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cbpE from Streptococcus pneumoniae D39

Victor ID 3070
Gene Name cbpE from Streptococcus pneumoniae D39
Sequence Strain (Species/Organism) Streptococcus pneumoniae D39
NCBI Gene ID 4441485
NCBI Protein GI 116516225
Locus Tag SPD_0821
Protein Accession YP_816304.1
Other Database IDs UniProtKB-ID: Q04KZ4_STRP2
UniRef100: UniRef100_Q04KZ4
UniRef90: UniRef90_B8ZP33
UniRef50: UniRef50_D3H8I6
UniParc: UPI00000B90E6
EMBL: CP000410
EMBL-CDS: ABJ54521.1
RefSeq_NT: NC_008533.1
EnsemblGenome: EBSTRG00000020228.
EnsemblGenome_TRS: EBSTRT00000020228
EnsemblGenome_PRO: EBSTRP00000019468
GenomeReviews: CP000410_GR
KEGG: spd:SPD_0821
eggNOG: COG5263
HOGENOM: HBG702245
OMA: HYYLEES
ProtClustDB: CLSK559958
Taxonomy ID 373153
Gene Starting Position 838510
Gene Ending Position 840393
Gene Strand (Orientation) +
Protein Name choline binding protein E
DNA Sequence 
>gi|116515308:838510-840393 Streptococcus pneumoniae D39, complete genome
AATGAAAAAGAAATTAACTAGTTTAGCACTTGTAGGCGCTTTTTTAGGTTTGTCATGGTATGGGAATGTT
CAGGCTCAAGAAAGTTCAGGAAATAAAATCCACTTTATCAATGTTCAAGAAGGTGGCAGTGATGCGATTA
TTCTTGAAAGCAATGGACATTTTGCCATGGTGGATACAGGAGAAGATTATGATTTCCCAGATGGAAGTGA
TTCTCGTTATCCATGGAGAGAAGGAATTGAAACGTCTTATAAGCATGTTCTAACAGACCGTGTCTTTCGT
CGTTTGAAGGAATTGAGTGTCCAAAAACTTGATTTTATTTTGGTGACCCATACCCACAGTGATCATATTG
GAAATGTTGATGAATTACTGTCTACCTATCCAGTTGACCGAGTCTATCTTAAGAAATATAGTGATAGTCG
TATTACTAATTCTGAACGTCTATGGGATAATCTGTATGGCTATGATAAGGTTTTACAGACTGCTACAGAA
ACAGGTGTTTCAGTTATTCAAAATATCACACAAGGGGATGCTCATTTTCAGTTTGGGGACATGGATATTC
AGCTCTATAATTATGAAAATGAAACTGATTCATCGGGTGAATTAAAGAAAATTTGGGATGACAATTCCAA
TTCCTTGATTAGCGTGGTGAAAGTCAATGGCAAGAAAATTTACCTTGGGGGCGATTTAGATAATGTTCAT
GGAGCAGAAGACAAGTATGGTCCTCTCATTGGAAAAGTTGATTTGATGAAGTTTAATCATCACCATGATA
CCAACAAATCAAATACCAAGGATTTCATTAAAAATTTGAGTCCGAGTTTGATTGTTCAAACTTCGGATAG
TCTACCTTGGAAAAATGGTGTTGATAGTGAGTATGTTAATTGGCTCAAAGAACGAGGAATTGAGAGAATC
AACGCAGCCAGCAAAGACTATGATGCAACAGTTTTTGATATTCGAAAAGACGGTTTTGTCAATATTTCAA
CATCCTACAAGCCGATTCCAAGTTTTCAAGCTGGTTGGCATAAGAGTGCATATGGGAACTGGTGGTATCA
AGCGCCTGATTCTACAGGAGAGTATGCTGTCGGTTGGAATGAAATCGAAGGTGAATGGTATTACTTTAAC
CAAACGGGTATCTTGTTACAGAATCAATGGAAAAAATGGAACAATCATTGGTTCTATTTGACAGACTCTG
GTGCTTCTGCTAAAAATTGGAAGAAAATTGATGGAATCTGGTATTATTTTAACAAAGAAAATCAGATGGA
AATTGGTTGGGTTCAAGATAAAGAGCAGTGGTATTATTTGGATGTTGATGGTTCTATGAAGACAGGATGG
CTTCAATATATGGGGCAATGGTATTACTTTGCTCCATCAGGGGAAATGAAAATGGGCTGGGTAAAAGATA
AAGAAACCTGGTACTATATGGATTCTACTGGTGTCATGAAGACAGGTGAGATAGAAGTTGCTGGTCAACA
TTATTATCTGGAAGATTCAGGAGCTATGAAGCAAGGCTGGCATAAAAAGGCAAATGATTGGTATTTCTAC
AAGACAGACGGTTCACGAGCTGTGGGTTGGATCAAGGACAAGGATAAATGGTACTTCTTGAAAGAAAATG
GTCAATTACTTGTGAACGGTAAGACACCAGAAGGTTATACTGTGGATTCAAGTGGTGCCTGGTTAGTGGA
TGTTTCGATCGAGAAATCTGCTACAATTAAAACTACAAGTCATTCAGAAATAAAAGAATCCAAAGAAGTA
GTGAAAAAGGATCTTGAAAATAAAGAAACGAGTCAACATGAAAGTGTTACAAATTTTTCAACTAGTCAAG
ATTTGACATCCTCAACTTCACAAAGCTCTGAAACGAGTGTAAACAAATCGGAATCAGAACAGTA
Protein Sequence 
>gi|116516225|ref|YP_816304.1| choline binding protein E [Streptococcus pneumoniae D39] MKKKLTSLALVGAFLGLSWYGNVQAQESSGNKIHFINVQEGGSDAIILESNGHFAMVDTGEDYDFPDGSDSRYPWREGIETSYKHVLTDRVFRRLKELSVQKLDFILVTHTHSDHIGNVDELLSTYPVDRVYLKKYSDSRITNSERLWDNLYGYDKVLQTATETGVSVIQNITQGDAHFQFGDMDIQLYNYENETDSSGELKKIWDDNSNSLISVVKVNGKKIYLGGDLDNVHGAEDKYGPLIGKVDLMKFNHHHDTNKSNTKDFIKNLSPSLIVQTSDSLPWKNGVDSEYVNWLKERGIERINAASKDYDATVFDIRKDGFVNISTSYKPIPSFQAGWHKSAYGNWWYQAPDSTGEYAVGWNEIEGEWYYFNQTGILLQNQWKKWNNHWFYLTDSGASAKNWKKIDGIWYYFNKENQMEIGWVQDKEQWYYLDVDGSMKTGWLQYMGQWYYFAPSGEMKMGWVKDKETWYYMDSTGVMKTGEIEVAGQHYYLEDSGAMKQGWHKKANDWYFYKTDGSRAVGWIKDKDKWYFLKENGQLLVNGKTPEGYTVDSSGAWLVDVSIEKSATIKTTSHSEIKESKEVVKKDLENKETSQHESVTNFSTSQDLTSSTSQSSETSVNKSESEQ
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: cbpE has reduced colonization of nasopharynx of rats and reduced adherence to human epithelial cells (Gosink et al., 2000).
COG COG5263R, under R: General function prediction only
References
Gosink et al., 2000: Gosink KK, Mann ER, Guglielmo C, Tuomanen EI, Masure HR. Role of novel choline binding proteins in virulence of Streptococcus pneumoniae. Infection and immunity. 2000; 68(10); 5690-5695. [PubMed: 10992472].