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regR from Streptococcus pneumoniae CGSP14

Victor ID 3034
Gene Name regR from Streptococcus pneumoniae CGSP14
Sequence Strain (Species/Organism) Streptococcus pneumoniae CGSP14
NCBI Gene ID 6216376
NCBI Protein GI 182683304
Locus Tag SPCG_0334
Protein Accession YP_001835051.1
Other Database IDs UniProtKB-ID: B2ISP9_STRPS
UniRef100: UniRef100_B2ISP9
UniRef90: UniRef90_B2ISP9
UniRef50: UniRef50_D6ZQH0
UniParc: UPI00000513C3
EMBL: CP001033
EMBL-CDS: ACB89586.1
RefSeq_NT: NC_010582.1
EnsemblGenome: EBSTRG00000018721.
EnsemblGenome_TRS: EBSTRT00000018721
EnsemblGenome_PRO: EBSTRP00000018035
GenomeReviews: CP001033_GR
KEGG: spw:SPCG_0334
HOGENOM: HBG753640
OMA: ISISRRC
ProtClustDB: CLSK797399
Taxonomy ID 516950
Gene Starting Position 323900
Gene Ending Position 324967
Gene Strand (Orientation) +
Protein Name sugar binding transcriptional regulator RegR
DNA Sequence 
>gi|182682970:323900-324967 Streptococcus pneumoniae CGSP14, complete genome
AGTGCTAGAAATAGGCATTTTGAATAGTGAATATGTTATAATAAGTATTAGTAGGAGGTGTTTTAGATTG
GAGAAGAAACTGACCATAAAAGACATTGCGGAAATGGCTCAGACCTCGAAAACAACCGTGTCATTTTACC
TAAACGGGAAATATGAAAAAATGTCCCAAGAGACACGTGAAAAGATTGAAAAAGTTATTCATGAAACAAA
TTACAAACCGAGCATTGTTGCGCGTAGCTTAAACTCCAAACGAACAAAATTAATCGGTGTTTTGATCGGT
GATATTACCAACAGTTTCTCAAACCAAATTGTTAAGGGAATTGAGGATATCGCCAGCCAGAATGGCTACC
AGGTAATGATAGGAAATAGTAATTACAGCCAAGAGAGTGAGGACCGGTATATTGAAAGCATGCTTCTCTT
GGGAGTAGACGGCTTTATTATTCAGCCGACCTCTAATTTCCGAAAATATTCTCGTATCATCGATGAGAAA
AAGAAGAAAATGGTCTTTTTTGATAGTCAGCTCTATGAACACCGGACTAGCTGGGTTAAAACCAATAACT
ATGATGCCGTTTATGACATGACCCAGTCCTGTATCGAAAAAGGTTATGAACATTTTCTCTTGATTACAGC
GGATACGAGTCGTTTGAGTACTCGGATTGAGCGGGCAAGTGGTTTTGTGGATGCTTTAACAGATGCTAAT
ATGCGTCACGCCAGTCTAACCATTGAAGATAAGCATACGAATTTGGAACAAATTAAGGAATTTTTACAAA
AAGAAATCGATCCCGATGAAAAAACTCTGGTATTTATCCCTAACTGTTGGGCCCTACCTCTAGTCTTTAC
CGTTATCAAAGAGTTGAATTATAACTTGCCACAAGTTGGGTTGATTGGTTTTGACAATACGGAGTGGACT
TGCTTTTCTTCTCCAAGTGTTTCGACGCTGGTTCAGCCCTCCTTTGAGGAAGGACAACAGGCTACAAAGA
TTTTGATTGATCAGATTGAAGGCCGCAATCAAGAAGAAAGGCAACAAGTCTTGGATTGTAGTGTGAATTG
GAAAGAGTCGACTTTCTA
Protein Sequence 
>gi|182683304|ref|YP_001835051.1| sugar binding transcriptional regulator RegR [Streptococcus pneumoniae CGSP14] MLEIGILNSEYVIISISRRCFRLEKKLTIKDIAEMAQTSKTTVSFYLNGKYEKMSQETREKIEKVIHETNYKPSIVARSLNSKRTKLIGVLIGDITNSFSNQIVKGIEDIASQNGYQVMIGNSNYSQESEDRYIESMLLLGVDGFIIQPTSNFRKYSRIIDEKKKKMVFFDSQLYEHRTSWVKTNNYDAVYDMTQSCIEKGYEHFLLITADTSRLSTRIERASGFVDALTDANMRHASLTIEDKHTNLEQIKEFLQKEIDPDEKTLVFIPNCWALPLVFTVIKELNYNLPQVGLIGFDNTEWTCFSSPSVSTLVQPSFEEGQQATKILIDQIEGRNQEERQQVLDCSVNWKESTF
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: regR mutant is attenuated in mice (Chapuy-Regaud et al., 2003).
COG COG1609K, under K: Transcription
References
Chapuy-Regaud et al., 2003: Chapuy-Regaud S, Ogunniyi AD, Diallo N, Huet Y, Desnottes JF, Paton JC, Escaich S, Trombe MC. RegR, a global LacI/GalR family regulator, modulates virulence and competence in Streptococcus pneumoniae. Infection and immunity. 2003; 71(5); 2615-2625. [PubMed: 12704136].