHSQAWYYFKSGGYMAANEWIWDKESWFYLKFDGKMAEKEWVYDSHSQAWYYFKSGGYMTANEWIWDKESWFYLKSDGKIAEKEWVYDSHSQAWYYFKSGGYMTANEWIWDKESWFYLKSDGKMAEKEWVYDSHSQAWYYFKSGGYMAKNETVDGYQLGSDGKWLGGKATNKNAAYYQVVPVTANVYDSDGEKLSYISQGSVVWLDKDRKSDDKRLAITISGLSGYMKTEDLQALDASKDFIPYYESDGHRFYHYVAQNASIPVASHLSDMEVGKKYYSADGLHFDGFKLENPFLFKDLTEATNYSAEELDKVFSLLNINNSLLENKGATFKEAEEHYHINALYLLAHSALESNWGRSKIAKDKNNFFGITAYDTTPYLSAKTFDDVDKGILGATKWIKENYIDRGRTFLGNKASGMNVEYASDPYWGEKIASVMMKINEKLGGKD
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: lytB has reduced colonization of nasopharynx of rats compared to wild type (Gosink et al., 2000).
COG COG5263R, under R: General function prediction only
References
Gosink et al., 2000: Gosink KK, Mann ER, Guglielmo C, Tuomanen EI, Masure HR. Role of novel choline binding proteins in virulence of Streptococcus pneumoniae. Infection and immunity. 2000; 68(10); 5690-5695. [PubMed: 10992472].