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regR from Streptococcus pneumoniae D39

Victor ID 3067
Gene Name regR from Streptococcus pneumoniae D39
Sequence Strain (Species/Organism) Streptococcus pneumoniae D39
NCBI Gene ID 4441432
NCBI Protein GI 116515692
Locus Tag SPD_0301
Protein Accession YP_815818.1
Other Database IDs UniProtKB-ID: Q04MD0_STRP2
UniRef100: UniRef100_Q04MD0
UniRef90: UniRef90_B2ISP9
UniRef50: UniRef50_D6ZQH0
UniParc: UPI00000AFE72
EMBL: CP000410
EMBL-CDS: ABJ53988.1
RefSeq_NT: NC_008533.1
EnsemblGenome: EBSTRG00000018860.
EnsemblGenome_TRS: EBSTRT00000018860
EnsemblGenome_PRO: EBSTRP00000018100
GenomeReviews: CP000410_GR
KEGG: spd:SPD_0301
eggNOG: COG1609
HOGENOM: HBG753640
OMA: ISISRRC
ProtClustDB: CLSK797399
Taxonomy ID 373153
Gene Starting Position 298961
Gene Ending Position 299962
Gene Strand (Orientation) +
Protein Name sugar binding transcriptional regulator RegR
DNA Sequence 
>gi|116515308:298961-299962 Streptococcus pneumoniae D39, complete genome
ATTGGAGAAGAAACTGACCATAAAAGACATTGCGGAAATGGCTCAGACCTCGAAAACAACCGTGTCATTT
TACCTAAACGGGAAATATGAAAAAATGTCCCAAGAGACACGTGAAAAGATTGAAAAAGTTATTCATGAAA
CAAATTACAAACCGAGCATTGTTGCGCGTAGCTTAAACTCCAAACGAACAAAATTAATCGGTGTTTTGAT
CGGTGATATTACCAACAGTTTCTCAAACCAAATTGTTAAGGGAATTGAGGATATCGCCAGCCAGAATGGC
TACCAGGTAATGATAGGAAATAGTAATTACAGCCAAGAGAGTGAGGACCGGTATATTGAAAGCATGCTTC
TCTTGGGAGTAGACGGCTTTATTATTCAGCCGACCTCTAATTTCCGAAAATATTCTCGTATCATCGATGA
GAAAAAGAAGAAAATGGTCTTTTTTGATAGTCAGCTCTATGAACACCGGACTAGCTGGGTTAAAACCAAT
AACTATGATGCCGTTTATGACATGACCCAGTCCTGTATCGAAAAAGGTTATGAGTATTTTCTCTTGATTA
CAGCGGATACGAGTCGTTTGAGTACTCGGATTGAGCGGGCAAGTGGTTTTGTGGATGCTTTAACAGATGC
TAATATGCGTCACGCCAGTCTAACCATTGAAGATAAGCATACGAATTTGGAACAAATTAAGGAATTTTTA
CAAAAAGAAATCGATCCCGATGAAAAAACTCTGGTATTTATCCCTAACTGTTGGGCCCTACCTCTAGTCT
TTACCGTTATCAAAGAGTTGAATTATAACTTGCCGCAAGTTGGGTTGATTGGTTTTGACAATACGGAGTG
GACTTGCTTTTCTTCTCCAAGTGTTTCGACGCTGGTTCAGCCCTCCTTTGAGGAAGGACAACAGGCTACA
AAGATTTTGATTGACCAGATTGAAGGCCGCAATCAAGAAGAAAGGCAACAAGTCTTGGATTGTAGTGTGA
ATTGGAAAGAGTCGACTTTCTA
Protein Sequence 
>gi|116515692|ref|YP_815818.1| sugar binding transcriptional regulator RegR [Streptococcus pneumoniae D39] MEKKLTIKDIAEMAQTSKTTVSFYLNGKYEKMSQETREKIEKVIHETNYKPSIVARSLNSKRTKLIGVLIGDITNSFSNQIVKGIEDIASQNGYQVMIGNSNYSQESEDRYIESMLLLGVDGFIIQPTSNFRKYSRIIDEKKKKMVFFDSQLYEHRTSWVKTNNYDAVYDMTQSCIEKGYEYFLLITADTSRLSTRIERASGFVDALTDANMRHASLTIEDKHTNLEQIKEFLQKEIDPDEKTLVFIPNCWALPLVFTVIKELNYNLPQVGLIGFDNTEWTCFSSPSVSTLVQPSFEEGQQATKILIDQIEGRNQEERQQVLDCSVNWKESTF
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: regR mutant is attenuated in mice (Chapuy-Regaud et al., 2003).
COG COG1609K, under K: Transcription
References
Chapuy-Regaud et al., 2003: Chapuy-Regaud S, Ogunniyi AD, Diallo N, Huet Y, Desnottes JF, Paton JC, Escaich S, Trombe MC. RegR, a global LacI/GalR family regulator, modulates virulence and competence in Streptococcus pneumoniae. Infection and immunity. 2003; 71(5); 2615-2625. [PubMed: 12704136].