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luxS from Streptococcus pneumoniae Hungary19A-6

Victor ID 3059
Gene Name luxS from Streptococcus pneumoniae Hungary19A-6
Sequence Strain (Species/Organism) Streptococcus pneumoniae Hungary19A-6
NCBI Gene ID 6029035
NCBI Protein GI 169833604
Locus Tag SPH_0450
Protein Accession YP_001693860.1
Other Database IDs UniProtKB-ID: LUXS_STRPI
UniRef100: UniRef100_Q04MC2
UniRef90: UniRef90_Q04MC2
UniRef50: UniRef50_Q1JAI5
UniParc: UPI00000513CE
EMBL: CP000936
EMBL-CDS: ACA36718.1
RefSeq_NT: NC_010380.1
EnsemblGenome: EBSTRG00000023925
EnsemblGenome_TRS: EBSTRT00000023925
EnsemblGenome_PRO: EBSTRP00000023091
GenomeReviews: CP000936_GR
KEGG: spv:SPH_0450
HOGENOM: HBG347473
OMA: VRIAKTM
ProtClustDB: PRK02260
BioCyc: SPNE487214:SPH_0450-MONOMER
Taxonomy ID 487214
Gene Starting Position 399677
Gene Ending Position 400159
Gene Strand (Orientation) -
Protein Name S-ribosylhomocysteinase LuxS
DNA Sequence 
>gi|169832377:399677-400159 Streptococcus pneumoniae Hungary19A-6, complete genome
TTTAAATCACATGACGTTCAAAGGCATCATCTGAAATCCCTTGTTCCAAGATGAGTTTTGCCCATTCTTT
AGCAGAGAAGAGGCTGTGGTCCTTGTAGTTTCCGCAAGATTCGATGGTTGTCCCTGGGACATCTTCCCAA
GTAGTAGTTTCAGCGATTTCCTTGAGCGAATCCTTGATAACAGCTGCAATTTTAGCACTGGTGTGACGTC
CCCACATAATCATGTGGAAGCCTGTGCGGCAACCAAATGGCGAACAGTCAATCATGCCGTCAATGCGGGT
ACGGATGAGTTTGGCTAAGAGGTGCTCGATAGTGTGAAGGCCGGCGGTAGGGATGGAGTCTTCGTTTGGT
TGCACCAAGCGAATATCATAATTGGAGATGATGTCTCCTTTTGGTCCTGTTTCTTCCCCAATCAAGCGAA
CATAGGGTGCTTTGACAATGGTGTGGTCAAGTTCAAAACTTTCGACAATAACTTCTTTTGACA
Protein Sequence 
>gi|169833604|ref|YP_001693860.1| S-ribosylhomocysteinase [Streptococcus pneumoniae Hungary19A-6] MSKEVIVESFELDHTIVKAPYVRLIGEETGPKGDIISNYDIRLVQPNEDSIPTAGLHTIEHLLAKLIRTRIDGMIDCSPFGCRTGFHMIMWGRHTSAKIAAVIKDSLKEIAETTTWEDVPGTTIESCGNYKDHSLFSAKEWAKLILEQGISDDAFERHVI
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: luxS mutant has defective ability to persist in the nasopharyngeal tissues of mice (Joyce et al., 2004).
COG COG1854T, under T: Signal transduction mechanisms
References
Joyce et al., 2004: Joyce EA, Kawale A, Censini S, Kim CC, Covacci A, Falkow S. LuxS is required for persistent pneumococcal carriage and expression of virulence and biosynthesis genes. Infection and immunity. 2004; 72(5); 2964-2975. [PubMed: 15102809].