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luxS from Streptococcus pneumoniae D39

Victor ID 3068
Gene Name luxS from Streptococcus pneumoniae D39
Sequence Strain (Species/Organism) Streptococcus pneumoniae D39
NCBI Gene ID 4441459
NCBI Protein GI 116516199
Locus Tag SPD_0309
Protein Accession YP_815826.1
Other Database IDs UniProtKB-ID: LUXS_STRP2
UniRef100: UniRef100_Q04MC2
UniRef90: UniRef90_Q04MC2
UniRef50: UniRef50_Q1JAI5
UniParc: UPI00000513CE
EMBL: CP000410
EMBL-CDS: ABJ54495.1
RefSeq_NT: NC_008533.1
EnsemblGenome: EBSTRG00000019822
EnsemblGenome_TRS: EBSTRT00000019822
EnsemblGenome_PRO: EBSTRP00000019062
GenomeReviews: CP000410_GR
KEGG: spd:SPD_0309
eggNOG: COG1854
HOGENOM: HBG347473
OMA: VRIAKTM
ProtClustDB: PRK02260
Taxonomy ID 373153
Gene Starting Position 308501
Gene Ending Position 308983
Gene Strand (Orientation) -
Protein Name S-ribosylhomocysteinase
DNA Sequence 
>gi|116515308:308501-308983 Streptococcus pneumoniae D39, complete genome
TTTAAATCACATGACGTTCAAAGGCATCATCTGAAATCCCTTGTTCCAAGATGAGTTTTGCCCATTCTTT
AGCAGAGAAGAGGCTGTGGTCCTTGTAGTTTCCGCAAGATTCGATGGTTGTCCCTGGGACATCTTCCCAA
GTAGTAGTTTCAGCGATTTCCTTGAGCGAATCCTTGATAACAGCTGCGATTTTAGCACTGGTGTGACGTC
CCCACATAATCATGTGGAAGCCTGTGCGGCAACCAAATGGTGAACAGTCAATCATGCCGTCAATGCGGGT
ACGGATGAGTTTGGCTAAGAGGTGCTCGATAGTGTGAAGGCCGGCAGTAGGGATAGAGTCTTCGTTTGGC
TGCACCAAGCGAATATCATAATTGGAGATGATGTCTCCTTTTGGTCCTGTTTCTTCCCCAATCAAGCGAA
CATAGGGTGCTTTGACAATGGTGTGGTCAAGTTCAAAACTTTCGACAATAACTTCTTTTGACA
Protein Sequence 
>gi|116516199|ref|YP_815826.1| S-ribosylhomocysteinase [Streptococcus pneumoniae D39] MSKEVIVESFELDHTIVKAPYVRLIGEETGPKGDIISNYDIRLVQPNEDSIPTAGLHTIEHLLAKLIRTRIDGMIDCSPFGCRTGFHMIMWGRHTSAKIAAVIKDSLKEIAETTTWEDVPGTTIESCGNYKDHSLFSAKEWAKLILEQGISDDAFERHVI
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: luxS mutant has defective ability to persist in the nasopharyngeal tissues of mice (Joyce et al., 2004).
COG COG1854T, under T: Signal transduction mechanisms
References
Joyce et al., 2004: Joyce EA, Kawale A, Censini S, Kim CC, Covacci A, Falkow S. LuxS is required for persistent pneumococcal carriage and expression of virulence and biosynthesis genes. Infection and immunity. 2004; 72(5); 2964-2975. [PubMed: 15102809].