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pgdA from Streptococcus pneumoniae CGSP14

Victor ID 3048
Gene Name pgdA from Streptococcus pneumoniae CGSP14
Sequence Strain (Species/Organism) Streptococcus pneumoniae CGSP14
NCBI Gene ID 6217943
NCBI Protein GI 182684437
Locus Tag SPCG_1467
Protein Accession YP_001836184.1
Other Database IDs UniProtKB-ID: B2IQU5_STRPS
UniRef100: UniRef100_B2IQU5
UniRef90: UniRef90_Q04JM3
UniRef50: UniRef50_Q04JM3
UniParc: UPI00016C28A9
EMBL: CP001033
EMBL-CDS: ACB90719.1
RefSeq_NT: NC_010582.1
EnsemblGenome: EBSTRG00000017007.
EnsemblGenome_TRS: EBSTRT00000017007
EnsemblGenome_PRO: EBSTRP00000016321
GenomeReviews: CP001033_GR
KEGG: spw:SPCG_1467
HOGENOM: HBG703418
OMA: AHELYYS
ProtClustDB: CLSK884105
Taxonomy ID 516950
Gene Starting Position 1442747
Gene Ending Position 1444189
Gene Strand (Orientation) -
Protein Name peptidoglycan N-acetylglucosamine deacetylase A
DNA Sequence 
>gi|182682970:1442747-1444189 Streptococcus pneumoniae CGSP14, complete genome
CTTATTCATCACGACTATAGTACAGCTCATGAGCTTTTAGGCGAGTATTGAGCATCTCTGGTATGGTCAC
AAAGGTATAACCTTGATTTTTCAAATACTCAATGACCCTTGGCAAGGCATTGACTGTCGGACTGTGAATA
TCATGCATCAAAACGATAGAGCCGTTAGCTACTTGATGCTGAATTTCTGTCAAAATAGATGCTTCATTTT
TACTCTTCCAGTCCAGACTATCCACATCCCACATGATAAAGCTCAAATCCAAGCTATTGCGAATATCATC
TGTAATAGCACCATAAGGTGGACGCATGAGTTTAGAACTAGAACCCAGCACTTTAGTTAGCACATCCTCA
GTATCAGTAATCTGCTTTTTAGCTTCATCAAGAGAGAGTTGCGAGAGAATCGGATGGCTCCAACTATGGT
TTCCAACAACATGACCTTCAGATTTTATCCTCTTCACCAAGTCCTCATTCCCAGAAACATTTTTCCCAAG
CACAAAGAAAGTCGCTTTAATATCATATTTAGCTAGGGTCTCTAATACCTGCGGGGTCGTTGCTGGATTT
GGACCATCATCAAAGGTTAGAGCGACAACTTTTTGATATTTCTTATCAAAGTAAGATTGGTACAAGGCCG
CATCTTTTTCGAGTAAGTACGAAGATTGGATAACATCAAAGAAAGCAGATACTGGCAAGGCTATCTCTTC
TAAATTTTCAACCACAGGACTTGGATAAAGGATAATCTGACTATCCTTGTAATCAAAATTCCATGCAGAC
AAGTCTTGGTCAGAGAAGTTTTTTACAATCTGCTCACTCTGGTCTTGCTCTATTTTTTTATCCTCTATGA
AGGAGGTCAACTCTTTTATCAGCTGTTCCTTAGCCTTACTAGCATCTGAAAACAGTTGGTCAAGTGTAAA
AGGTTGCCCATCTTCTGTTAAGTGAACCTTTCCTAGACTGGTCTTTTCAGTCTCTTCAACCTTAAAAGCA
ACTAAATCATAGATTTGTTTGGTCACATTACGATTAACGACTCCCTTTAAACCTGACTCTTCTTGCTCTG
TATAGTAGAAAACAAGATTGTCCTTACTTTCTAGCTTGTCCTTAACATCTTGATTTATCAACTCCCTAAC
AGAGGAAATCACTTTCTCCCCTTGGAGAGGATAATAGGCAATCACTTCGGCTTGCCCCTGACGAAAATGC
TCCTTCTGATTTCCCTCACTCAATTGATCATCTTTCTCTTTTTTGAGCGATTCAATCTTTTGCTCAAAAC
TTTTTTGCTGGTAGATCTTAAAAGCAATAAATCCGCCTAATAGGCAAATAGAAATTGCTAAAATACCAAT
CAAAGCCAATAATACATGTCTCGTTTTCCCGTGTCTGCCACGTCCTAGTCTACTTTTATTCATATTTATA
TCATAACAAATTTGAGCAATAATTTCAATGATACAATTTGGCA
Protein Sequence 
>gi|182684437|ref|YP_001836184.1| peptidoglycan N-acetylglucosamine deacetylase A [Streptococcus pneumoniae CGSP14] MPNCIIEIIAQICYDINMNKSRLGRGRHGKTRHVLLALIGILAISICLLGGFIAFKIYQQKSFEQKIESLKKEKDDQLSEGNQKEHFRQGQAEVIAYYPLQGEKVISSVRELINQDVKDKLESKDNLVFYYTEQEESGLKGVVNRNVTKQIYDLVAFKVEETEKTSLGKVHLTEDGQPFTLDQLFSDASKAKEQLIKELTSFIEDKKIEQDQSEQIVKNFSDQDLSAWNFDYKDSQIILYPSPVVENLEEIALPVSAFFDVIQSSYLLEKDAALYQSYFDKKYQKVVALTFDDGPNPATTPQVLETLAKYDIKATFFVLGKNVSGNEDLVKRIKSEGHVVGNHSWSHPILSQLSLDEAKKQITDTEDVLTKVLGSSSKLMRPPYGAITDDIRNSLDLSFIMWDVDSLDWKSKNEASILTEIQHQVANGSIVLMHDIHSPTVNALPRVIEYLKNQGYTFVTIPEMLNTRLKAHELYYSRDE
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: pgdA mutant is attenuated in mice (Vollmer and Tomasz, 2002).
COG COG0726G, under G: Carbohydrate transport and metabolism
References
Vollmer and Tomasz, 2002: Vollmer W, Tomasz A. Peptidoglycan N-acetylglucosamine deacetylase, a putative virulence factor in Streptococcus pneumoniae. Infection and immunity. 2002; 70(12); 7176-7178. [PubMed: 12438406].