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luxS from Streptococcus pneumoniae CGSP14

Victor ID 3039
Gene Name luxS from Streptococcus pneumoniae CGSP14
Sequence Strain (Species/Organism) Streptococcus pneumoniae CGSP14
NCBI Gene ID 6217141
NCBI Protein GI 182683313
Locus Tag SPCG_0343
Protein Accession YP_001835060.1
Other Database IDs UniProtKB-ID: LUXS_STRPS
UniRef100: UniRef100_B8ZL57
UniRef90: UniRef90_Q04MC2
UniRef50: UniRef50_Q1JAI5
UniParc: UPI000172AFBC
EMBL: CP001033
EMBL-CDS: ACB89595.1
RefSeq_NT: NC_010582.1
EnsemblGenome: EBSTRG00000017680
EnsemblGenome_TRS: EBSTRT00000017680
EnsemblGenome_PRO: EBSTRP00000016994
GenomeReviews: CP001033_GR
KEGG: spw:SPCG_0343
HOGENOM: HBG347473
OMA: VRIAKTM
ProtClustDB: PRK02260
Taxonomy ID 516950
Gene Starting Position 334125
Gene Ending Position 334607
Gene Strand (Orientation) -
Protein Name S-ribosylhomocysteinase
DNA Sequence 
>gi|182682970:334125-334607 Streptococcus pneumoniae CGSP14, complete genome
TTTAAATCACATGACGTTCAAAGGCATCATCTGAAATCCCTTGTTCCAAGATGAGTCTTGCCCATTCTTT
AGCAGAGAAGAGGCTGTGGTCCTTGTAGTTTCCGCAAGATTCGATGGTTGTCCCTGGGACATCTTCCCAA
GTAGTAGTTTCAGCGATTTCCTTGAGCGAATCCTTGATAACAGCTGCGATTTTAGCACTGGTGTGACGTC
CCCACATAATCATGTGGAAGCCTGTGCGACAACCAAATGGTGAACAGTCAATCATGCCGTCAATGCGGGT
ACGGATGAGTTTGGCTAAGAGGTGCTCGATAGTGTGAAGGCCGGCAGTAGGGATAGAGTCTTCGTTTGGT
TGCACCAAGCGAATATCATAATTGGAGATGATGTCTCCTTTTGGTCCTGTTTCTTCCCCAATCAAGCGAA
CATAGGGTGCTTTGACAATGGTGTGGTCAAGTTCAAAACTTTCGACAATAACTTCTTTTGACA
Protein Sequence 
>gi|182683313|ref|YP_001835060.1| S-ribosylhomocysteinase [Streptococcus pneumoniae CGSP14] MSKEVIVESFELDHTIVKAPYVRLIGEETGPKGDIISNYDIRLVQPNEDSIPTAGLHTIEHLLAKLIRTRIDGMIDCSPFGCRTGFHMIMWGRHTSAKIAAVIKDSLKEIAETTTWEDVPGTTIESCGNYKDHSLFSAKEWARLILEQGISDDAFERHVI
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: luxS mutant has defective ability to persist in the nasopharyngeal tissues of mice (Joyce et al., 2004).
COG COG1854T, under T: Signal transduction mechanisms
References
Joyce et al., 2004: Joyce EA, Kawale A, Censini S, Kim CC, Covacci A, Falkow S. LuxS is required for persistent pneumococcal carriage and expression of virulence and biosynthesis genes. Infection and immunity. 2004; 72(5); 2964-2975. [PubMed: 15102809].