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pspC from Streptococcus pneumoniae CGSP14

Victor ID 3042
Gene Name pspC from Streptococcus pneumoniae CGSP14
Sequence Strain (Species/Organism) Streptococcus pneumoniae CGSP14
NCBI Gene ID 6217403
NCBI Protein GI 182685128
Locus Tag SPCG_2158
Protein Accession YP_001836875.1
Other Database IDs UniProtKB-ID: B2INK9_STRPS
UniRef100: UniRef100_B2INK9
UniRef90: UniRef90_B2INK9
UniRef50: UniRef50_B2INK9
UniParc: UPI000172BB1A
EMBL: CP001033
EMBL-CDS: ACB91410.1
RefSeq_NT: NC_010582.1
EnsemblGenome: EBSTRG00000016580.
EnsemblGenome_TRS: EBSTRT00000016580
EnsemblGenome_PRO: EBSTRP00000015894
GenomeReviews: CP001033_GR
KEGG: spw:SPCG_2158
HOGENOM: HBG702376
OMA: PENPAEQ
ProtClustDB: CLSK559743
Taxonomy ID 516950
Gene Starting Position 2158220
Gene Ending Position 2160382
Gene Strand (Orientation) -
Protein Name choline binding protein A
DNA Sequence 
>gi|182682970:2158220-2160382 Streptococcus pneumoniae CGSP14, complete genome
TTTAGTTTACCCATTCACCATTGGCATTGACTCTATAGCCATCTACAGTTGTGTTGACTGCAAGGGCACC
TAAGCCATTGACATAGTACCATTTATCTGATACTTTGAACCATTGGCTTGCTTTCATAGCACCTGATGCT
TCAAGATAGTACCAGGTATCTCCATCTTTCACCCAATCTGTTGCCATTGAACCGTTAGCGTTGAGGTAGT
ACCATGAACCATTGTATTGGAGCCATCCTGTCGCCATATCACCATTAGCGTTGAGGTAGTACCATGAACC
ATTGTATTGGAGCCATCCTGTCGCCATATCACCATTAGCGTTGAGGTAGTACCATGAACCATTGTATTGG
AGCCATCCTGTCGCCATATCACCATTAGCGTTGAGGTAGTACCATGAACCATTGTATTGGAGCCATCCTG
TCGCCATATCACCATTAGCGTTGAGGTAGTACCATGAACCATTGTATTGGAGCCATCCTGTCGCCATATC
ACCATTAGCGTTGAGGTAGTACCATGAACCATTGTATTGGAACCATCCTGTCGCCATTGAACCATTAGCG
TTTAGATAGTACCATGAACCATTGTTTTGGAGCCATCCTGTCGCCATAGCGCCATTGCTGTTGAGGTAGT
ACCATGAACCATTGTTTTGGAGCCATCCTGTCGCCATTGAACCATCAGTATTGTAGAAGTACCACATACC
GTTTTCTTGTTTCCAGCCTGTTTTTGGAGTAGATGGTTGTGCTGGTTTTTCAGTTTTTGGCGGTTGCTGT
TGAGTCAAGCGATTATATTCTTCTTCTGATCTACGAGCATAGTCTTCTTCAGCTTGTTGATCAGCTGGTT
TTTCTGCTTTTGGTTGTTCAGCTGGATTCTCTGGTTTTGGAGCTGGTTTTTCTGGTTGAGGAGCCGGCGC
TGGTTGTGGTTGTTCAGCTGGTTTTTCTTTAACTTTATCTTCTTCTGCTGCTTTTCGTTTAGCTTCTTCT
TCTGCTTTTTTACGATCTGTCTTGATGTTTTCTAACCTTGTAGCCTCAGCTTTTTTACTCTCAACTTTCG
CTTTTGCTTGCTTAATTTTTTCCTCGTTTTGAGATTCCTTAGCTTCCTCTTTTACTAGTTCAAGCTCCGC
TTCTTTAACTTTCACATCGGACTCAGCAATTTCAAGTTCAAGCGTTTTGTAAGTATTGGTTGGGTAGTTA
CGGCGATCTTCTTCTTTTTGATCCTTGGCTTTTTTCTTAGCTTCTTCAACCTTCTTCTGAGCTTCTGCTA
CCTTTTTTCCTGGTTTCAGGGATGGGCTTGGAAGAGTTTCTTCACCTACGCTAGAATCTGAAGACTTCGC
ATCATTTTCTTTTTTATCAGGTGTTGCTTGCTCTCCAAGATCTCCTCGTTTTACCCGACTCTTTCGCCTC
TTTGATTCATCTTGCTCTTTAGCATCTGCTCTTCGTTTAGCTTCTTCTTCTGCTTTTTCACGATCTGTCT
TGATTTTTTTTAACCTTGTAGCCTCAGCTTTTTCACTCTCAACTTTCGCTTTTGCTTGGTTAATTGTGCC
CTCGTTTCGAGATTCGTCAGCTTCCTTTTTTACTAGTTCAAGCTCCGCTTCTTTAACTTTCACATCGAAC
TCAGCAATTTCAAGTTCAAGCGTTTTGTAAGTAATGGTTGGGTAGTTACGGTAATCTTCTTCTTTTTGAG
CCTTGGCTTTTTTCTTAGCTTCTGCTACCTTCTTCTCAGCTTCTTCAACCTTCTTCTTAGCTTCTGCTAC
CTTTTTTCCTGGTTCTGTTGGTAATGTATCTTTTTTAAACTGCTCAAAAGCTGCGGTTAACTCTTCTTTT
ATTTTTGGCGGCAACTCATCTTTCGACTTCTCTTCTAAAACATTTAATTCACGCAAATACTTCGTTTTAA
TTGCGCTCAACTTTATGATTAAGGTGCGATTTTGGGTATCTTTTCTTCTATCTAATTGGATCATTTTGTT
TATATATTCATCGAATTGTTTAGCAGCTTTCCTATGTTCTGTCTTTGCCATATTAGAAGAAGTGGCTGCT
TGGGTACTTCCCTCTTTCTCTGTCGCATGAACCACACTTCCCATAAAAAGACTGGCAACAGCTACACTAG
CTACTCCAATACTAAATTTACGAATTGAATAATGTACTTTTCTTTCGCTTTTTGATGCAAACA
Protein Sequence 
>gi|182685128|ref|YP_001836875.1| choline binding protein A [Streptococcus pneumoniae CGSP14] MFASKSERKVHYSIRKFSIGVASVAVASLFMGSVVHATEKEGSTQAATSSNMAKTEHRKAAKQFDEYINKMIQLDRRKDTQNRTLIIKLSAIKTKYLRELNVLEEKSKDELPPKIKEELTAAFEQFKKDTLPTEPGKKVAEAKKKVEEAEKKVAEAKKKAKAQKEEDYRNYPTITYKTLELEIAEFDVKVKEAELELVKKEADESRNEGTINQAKAKVESEKAEATRLKKIKTDREKAEEEAKRRADAKEQDESKRRKSRVKRGDLGEQATPDKKENDAKSSDSSVGEETLPSPSLKPGKKVAEAQKKVEEAKKKAKDQKEEDRRNYPTNTYKTLELEIAESDVKVKEAELELVKEEAKESQNEEKIKQAKAKVESKKAEATRLENIKTDRKKAEEEAKRKAAEEDKVKEKPAEQPQPAPAPQPEKPAPKPENPAEQPKAEKPADQQAEEDYARRSEEEYNRLTQQQPPKTEKPAQPSTPKTGWKQENGMWYFYNTDGSMATGWLQNNGSWYYLNSNGAMATGWLQNNGSWYYLNANGSMATGWFQYNGSWYYLNANGDMATGWLQYNGSWYYLNANGDMATGWLQYNGSWYYLNANGDMATGWLQYNGSWYYLNANGDMATGWLQYNGSWYYLNANGDMATGWLQYNGSWYYLNANGSMATDWVKDGDTWYYLEASGAMKASQWFKVSDKWYYVNGLGALAVNTTVDGYRVNANGEWVN
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: pspC mutant is has reduced ability to colonize nasopharynx of mice compared to the wild type (Ogunniyi et al., 2007).
COG COG5263R, under R: General function prediction only
References
Ogunniyi et al., 2007: Ogunniyi AD, LeMessurier KS, Graham RM, Watt JM, Briles DE, Stroeher UH, Paton JC. Contributions of pneumolysin, pneumococcal surface protein A (PspA), and PspC to pathogenicity of Streptococcus pneumoniae D39 in a mouse model. Infection and immunity. 2007; 75(4); 1843-1851. [PubMed: 17261599].