Search: for Help
About
Introduction
Statistics
Your PHIDIAS
Register or Login
Philert
Submission
Curated Data
Victors
BBP (Brucella)
Phinfo
Phinet
HazARD
Data Analysis
Phigen
Pacodom
BLAST
Help & Documents
Documents
FAQs
Links
Acknowledgements
Disclaimer
Contact Us
UMMS Logo

ciaR from Streptococcus pneumoniae CGSP14

Victor ID 3050
Gene Name ciaR from Streptococcus pneumoniae CGSP14
Sequence Strain (Species/Organism) Streptococcus pneumoniae CGSP14
NCBI Gene ID 6218247
NCBI Protein GI 182683717
Locus Tag SPCG_0747
Protein Accession YP_001835464.1
Other Database IDs UniProtKB-ID: B2INS2_STRPS
UniRef100: UniRef100_P0A4H8
UniRef90: UniRef90_P0A4H8
UniRef50: UniRef50_P0A4H8
UniParc: UPI00000515B6
EMBL: CP001033
EMBL-CDS: ACB89999.1
RefSeq_NT: NC_010582.1
EnsemblGenome: EBSTRG00000018727.
EnsemblGenome_TRS: EBSTRT00000018727
EnsemblGenome_PRO: EBSTRP00000018041
GenomeReviews: CP001033_GR
KEGG: spw:SPCG_0747
HOGENOM: HBG753323
OMA: VILPKEQ
ProtClustDB: CLSK876907
Taxonomy ID 516950
Gene Starting Position 738909
Gene Ending Position 739649
Gene Strand (Orientation) +
Protein Name DNA-binding response regulator CiaR
DNA Sequence 
>gi|182682970:738909-739649 Streptococcus pneumoniae CGSP14, complete genome
AATGCAGAGAGTTGAGTTTTTTTTAAGGCAAATTTGGTATAATAGTTTTAATAAGGAGGAGTTTCTCATG
ATAAAAATCTTATTGGTTGAGGATGACCTAGGTCTGTCAAATTCAGTATTTGACTTTTTAGACGATTTTG
CGGATGTTATGCAGGTATTTGATGGAGAAGAAGGTCTCTACGAAGCTGAGAGTGGTGTCTATGATTTGAT
TTTGCTGGATTTGATGTTGCCAGAAAAAAATGGTTTCCAAGTCTTAAAAGAATTGCGTGAAAAGGGAATT
ACGACACCAGTTCTGATTATGACTGCCAAGGAAAGTTTGGATGACAAGGGACATGGATTTGAACTGGGAG
CGGATGATTATCTGACCAAACCTTTCTACCTAGAAGAACTTAAAATGCGGATTCAGGCCCTTCTCAAACG
TTCAGGGAAGTTTAATGAAAACACCTTGACTTATGGGAATATCGTGGTTAATTTATCAACCAATACCGTT
AAAGTTGAAGATACTCCTGTCGAATTGCTGGGGAAAGAGTTCGATTTACTAGTTTATTTCCTTCAAAATC
AAAATGTGATTTTGCCTAAGACGCAGATTTTTGACCGTCTATGGGGATTTGATAGTGATACAACGATTTC
GGTTGTCGAAGTCTATGTTTCAAAAGTCCGTAAGAAATTAAAGGGAACCACTTTTGCAGAGAATTTGCAA
ACCTTGCGTAGTGTTGGGTATCTTTTAAAAGATGTTCAGTA
Protein Sequence 
>gi|182683717|ref|YP_001835464.1| DNA-binding response regulator CiaR [Streptococcus pneumoniae CGSP14] MQRVEFFLRQIWYNSFNKEEFLMIKILLVEDDLGLSNSVFDFLDDFADVMQVFDGEEGLYEAESGVYDLILLDLMLPEKNGFQVLKELREKGITTPVLIMTAKESLDDKGHGFELGADDYLTKPFYLEELKMRIQALLKRSGKFNENTLTYGNIVVNLSTNTVKVEDTPVELLGKEFDLLVYFLQNQNVILPKTQIFDRLWGFDSDTTISVVEVYVSKVRKKLKGTTFAENLQTLRSVGYLLKDVQ
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: ciaR mutant is attenuated in mice (Ibrahim et al., 2004).
COG COG0745TK, under T: Signal transduction mechanisms; K: Transcription
References
Ibrahim et al., 2004: Ibrahim YM, Kerr AR, McCluskey J, Mitchell TJ. Control of virulence by the two-component system CiaR/H is mediated via HtrA, a major virulence factor of Streptococcus pneumoniae. Journal of bacteriology. 2004; 186(16); 5258-5266. [PubMed: 15292127].