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mce4A from Mycobacterium tuberculosis H37Rv

Victor ID 305
Gene Name mce4A from Mycobacterium tuberculosis H37Rv
Sequence Strain (Species/Organism) Mycobacterium tuberculosis H37Rv
NCBI Gene ID 888344
NCBI Protein GI 57117113
Locus Tag Rv3499c
Protein Accession YP_177977.1
Other Database IDs UniProtKB-ID: Q7D5E7_MYCTU
UniRef100: UniRef100_A1KPI4
UniRef90: UniRef90_A1KPI4
UniRef50: UniRef50_A3Q6I7
UniParc: UPI00000D5E87
EMBL: AE000516
EMBL: BX842583
EMBL-CDS: AAK47962.1
EMBL-CDS: CAE55602.1
RefSeq_NT: NC_002755.2
RefSeq_NT: NC_000962.2
EnsemblGenome: EBMYCG00000001777.
EnsemblGenome_TRS: EBMYCT00000001779
EnsemblGenome_PRO: EBMYCP00000001779
EnsemblGenome: EBMYCG00000072529.
EnsemblGenome_TRS: EBMYCT00000072534
EnsemblGenome_PRO: EBMYCP00000070593
GenomeReviews: AE000516_GR
GenomeRev
Taxonomy ID 83332
Gene Starting Position 3917997
Gene Ending Position 3919199
Gene Strand (Orientation) -
Protein Name MCE-FAMILY PROTEIN MCE4A
DNA Sequence 
>gi|57116681:3917997-3919199 Mycobacterium tuberculosis H37Rv, complete genome
ATCAGAAGTCGTCCCGTTCCGCGAACGCACCGTTGAACAGGAACTGCAGCGTCGACGGCGCGTCAACCTG
TAACTCGGTGAACGGCTGGTATGGGATCAAAGCGTTGTCGGTGACCAGGAACGGCGCGCGGTAGAACGAC
CCGCCCGTCTGCTTGGTCGGGATATCGGGCAACCCTCGGCAGTTCGGACCGCCGGAGGCGTTGACGATCG
GCAGGCTCTCCGGATAGGTGTACGACGGCGCACCCAACACGAAGCTCGACGAGGTGAACAGCCCAGCCTT
ACGGACACCGATTAGCGGGGCAAACTCCTTGACACCGCGCGCGATGCCCTTGAAAAGGCAGCCGAATACC
GGGGAGTAGTCGGAGGTCACTTTGAGCGGGGCTCGGAGCCGGTTGATGGCGTCGATGAAATTCTGTTCGG
CGGGCGCCAACGTCTCATAGGCGTTATTAGACAGACCGATGGTGGCTAGCAGCGTGTCGTTGAGGTTGTC
CTTCTGGTCGACGATCGTCTTGTTGATCGTCGGCAGGTTATCGAACACGGTGTTCAGGTCCCCGGCGGCG
TCAGCATAGACGTTGGCCACCACCGCCGCCTTGCGGAAATCCTCCTGAAGGGCGGGTAACTTTGGGTTCG
CTTGGCGGGTCAGCGTGTTCAGTCCCGACAACAGCGCACCCAGGTCATCGCCGTGGCCGCGCAGGCCTTC
GGACAGCGCGCTCAGCGTCGCGTTCGTTTCAAGCGGATCGATCTTGTGTAGCAGGTCGATGAGCGATTGG
AACAACGTGTTGACCTCAAGCTGTACCTGAGACGCCGCCACGTGCGCATTCGGACTTAGCGGCTTGGGCG
ACGGCGTCTTTGGCGGAATGAATTCCACCGATTTGGCGCCGAAGATGGTGTTTCCGGCGATGCGCACCGT
CGCGTTGGAGGGGATAAAACCCATCTCGCCGCTGTCGATGGCCAGCTTGAGCCGTGCTTGGTTGCCGCTG
TAGCTGATATCCGTGACCTTGCCTACCTGGATGCCACGGTATTTGACCTTGGCGCCCTTCTCCATAACCA
GGCCGGCCCTCGGCGACGATACCGTGACGGTGTCCGTAGACGTGAAAGCCGCCGTATACGAAAGATAAGT
CAGCACTGCGGATCCCACCATCAGCCCGGCCAGCAGCGCCGCTGCCACCCTGACACTGGTGCGTCGAGAT
CCGCCGCCGGACA
Protein Sequence 
>gi|57117113|ref|YP_177977.1| Mce family protein Mce4A [Mycobacterium tuberculosis H37Rv] MSGGGSRRTSVRVAAALLAGLMVGSAVLTYLSYTAAFTSTDTVTVSSPRAGLVMEKGAKVKYRGIQVGKVTDISYSGNQARLKLAIDSGEMGFIPSNATVRIAGNTIFGAKSVEFIPPKTPSPKPLSPNAHVAASQVQLEVNTLFQSLIDLLHKIDPLETNATLSALSEGLRGHGDDLGALLSGLNTLTRQANPKLPALQEDFRKAAVVANVYADAAGDLNTVFDNLPTINKTIVDQKDNLNDTLLATIGLSNNAYETLAPAEQNFIDAINRLRAPLKVTSDYSPVFGCLFKGIARGVKEFAPLIGVRKAGLFTSSSFVLGAPSYTYPESLPIVNASGGPNCRGLPDIPTKQTGGSFYRAPFLVTDNALIPYQPFTELQVDAPSTLQFLFNGAFAERDDF
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: attenuated in mice (Sassetti and Rubin, 2003).
COG COG1463Q, under Q: Secondary metabolites biosynthesis, transport and catabolism
References
Sassetti and Rubin, 2003: Sassetti CM, Rubin EJ. Genetic requirements for mycobacterial survival during infection. Proceedings of the National Academy of Sciences of the United States of America. 2003; 100(22); 12989-12994. [PubMed: 14569030].