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nox from Streptococcus pneumoniae CGSP14

Victor ID 3036
Gene Name nox from Streptococcus pneumoniae CGSP14
Sequence Strain (Species/Organism) Streptococcus pneumoniae CGSP14
NCBI Gene ID 6216649
NCBI Protein GI 182684428
Locus Tag SPCG_1458
Protein Accession YP_001836175.1
Other Database IDs UniProtKB-ID: B2IQT6_STRPS
UniRef100: UniRef100_B2IQT6
UniRef90: UniRef90_B2IQT6
UniRef50: UniRef50_A2RIB7
UniParc: UPI00000B9663
EMBL: CP001033
EMBL-CDS: ACB90710.1
RefSeq_NT: NC_010582.1
EnsemblGenome: EBSTRG00000018520.
EnsemblGenome_TRS: EBSTRT00000018520
EnsemblGenome_PRO: EBSTRP00000017834
GenomeReviews: CP001033_GR
KEGG: spw:SPCG_1458
HOGENOM: HBG535576
OMA: FFFQPHF
ProtClustDB: CLSK877163
Taxonomy ID 516950
Gene Starting Position 1432280
Gene Ending Position 1433659
Gene Strand (Orientation) -
Protein Name NADH oxidase
DNA Sequence 
>gi|182682970:1432280-1433659 Streptococcus pneumoniae CGSP14, complete genome
TTTATTTTTCAGCCGTAAGGGCAGCCATTGTGATGTAGTTGTATGGTTTGTTGAAGTGTGGCAAGAAGAA
GAGGTCTGTCAATGCCAATTTATCAATTGTCACATGCTCTTGGATAGCAAGTGAGAACATGTGGATTCCC
ATGCTAATTGCAATATCATGGGAAACCATTTGGGCACCAAGAATTTCACGGCTATCTTTGTCAAAGACAA
TCTTAATTGCTACTTCATGGTTGTCATGTTTCATGAATTCTGGTTTTTGAAGATCGTTAAAGCCTGTTTC
AGTTGCGTTGTAACCAGCAGCTTTCGCTTTTTCAAGAGTCAAACCAGTTGAAACCATGTGAAGACCGTAG
ATTGAGATACCATTTGAACCTTGAACACCGATTCCTTCCAATTCATGTCCACAAGCGTTGTAGGCACCAA
CGATACCAGTGCGAACAGCATTTGAAGCAAGAGCGATATAGCTTGTATCTTTACGAGCATTGTCATAAAC
AGTCGCACAGTCACCAACAGCGTAAACGCCTGGGATAGATGTTTCTTGTTTCTTGTCTACAAGGAAGGCA
CCGTTGCGGAAGAGTTCGATCTTACCATCTGCAAGGGCTGTGTTTGGACGGAAACCAACTGCAAGGATAA
CCATATCCACGTCAAAGCTTTCTTTGTCAGTAATCAAGCGTTCAACTTTACCGTCACCTTCGATTGCTTT
AACAGTTTGACCTAGAGCCAAGCGGATGTTGTGATCTTCCAAGTTCTTCGCCATCATTTGTGTGAAGTCT
TTGTCATAGTAACCGTTCAAGACAGTATCAACGATATCAACAAGGACAACTTCTTTTCCAAGACGTTCAA
AGGCTTCAGCAAGTTCAACACCGATGTAACCACCACCAACAACGGCGATACGGTCGAGGTGTTGGCTCTT
GTCAGAAAGTTTATTGATAACTTCTTCAGCATTTTGGTACAATTTCACGAATTGTACGTTTTCAAGAGTT
GCTTTAAATTCGCGGTTTCCTTTAACAATTTCAACACCTTCGATTGGTGGCAAGATTGGTGTAGAACCTG
TAGCGAAAATCAATTTTTCGTATGATTCTTTGTGCTCTTTTCCTTCAACTTCCGCTGTAACTACTTTGTT
ATCATAGTCGATTGAAAGAACAGGTGAGTTCATGTAAACTTTAGCACCTTTAGCTTCCAATTTTTCTTTA
TCAGAATAGAACAAGCCTTCAGCACCGTCAATTTGTTCACCAATCCAAAGAGCCATTCCACATCCTAGGA
AAGAGATGTTAGAGTTTTGGTCAAATACAACAATTTCGTTCTCATTTCCAAAATTATCCAACATGGTATT
GATACATGCTGTACCAGCGTGGTTAGCACCGACTACAACGATTTTACTCA
Protein Sequence 
>gi|182684428|ref|YP_001836175.1| NADH oxidase [Streptococcus pneumoniae CGSP14] MSKIVVVGANHAGTACINTMLDNFGNENEIVVFDQNSNISFLGCGMALWIGEQIDGAEGLFYSDKEKLEAKGAKVYMNSPVLSIDYDNKVVTAEVEGKEHKESYEKLIFATGSTPILPPIEGVEIVKGNREFKATLENVQFVKLYQNAEEVINKLSDKSQHLDRIAVVGGGYIGVELAEAFERLGKEVVLVDIVDTVLNGYYDKDFTQMMAKNLEDHNIRLALGQTVKAIEGDGKVERLITDKESFDVDMVILAVGFRPNTALADGKIELFRNGAFLVDKKQETSIPGVYAVGDCATVYDNARKDTSYIALASNAVRTGIVGAYNACGHELEGIGVQGSNGISIYGLHMVSTGLTLEKAKAAGYNATETGFNDLQKPEFMKHDNHEVAIKIVFDKDSREILGAQMVSHDIAISMGIHMFSLAIQEHVTIDKLALTDLFFLPHFNKPYNYITMAALTAEK
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: nox mutant is attenuated in mice (Yu et al., 2001).
COG COG0446R, under R: General function prediction only
References
Yu et al., 2001: Yu J, Bryant AP, Marra A, Lonetto MA, Ingraham KA, Chalker AF, Holmes DJ, Holden D, Rosenberg M, McDevitt D. Characterization of the Streptococcus pneumoniae NADH oxidase that is required for infection. Microbiology (Reading, England). 2001; 147(Pt 2); 431-438. [PubMed: 11158360].