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mce4C

Victor ID 307
Gene Name mce4C
Sequence Strain (Species/Organism) Mycobacterium tuberculosis H37Rv
NCBI Gene ID 888354
NCBI Protein GI 15610633
Locus Tag Rv3497c
Protein Accession NP_218014.1
Other Database IDs UniProtKB-ID: O53542_MYCTU
UniRef100: UniRef100_A5U8H2
UniRef90: UniRef90_A5U8H2
UniRef50: UniRef50_A5U8H2
UniParc: UPI00000D5EBB
EMBL: AE000516
EMBL: BX842583
EMBL-CDS: AAK47960.1
EMBL-CDS: CAA17734.1
RefSeq_NT: NC_000962.2
RefSeq_NT: NC_002755.2
EnsemblGenome: EBMYCG00000002754.
EnsemblGenome_TRS: EBMYCT00000002756
EnsemblGenome_PRO: EBMYCP00000002756
EnsemblGenome: EBMYCG00000070971.
EnsemblGenome_TRS: EBMYCT00000070976
EnsemblGenome_PRO: EBMYCP00000069035
GenomeReviews: AE000516_GR
GenomeRev
Taxonomy ID 83332
Gene Starting Position 3915882
Gene Ending Position 3916955
Gene Strand (Orientation) -
Protein Name MCE-FAMILY PROTEIN MCE4C
DNA Sequence 
>gi|57116681:3915882-3916955 Mycobacterium tuberculosis H37Rv, complete genome
ATCACGGCGACTTCGGTCTGATGATCCAGCGCTCCTGGATAAACCCGCGCAAGTAATCGGCGAGGCTATC
CGGCAGCTTGCCCGGCTGAAAGACCAGGTCGAACACGGTCGCCACCAGCGGCCCGGGCAGCACGCTGTAG
ACGTTGACATTGAATCCGGGTCCGGATCCGACCACCTCCCCCAGCGTGGTCGCGTACGTGGGCAGCCGCT
TGAGGGCCTCGGTGATATAGTCGCGGCGCTCGTTGAGGTTGGCCAGCACCAGGTTGAGCTTGCTCAAAGC
CGGGCCGAACTCCTTACGGTTGTCGGCGACAAAGCCGGAAATCTGCGCTGCAACATCGTCGATCCCAGAG
ATCAACGCGCTGAGCGCGGCCCGCCGGGCATCGAGCGCCGCAAACAACTGGTTGCCGTCCTCGACCAGCT
TGTTGACCTGTTCGGCGCGTTCGGACAACACCGATGTCACCGACTTGGCGTGCGCCAGCAGGCCTTGCAG
CGCTTCGTCGCGACGATTCAGGGCGCGCGACAGCGACGTCAGCCCGTCCACGGCACCACGCACCTGCGGG
GTGGCGTCATGCAAGGCCTGGGTGAACACGTTCAAGGCCTGCTCGAACTGCGGCCTATTCAGGTCGTTGG
CGTTGCGGCCCAGATCCTGCAGCACCCCGTTGAGCGTGTAGGGCGTGGTGGTCCGGCTCAACGGAATCGT
GGTCGACTTGCCGGAGCCAGCCGGACTGACCGCGATGGAGCGCTCGCCGAGGATGGTGTCGGTGCGGATC
GCGGCCAGGGACTGGTCGCCGACGACGATGCTGCGGTCCACGCTGAAGGTGACCTTTGCACTGTTTCCGG
CCAGACTCACGGCCGACACCGCGCCCACCTTGAGGCCCGAGACATAAACCGAGTTACCGGGGGTGATCCC
ACCGGCGTCGGTGAAATACGCGTCGTAGGTTTTGCCCTGTGGCCAGAAAGGCAACCCGCTGTAGCCGAAT
GCGATCAGGACGACGCAGATCACCAGCACCAGGCCGAAGATGCCGGTGCGGAGCGGGTCGCGTTCGTGTT
TGCTACTTGGCTTCCTATTTAGCA
Protein Sequence 
>gi|15610633|ref|NP_218014.1| Mce family protein Mce4C [Mycobacterium tuberculosis H37Rv] MLNRKPSSKHERDPLRTGIFGLVLVICVVLIAFGYSGLPFWPQGKTYDAYFTDAGGITPGNSVYVSGLKVGAVSAVSLAGNSAKVTFSVDRSIVVGDQSLAAIRTDTILGERSIAVSPAGSGKSTTIPLSRTTTPYTLNGVLQDLGRNANDLNRPQFEQALNVFTQALHDATPQVRGAVDGLTSLSRALNRRDEALQGLLAHAKSVTSVLSERAEQVNKLVEDGNQLFAALDARRAALSALISGIDDVAAQISGFVADNRKEFGPALSKLNLVLANLNERRDYITEALKRLPTYATTLGEVVGSGPGFNVNVYSVLPGPLVATVFDLVFQPGKLPDSLADYLRGFIQERWIIRPKSP
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: attenuated in mice (Sassetti and Rubin, 2003).
COG COG1463Q, under Q: Secondary metabolites biosynthesis, transport and catabolism
References
Sassetti and Rubin, 2003: Sassetti CM, Rubin EJ. Genetic requirements for mycobacterial survival during infection. Proceedings of the National Academy of Sciences of the United States of America. 2003; 100(22); 12989-12994. [PubMed: 14569030].