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cbpD from Streptococcus pneumoniae CGSP14

Victor ID 3044
Gene Name cbpD from Streptococcus pneumoniae CGSP14
Sequence Strain (Species/Organism) Streptococcus pneumoniae CGSP14
NCBI Gene ID 6217546
NCBI Protein GI 182685138
Locus Tag SPCG_2168
Protein Accession YP_001836885.1
Other Database IDs UniProtKB-ID: B2INL9_STRPS
UniRef100: UniRef100_B1IA13
UniRef90: UniRef90_B1IA13
UniRef50: UniRef50_Q8DMZ4
UniParc: UPI00016C2C7A
EMBL: CP001033
EMBL-CDS: ACB91420.1
RefSeq_NT: NC_010582.1
EnsemblGenome: EBSTRG00000017232.
EnsemblGenome_TRS: EBSTRT00000017232
EnsemblGenome_PRO: EBSTRP00000016546
GenomeReviews: CP001033_GR
KEGG: spw:SPCG_2168
HOGENOM: HBG702133
OMA: RVIKANT
ProtClustDB: CLSK803921
Taxonomy ID 516950
Gene Starting Position 2169758
Gene Ending Position 2171104
Gene Strand (Orientation) -
Protein Name choline binding protein D
DNA Sequence 
>gi|182682970:2169758-2171104 Streptococcus pneumoniae CGSP14, complete genome
TCTATACTCGTTCTCCATCACTGTTTACTCTGTAGCCATCCACCGTCGTATTAACAGCTAAGGCGCCTGA
AGAGTAAGAATAATACCACTTACCAGAGACCTGGTACCAGCCTGTTTTCATTGCCCCTGAACTACCCAGA
TAATACCACGAGCCATTCTCCTTTAACCATCCTGTCTGCATTTCACCAGATAATTTCAAATAATACCAGC
TAGAACCGTCTTTCAGCCATCCTGTTGATTTAGAACCATTTGATTTGAAATGATACCAACTACCATTTAT
TTTCTTCCAACCGACAGTTGAACTATTATTGGATCCATAGCTAGAGATATTTCCTGATTGATTCTGATAA
TTTTGTGAAGAAGTCACTCCCTCTAGCTGTATATAGCGACGACTTCCGTTATAAGCCGTATAACTCAACC
ACTTGTAGCCGTCTTTTTCAAGTATCTGATCATAATGAACCTTCTCCCCAGGATAATAGTAATCAATCAC
AGTTGCACTAACTAGGGGTTCAGTTTTGATAGCAGACTTGGTCTTAAAATAATGAGTTCCACCTGTTGAA
GAAAGAACAGAATTACCTAGAGGATTTTTATTCACAGCCTCCAATTGAACATAACGATAGCTTCCATTAT
AGGCAGTATAACTCAACCACTTGTAGCCGTCTTTTTCGAGAATTTGATCATAATGAACCTTCTCTCCAGG
ATAATAGTAATCAATCACAGTTGCACTAACTAGGGGTTCAGTTTTAATAGCAGACTTGGTCTTAAAATAA
TGAGTTCCGCCTGTTGAAGTTGAGGATTGACTATTCCCAACACTGCCACCATCCAAATCTTTAAAATGAA
TAAATCCTGTCATCGTGTTTGCTTTTATAATTCGTTTATTATAGGATTCTGTATAACCATAGTTATATTC
CTCAATCTCAATCTGATCTCCCATTACATTTGACACCCAGGCAACATGACCATAAGTTCCTGCAGTAGAC
CAAGTAATGGAACCAATCGTCGGTGTATTATCTACACGATAACCTTCCCGACGAGCACGATGTCCCCATT
CATTCGCATTTCCATAAGCTGCCGGAATTTCAAAACCATTGACATTACTCAAACGAAAGGCTACAAAAGA
AGTACATTGACGAGAATACATGCGCCACTGATCAATCTCCTGGCTCCCATTTTTATAATAAGCAGGATAA
TCATCCCCACGCGCAATCGATCCATTTCCTCTGGAATAGGCATAGACACTATCACCAGCTGCTAGCATCA
ATCCTACTACTAAAAAAGGAACAAGCTTTTTAACTGACATCTTCAAGTAATAACTTGTTCCTCTTGCTAT
AAACGGTAAAATTTTCA
Protein Sequence 
>gi|182685138|ref|YP_001836885.1| choline binding protein D [Streptococcus pneumoniae CGSP14] MKILPFIARGTSYYLKMSVKKLVPFLVVGLMLAAGDSVYAYSRGNGSIARGDDYPAYYKNGSQEIDQWRMYSRQCTSFVAFRLSNVNGFEIPAAYGNANEWGHRARREGYRVDNTPTIGSITWSTAGTYGHVAWVSNVMGDQIEIEEYNYGYTESYNKRIIKANTMTGFIHFKDLDGGSVGNSQSSTSTGGTHYFKTKSAIKTEPLVSATVIDYYYPGEKVHYDQILEKDGYKWLSYTAYNGSYRYVQLEAVNKNPLGNSVLSSTGGTHYFKTKSAIKTEPLVSATVIDYYYPGEKVHYDQILEKDGYKWLSYTAYNGSRRYIQLEGVTSSQNYQNQSGNISSYGSNNSSTVGWKKINGSWYHFKSNGSKSTGWLKDGSSWYYLKLSGEMQTGWLKENGSWYYLGSSGAMKTGWYQVSGKWYYSYSSGALAVNTTVDGYRVNSDGERV
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: cbpD has reduced colonization of nasopharynx of rats compared to the wild type (Gosink et al., 2000).
COG COG3942R, under R: General function prediction only
References
Gosink et al., 2000: Gosink KK, Mann ER, Guglielmo C, Tuomanen EI, Masure HR. Role of novel choline binding proteins in virulence of Streptococcus pneumoniae. Infection and immunity. 2000; 68(10); 5690-5695. [PubMed: 10992472].