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lytC from Streptococcus pneumoniae D39

Victor ID 3071
Gene Name lytC from Streptococcus pneumoniae D39
Sequence Strain (Species/Organism) Streptococcus pneumoniae D39
NCBI Gene ID 4441545
NCBI Protein GI 116515853
Locus Tag SPD_1403
Protein Accession YP_816863.1
Other Database IDs UniProtKB-ID: Q04JH5_STRP2
UniRef100: UniRef100_Q04JH5
UniRef90: UniRef90_B2IR92
UniRef50: UniRef50_D3HAA5
UniParc: UPI0000E53317
EMBL: CP000410
EMBL-CDS: ABJ54149.1
RefSeq_NT: NC_008533.1
EnsemblGenome: EBSTRG00000020679.
EnsemblGenome_TRS: EBSTRT00000020679
EnsemblGenome_PRO: EBSTRP00000019919
GenomeReviews: CP000410_GR
KEGG: spd:SPD_1403
eggNOG: COG5263
HOGENOM: HBG697709
OMA: KKWGYMA
ProtClustDB: CLSK560466
Taxonomy ID 373153
Gene Starting Position 1422041
Gene Ending Position 1423513
Gene Strand (Orientation) -
Protein Name 1,4-beta-N-acetylmuramidase, putative
DNA Sequence 
>gi|116515308:1422041-1423513 Streptococcus pneumoniae D39, complete genome
CTTAATACCAAACGCTGACATCTACGCGCCCTTGGATTCCTTTCATGTATTCAGAAGAGGTATATTGCCA
ACCTTTTTCTCCTGAATAATAAGGGTTTTCCCATTCTAAAGCATTCGTATAGGCCGCTACCCAGTTTACA
TGTTTTAAAATATCTGGGTGTTTTAAACGCGTCTGTAATAAACTACGATAGCTATAGACATATACATTTT
GATAACCCGCCTGCTTCATCGTGTCCATGTACTTGTTGATGATTTTAACCCAAGTGTCTGTATCACTTGG
AGCTCTCTTGCTCTTATTTACATATTCCCAGTTCTCAACATCATAATAGATAGGGTAAGACAGGTTCATA
TTGTATTTCTTTATAAGTTCAATGGTCTGTTTAGCGTCATTCTCAGCATCGGTCTCATTTTCAGCATAGG
TATAGAGATAGACACCATAAGGAATTCCCAGACGGTTTAACTCCTTAATGTTATGCGCCAATTCCTTGTC
TTCTTTACCGCTATAACCTAGACGAACAATGACACCATCCACCTCGTTCTCATCAATAACCTTTTTCCAA
TCATTGATACGACCATTGTGCTCACTAATATCAATGATTTTCTTAGCATGTTCGGTTCCCACTTGTTCTT
CTCTATTATTAAAGAAATAGCGTTTACCATCTCTGTGAACCCAGCCGACATTCAAATCTTTCTTTTCTTT
GAGCTCACCAGAGGCCGCAAAGATATAGCGAGCACCATCCATAATCACTTCGTCAGTCGCCATGGCACCA
CTTCCAGTCAAATAGTAGTTGCCTTGCCACTCATTCCGAGCCATATAGCCCCACTTCTTGAAATAGTACC
ATTTGCCGCCCACTTTTTGCCACTCTTGGTTAGCATAAGTTCCATCGGATTTTAGATAAAAATAAGCAGA
ATAAGCTGGATCATAGAGCCATTCATTTTGTATCATAGCTCCTTGACCATTCAAGAAATAACTTCCTTGC
CATTGGCTTTTAGCCATGTAACCCCACTTCTTGAAGTAGTACCACTTATTTCCAATCAATTGCCATTCTT
GATGAGCATAAGCCCCATCTGACTTGAGATAAAACCAACTCTTGTAATTACTGTCATAGATCCACTCGTT
TTGGGCCATATATCCACCTGATTTCAGGTAGTAATTTCCATGCCATTCATTCTGCGAGTAACGACCATCT
GAATTAATATAAAACCAAGCCTTATAGTAGTTGTCAAAAATCCATTCACTTTGAGCTTTAGAACCATCAT
CCTTTACATAATAATCCCCATCCCAGTAGGCAGCAGCATTAGTCTGTACTTCTGCGCTCGTTTGCGTTTT
ATTAGAAGACTGATTTTGCTCTGAACTACTTGAAGCTGTCGTTGTATCCTGCGAAGTTTTTGCTACTTCA
GTTTCATTTGCAGCGACATGACTAGTTGCCAAGCCTAGTAAACAGATACTTGCTAATCCAATTTTTATTT
TCA
Protein Sequence 
>gi|116515853|ref|YP_816863.1| 1,4-beta-N-acetylmuramidase [Streptococcus pneumoniae D39] MKIKIGLASICLLGLATSHVAANETEVAKTSQDTTTASSSSEQNQSSNKTQTSAEVQTNAAAYWDGDYYVKDDGSKAQSEWIFDNYYKAWFYINSDGRYSQNEWHGNYYLKSGGYMAQNEWIYDSNYKSWFYLKSDGAYAHQEWQLIGNKWYYFKKWGYMAKSQWQGSYFLNGQGAMIQNEWLYDPAYSAYFYLKSDGTYANQEWQKVGGKWYYFKKWGYMARNEWQGNYYLTGSGAMATDEVIMDGARYIFAASGELKEKKDLNVGWVHRDGKRYFFNNREEQVGTEHAKKIIDISEHNGRINDWKKVIDENEVDGVIVRLGYSGKEDKELAHNIKELNRLGIPYGVYLYTYAENETDAENDAKQTIELIKKYNMNLSYPIYYDVENWEYVNKSKRAPSDTDTWVKIINKYMDTMKQAGYQNVYVYSYRSLLQTRLKHPDILKHVNWVAAYTNALEWENPYYSGEKGWQYTSSEYMKGIQGRVDVSVWY
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: lytC mutant have reduced colonization of rat nasopharynx compared to wild type (Gosink et al., 2000).
COG COG5263R, under R: General function prediction only
References
Gosink et al., 2000: Gosink KK, Mann ER, Guglielmo C, Tuomanen EI, Masure HR. Role of novel choline binding proteins in virulence of Streptococcus pneumoniae. Infection and immunity. 2000; 68(10); 5690-5695. [PubMed: 10992472].