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pgdA from Streptococcus pneumoniae D39

Victor ID 3072
Gene Name pgdA from Streptococcus pneumoniae D39
Sequence Strain (Species/Organism) Streptococcus pneumoniae D39
NCBI Gene ID 4441553
NCBI Protein GI 116515788
Locus Tag SPD_1309
Protein Accession YP_816775.1
Other Database IDs UniProtKB-ID: Q04JM3_STRP2
UniRef100: UniRef100_Q04JM3
UniRef90: UniRef90_Q04JM3
UniRef50: UniRef50_Q04JM3
UniParc: UPI0000E53308
EMBL: CP000410
EMBL-CDS: ABJ54084.1
RefSeq_NT: NC_008533.1
EnsemblGenome: EBSTRG00000020193.
EnsemblGenome_TRS: EBSTRT00000020193
EnsemblGenome_PRO: EBSTRP00000019433
GenomeReviews: CP000410_GR
KEGG: spd:SPD_1309
eggNOG: COG0726
HOGENOM: HBG703418
OMA: AHELYYS
ProtClustDB: CLSK884105
Taxonomy ID 373153
Gene Starting Position 1327260
Gene Ending Position 1328702
Gene Strand (Orientation) -
Protein Name peptidoglycan GlcNAc deacetylase
DNA Sequence 
>gi|116515308:1327260-1328702 Streptococcus pneumoniae D39, complete genome
CTTATTCATCACGACTATAGTACAGCTCATGAGCTTTTAGGCGAGTATTGAGCATCTCTGGTATGGTCAC
AAAGGTATAACCTTGATTTTTCAAATACTCAATGACCCTTGGCAAGGCATTGACTGTCGGACTGTGAATA
TCATGCATCAAAACGATAGAGCCATTAGCTACTTGATGCTGAATTTCTGTCAAAATAGATGCTTCATTTT
TACTCTTCCAGTCCAGACTATCCACATCCCACATGATAAAGCTCAAATCCAAGCTATTGCGAATATCATC
TGTAATAGCACCATAAGGTGGACGCATGAGTTTAGAACTAGAACCCAGCACTTTAGTTAGCACATCCTCA
GTATCAGTAATCTGCTTTTTAGCTTCATCAAGAGAGAGTTGCGAGAGAATCGGATGGCTCCAGCTATGGT
TTCCAACAACATGACCTTCAGATTTTATCCTCTTCACCAAGTCCTCATTCCCAGAAACATTTTTCCCAAG
CACAAAGAAAGTCGCTTTAATATCATATTTAGCTAGGGTCTCTAATACCTGCGGGGTCGTTGCTGGATTT
GGACCATCATCAAAGGTTAGAGCGACAACTTTTTGATGTTTCTTATCAAAGTAAGATTGGTACAAGGCCG
CATCTTTTTCGAGTAAGTACGAAGATTGGATAACATCAAAGAAAGCAGATACTGGCAAGGCTATCTCTTC
TAAATTTTCAACCACAGGACTTGGATAAAGGATAATCTGACTATCCTTGTAATCAAAATTCCATGCAGAC
AAGTCTTGGTCAGAGAAGTTTTTTACAATCTGCTCACTCTGGTCTTGCTCTATTTTTTTATCCTCTATGA
AGGAGGTCAACTCTTTTATCAGCTGTTCCTTAGCCTTACTAGCATCTGAAAACAGTTGGTCAAGTGTAAA
AGGTTGCCCATCTTCTGTTAAGTGAACCTTTCCTAGACTGGTCTTTTCAGTCTCTTCAATCTTAAAAGCA
ACTAAATCATAGATTTGTTTGGTCACATTACGATTAACGACTCCCTTTAAACCTGACTCTTCTTGCTCTG
TATAGTAGAAAACAAGATTGTCCTTACTTTCTAGCTTGTCCTTAACATCTTGATTTATCAGCTCCCTAAC
AGAGGAAATCACTTTCTCCCCTTGGAGAGGATAATAGGCAATCACTTCGGCTTGCCCCTGACGAAAATGC
TCCTTCTGATTTCCCTCACTCAATTGATCATCTTTCTCTTTTTTGAGCGATTCAATCTTTTGCTCAAAAC
TTTTTTGCTGGTAGATCTTAAAAGCAATAAATCCGCCTAATAGGCAAATAGAAATTGCTAAAATACCAAT
CAAAGCCAATAATACATGTCTCGTTTTCCCGTGTCTGCCACGTCCTAGTCTACTTTTATTCATATTTATA
TCATAACAAATTTGAGCAATAATTTCAATGATACAATTTGGCA
Protein Sequence 
>gi|116515788|ref|YP_816775.1| peptidoglycan GlcNAc deacetylase [Streptococcus pneumoniae D39] MPNCIIEIIAQICYDINMNKSRLGRGRHGKTRHVLLALIGILAISICLLGGFIAFKIYQQKSFEQKIESLKKEKDDQLSEGNQKEHFRQGQAEVIAYYPLQGEKVISSVRELINQDVKDKLESKDNLVFYYTEQEESGLKGVVNRNVTKQIYDLVAFKIEETEKTSLGKVHLTEDGQPFTLDQLFSDASKAKEQLIKELTSFIEDKKIEQDQSEQIVKNFSDQDLSAWNFDYKDSQIILYPSPVVENLEEIALPVSAFFDVIQSSYLLEKDAALYQSYFDKKHQKVVALTFDDGPNPATTPQVLETLAKYDIKATFFVLGKNVSGNEDLVKRIKSEGHVVGNHSWSHPILSQLSLDEAKKQITDTEDVLTKVLGSSSKLMRPPYGAITDDIRNSLDLSFIMWDVDSLDWKSKNEASILTEIQHQVANGSIVLMHDIHSPTVNALPRVIEYLKNQGYTFVTIPEMLNTRLKAHELYYSRDE
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: pgdA mutant is attenuated in mice (Vollmer and Tomasz, 2002).
COG COG0726G, under G: Carbohydrate transport and metabolism
References
Vollmer and Tomasz, 2002: Vollmer W, Tomasz A. Peptidoglycan N-acetylglucosamine deacetylase, a putative virulence factor in Streptococcus pneumoniae. Infection and immunity. 2002; 70(12); 7176-7178. [PubMed: 12438406].