Victors

iga from Streptococcus pneumoniae CGSP14
Victor ID	3033
Gene Name	iga from Streptococcus pneumoniae CGSP14
Sequence Strain (Species/Organism)	Streptococcus pneumoniae CGSP14
NCBI Gene ID	6216375
NCBI Protein GI	182684113
Locus Tag	SPCG_1143
Protein Accession	YP_001835860.1
Other Database IDs	UniProtKB-ID: B2IPX1_STRPS UniRef100: UniRef100_B2IPX1 UniRef90: UniRef90_B2IPX1 UniRef50: UniRef50_Q59986 UniParc: UPI000172BB03 EMBL: CP001033 EMBL-CDS: ACB90395.1 RefSeq_NT: NC_010582.1 MEROPS: M26.001 EnsemblGenome: EBSTRG00000016784. EnsemblGenome_TRS: EBSTRT00000016784 EnsemblGenome_PRO: EBSTRP00000016098 GenomeReviews: CP001033_GR KEGG: spw:SPCG_1143 HOGENOM: HBG703220 OMA: IVEPEKV ProtClustDB: CLSK883904
Taxonomy ID	516950
Gene Starting Position	1119877
Gene Ending Position	1125603
Gene Strand (Orientation)	-
Protein Name	immunoglobulin A1 protease
DNA Sequence	>gi\|182682970:1119877-1125603 Streptococcus pneumoniae CGSP14, complete genome ACTATTTTTTATTCTCAAAAATTGAACTTCTAAAATCATTTGTTTGGTCAAGATAAGCTTTATATATTGC TTTTTTCAGTTTAAGAACTCTACTATTTGTTTCTGGGTAAAATTTTGCTACGTCATCTTGCGCATCATCT CTCACTGCTTCGACAATCATTCTCTCTAGTACACCTATATCCGTAACCGATACATTTCGTTGACGACTCA ATGGATTATTAGGATTAATAAAGTTAACTCTATTTAGTTTACTGAATTGTTTTTCTCTTTCCTTATACAT ATCCTTCTTGAATTGTGTCCAAGTTTTATATTGACCATTAAATACTTTTTCAAGTACTAATTCATCTGTA ACTAAACCTACTTCTTTACCATAAGAATTAATCTTACTTCCCGCCGCTTTTGCATCTTTTTCATATTGAT TTGAGATATAAGGTACCATGCCCTCTTTATATCCTTTTGCAGCTAATAATTCGAATGCTATACGGCGTCC CATTAAATCACCAGGAGTCCCTTTCTCTCCACTAAGAGCTGAATAAATCGGTGAAAATAAATCAATTGTA TAATAACCATTTCTCTTATATTCTTGGTCTTTGTACCCTCTGCTAGTAATAATATCATTTTCAATTAAAC TATCAAAAGAATTTAATTTATTAACTTCATCCATCGTTAATCTGCGAACAACATTTGTCGCGTATACATT ATTACCGTCTTGATCAAGATCAAATTTATTTTCAATTTTTCTTAGTAACTCATATTTTTGATTTGTTTCT AAATTAGCTACAGCTTTTCCTTCTAAATATTCTAACATATAAATTACATCAAACATATTATGCATATAAT TATGTAGGTCTTCTGCACTATTAAATCGTTGAGTTGGATCAGCTACTTGAAGTCTTGTTGAATTTTCTGA ATCCTCATATTTCAAGACAGAGTTAATTGTTATTGTTGGATCATATGGATGATCCGGAGCTTGTAATAAT CCTTTTGCATAAAACTCAGGTCCTAATCCGCTTCTTCTTCCATATCCTCCAAGATAAATCTCTCTATCTG AGTTATGTGTCATTTCATGAGTATATGTTACAGCTCCATCTTTATCCAACATACGATATGCCATATAATA GAATGCATCTCCGGTAGCATATGCTCCGTGTCCATTATGAACAACATTATTTCCCGCAGGTCCAAAGAAG TATTTTATAGCTGGATGATCAGTTTCAAAAGTAGCTTGATGAGTTACTTTGTCTTTATCTTTGTCAGTAC CAAATTTGAAAGCATCATATACTAGAATACTTCTATATAATTTTTCTTTATTATCGTTATCTAATATCTT ATACCAATAATCATAATGATCTCTAAATCGTTTAGCCGCTTCTTTGGCGTTATCTTCTACAAATTTGTTT AACTTTTCTCCCTTAGGATATTCTGAACTTCTATATCTGTCATAGGCTCCAAATCCAATAGTGGAAATAT TCGCTATCATAAACACTGTTTTTTCTTCAGGTAAAGTTAATAGTGGTAAGACCATACTTTGATATTTCCA AGATGGATTAGTTAATCTATCATATACCCCAATAGAATATTTAGTTCCCTCTTTTCCTTGTTTTTCTCTT CCCTCTTCAATTGTAGATTTTTCTTCTACAATATATGCTTTTGTTTGTTTTTTAAACCACTCATTGTTAG AAATTGTTGGTAAGAATACTTTTCTATATCCTTCTAATGCTTTAAATAAACTTTCAGTTCCATAATTTTT CGCTAATAATACATTATAAGTAATTACATTATTTTTTGCTAATAAATTGTTAAATCCAGATTTACCTAAC TCAATAACATTATCTAATGCAGAACTATTTGATTTACCAAAGAAATCCAAGTGGTACATTATTAAATCTT TAGCATTGGTTTCTCCATAATTAAAATTATACCAGCGTTCTAAATACGTTAATCCTAACAATAAGGCTTC CTTATTATTTTTTATTTTCTCAATTACATAATTATCTATTACCTTATTGTTATTTTCCACTATTGCAGCA TCTGCAGTAAGTAGTTTTGATAAACTGTCTTCTATATTTGCTTTTGTTTTTTCAAATTGTTCACCTAAAT ATAACTCTGTTAATTTTATATTACCAGAAATATCTAATACTTTTCTAACGTCAGCTGAACTATATTGAAC AGATTTCAGATCATTTAAAATAGTTTTTACAATATTATTATAATCATGCAGCATTGTATTAGGTGTATAC ATTAATTTTGTATTAGCTATATCATACTCAGCAACTTTAGAGAAATCATTCTTATATGCAATATTTAATA CTCGTGATTTGTTACCTTCAAAATGTAATAACAATTTGTTTATTTCTTGTTTATTTTTATTAATATCAGT TATTACTTCATTGTTCTTCATAGGAACAACTGATAGAAGTTTTTTAGTAAATAAGTCACTGTTATCCTCT ACTAAATTACCATACTTAACTATTGTTTCTCTGTTATAGAAAGGAAGTAATTTTTCAATATTTTTATATA CTTGTTCTCTCGACTGTTGGTAACCTGTTACTTCATTGTAATTAGTATTGTATCTTGAAGTAAAATCAAA ATCTTCTACTTTAGTGCTGTGTTTAGAAACCAATTCTACCTTTTTCTCTTTTACTTTATCAGCATCTAAT ACCGTACCTCTTTGTACATCTGAATCTTTAGTCACAACCTCATCATCTTCTTGTACTACGTTTACTACCT TATTATTTTTATTGCTATATGTTTCAATCGTTTTTATTCCATTGAAATTATAGCCAGCTATAGCATTACC ATTCGTAACATTGACATCACTTAAAACATATGATAGTTTACCTGATTTACTTACATCTTGTGAATCTCTA TCCCAAAGATTACCTGCAACTCCCCCAACTTTACCAAAGTGTCGCACATTGTTAACATTTCCTTCAACAT AGCTATACTTAATTGTCGCACTTTTCTCAACAACTCCGGCTATACCACCAACAATTTGATCTCCTGATTT TGCATTAGAGGCTATGTCAATCGATGCTATTGATTTCTCTATAGAAGCAAGCGAACCAGAAAGTTTACCT ACTAAACCACCAATTTCATACCCTGCAGTTGTATCATATGTGTTAGTTATTCTGCCTGTAAAACTACTAT TAGAAATTCTCGAGTTATCTACTTTTGAAACCAATCCACCAATTCCACGTTCACCAGCTATAATACCATC AGAATGAACATTATCTATAAGAGTATTGTATTTTGCTTCTTTCGATATTGTAGCAGCATCTTCTTTAGAA GAAACATTCGCTTCTTTTATTGAAAGATTCTGAATAGTAGCGGTGTTTAGAGTTTTAAATAAAGGTTTTT TCAAGTTATAAATAGCATAATACTTACCATTATTTTCACCTATTAATTTTCCGTAAAATTCATTTTTTAC ATAACTTTCTTGATCATCCGGAAGTTCAACTTCACGAGCATCCATAGTTGCACCTAAATGGAATGTTCCA TTAGGGTCACTATTCATTGCATCAACTAAATTTTTAAATGATGTATAGACGCCAGTTTCACTTTGCTGAG TTTTTGGTAAATAATATGTATAGTCATTCGAAATAACATTGTTTTCGTGTTGAATTAGATTTTCTGCATG AGCCACAATTTTGTATACTTCTTTATTGTTTTTTGTTGTACTTTCAATTTTAGTAACAGGCAACATTATA TCTTTAAAATTTTCTGATTTTACCTTCATGAAATACTTCAATGAACTATCTAAAGCACCATCTACAGCCG TAATATGTCGATATTTATTATTTTCTACCGTATATAATTCCACGTTTGAAACATTTCTAAGTTCTAGTTT CTTGTCGACTTGTTTTTCTTCTTTAATTTTATCTTTAGGACGTTCCGATTCCCCATTTGTAGAGCTTGCC TCATTTTCAGGTTTAGTATCTTCTGCACTAGGTTGTTCGATTTTACCAGTATATTCTTTCGGTGCTTCTA CTTTCTCTGGCTCGACTATCGATCCGGCTTGTACCCCTGTGTATTCTGGTAGTGGTGCTACCTGCTCTGG TTCAACAATAGCGCTGGCTTGTGGTCCTGTATATTCTGGAAGCGGTGCTACCTGTTTAGGTTCACCTTTA TCACTTACCACAGTATCTGGCGACTCTGGTTGAACCTCAGTCTCACCTTTGTCAGTCACAACCGCTTCCG GTAGCTCTGGTTGGACTGCTGGTTCACCTTTATCACTTACTACTGCTTCCGGTAGCTCTGGTTGGACAGC GGGCTCACCTTTGTCGGTTACGACTGCTTCCGATAGCTCTGGTTGGACAGCGGGCTCACCTTTGTCGGTT ACGACTGCTTCCGATAGCTCTGGTTGGACAGCGGGCTCACCTTTGTCGGTTACGACTGCTTCCGATAACG CTGGTTGAACTTCTGGTACGCCTTTATCACTTACTACTGCTTCGGGCAACTCAGGCTGAATTGCGGGTTC AACAATAGCTCCAGACTGTACGTCCTTATGTTCTACACCAGTCTCAGGTTGTTCCTTTATAACTTGAGTT TTTTTAGTACCTTTTTCGACTATTCTTGGACTAGGCGCAGTCGTTGAAGTTGAAACAATTTCTCGCGAAA CTTCTTCCTTGTTTACAGAGAATATTCTGACGATTTCAACTTTCTTACCTAATTTACCTTCTTGTTTTAC TCTTACAGTTCCTTCAGCTAAATCAGGATTTTCTTGAGTTTCTTCTTGAAAATCTATTTTTGTCTCTATA GTTTCCTCACGATATAAGAGTTCAGGTTTGTTCAATTGACCTGATAAAACTTCATCCTGTGGATTTAATG TATTTACCCCAGTCTTTTCTTTTGGAGAAATCTTCTCCTCTTTCTTCGTTTCTAGATTCTTATGTTCGGC TAATTGTTCTTGAGAATCTGAAGATTGTTTCTCTTCTTTTCTTGGATTGATTAATTTAGTAGAGAAAGGT TTTTCAACTACTTGAACTTCTGTCGGCTTAGTTGAAGAAACAGGTGTTTGTTCCTGAATAGCTTGTACTG TTGATGGATGGTCTACAAAATTTGGTGTAACATTATAATCCACCTTTTGTTGTTTTGTAGGAGTGGCTGC TGATTTTTCTTGATTACTTACTTCAAAATCAGAAGTCGTTTTTCCCTCTTTGATATATCCAATATAAGTG TAACCTGAAATCTCTTTAGGAAGAGGTAATTTTTCTCCAGAGGTCAATTCATAGTCCGTATTGTAATTTA GCAAAAGATGATTTTCTAAAGCATGGACTGAAACTAAGACACCATTTCCTATTCCTGCAACCAATACTAA ATGTAATACCGTTTTATTCTTAACCTTTTTCTTGGAAACAGCAAAAATTAAAATTCCCAGAGCAGCTAAG CTAGCACCAGCAACTAGGGCTTGCCTCTCATTCTTGCTTCCAGTATTTGGTAATTCCGCCAGTTGATTTT GAGAATTTAACTTATAAACAAGATAATAAGTTTCATCATCATTCTCCACGTATGTCGGAATATCATAGAC AAGCTGCTTCTTTTCTTCTGATGATAGCTCTGAATCTGCCACATATTTATAGTGAACTCCCGCAGTTTCT TGAGCATCCACAGATGAACTAGCTAATACAGACATAAAAAATAAACTTGAAATCGTTGCAGATACAAGTC CTACTGATAATTTTCTAAATGAAAAACGCTCTTGTTTTTCACCAAAATACTTTTCCA
Protein Sequence	>gi\|182684113\|ref\|YP_001835860.1\| immunoglobulin A1 protease [Streptococcus pneumoniae CGSP14] MEKYFGEKQERFSFRKLSVGLVSATISSLFFMSVLASSSVDAQETAGVHYKYVADSELSSEEKKQLVYDIPTYVENDDETYYLVYKLNSQNQLAELPNTGSKNERQALVAGASLAALGILIFAVSKKKVKNKTVLHLVLVAGIGNGVLVSVHALENHLLLNYNTDYELTSGEKLPLPKEISGYTYIGYIKEGKTTSDFEVSNQEKSAATPTKQQKVDYNVTPNFVDHPSTVQAIQEQTPVSSTKPTEVQVVEKPFSTKLINPRKEEKQSSDSQEQLAEHKNLETKKEEKISPKEKTGVNTLNPQDEVLSGQLNKPELLYREETIETKIDFQEETQENPDLAEGTVRVKQEGKLGKKVEIVRIFSVNKEEVSREIVSTSTTAPSPRIVEKGTKKTQVIKEQPETGVEHKDVQSGAIVEPAIQPELPEAVVSDKGVPEVQPALSEAVVTDKGEPAVQPELSEAVVTDKGEPAVQPELSEAVVTDKGEPAVQPELPEAVVSDKGEPAVQPELPEAVVTDKGETEVQPESPDTVVSDKGEPKQVAPLPEYTGPQASAIVEPEQVAPLPEYTGVQAGSIVEPEKVEAPKEYTGKIEQPSAEDTKPENEASSTNGESERPKDKIKEEKQVDKKLELRNVSNVELYTVENNKYRHITAVDGALDSSLKYFMKVKSENFKDIMLPVTKIESTTKNNKEVYKIVAHAENLIQHENNVISNDYTYYLPKTQQSETGVYTSFKNLVDAMNSDPNGTFHLGATMDAREVELPDDQESYVKNEFYGKLIGENNGKYYAIYNLKKPLFKTLNTATIQNLSIKEANVSSKEDAATISKEAKYNTLIDNVHSDGIIAGERGIGGLVSKVDNSRISNSSFTGRITNTYDTTAGYEIGGLVGKLSGSLASIEKSIASIDIASNAKSGDQIVGGIAGVVEKSATIKYSYVEGNVNNVRHFGKVGGVAGNLWDRDSQDVSKSGKLSYVLSDVNVTNGNAIAGYNFNGIKTIETYSNKNNKVVNVVQEDDEVVTKDSDVQRGTVLDADKVKEKKVELVSKHSTKVEDFDFTSRYNTNYNEVTGYQQSREQVYKNIEKLLPFYNRETIVKYGNLVEDNSDLFTKKLLSVVPMKNNEVITDINKNKQEINKLLLHFEGNKSRVLNIAYKNDFSKVAEYDIANTKLMYTPNTMLHDYNNIVKTILNDLKSVQYSSADVRKVLDISGNIKLTELYLGEQFEKTKANIEDSLSKLLTADAAIVENNNKVIDNYVIEKIKNNKEALLLGLTYLERWYNFNYGETNAKDLIMYHLDFFGKSNSSALDNVIELGKSGFNNLLAKNNVITYNVLLAKNYGTESLFKALEGYRKVFLPTISNNEWFKKQTKAYIVEEKSTIEEGREKQGKEGTKYSIGVYDRLTNPSWKYQSMVLPLLTLPEEKTVFMIANISTIGFGAYDRYRSSEYPKGEKLNKFVEDNAKEAAKRFRDHYDYWYKILDNDNKEKLYRSILVYDAFKFGTDKDKDKVTHQATFETDHPAIKYFFGPAGNNVVHNGHGAYATGDAFYYMAYRMLDKDGAVTYTHEMTHNSDREIYLGGYGRRSGLGPEFYAKGLLQAPDHPYDPTITINSVLKYEDSENSTRLQVADPTQRFNSAEDLHNYMHNMFDVIYMLEYLEGKAVANLETNQKYELLRKIENKFDLDQDGNNVYATNVVRRLTMDEVNKLNSFDSLIENDIITSRGYKDQEYKRNGYYTIDLFSPIYSALSGEKGTPGDLMGRRIAFELLAAKGYKEGMVPYISNQYEKDAKAAGSKINSYGKEVGLVTDELVLEKVFNGQYKTWTQFKKDMYKEREKQFSKLNRVNFINPNNPLSRQRNVSVTDIGVLERMIVEAVRDDAQDDVAKFYPETNSRVLKLKKAIYKAYLDQTNDFRSSIFENKK
Molecule Role	Virulence factor
Molecule Role Annotation	MUTATION: iga mutant is attenuated in mice (Chiavolini et al., 2003).
COG	COG3583S, under S: Function unknown
References	*Chiavolini et al., 2003:* Chiavolini D, Memmi G, Maggi T, Iannelli F, Pozzi G, Oggioni MR. The three extra-cellular zinc metalloproteinases of Streptococcus pneumoniae have a different impact on virulence in mice. BMC microbiology. 2003; 3; 14. [PubMed: 12841855].


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iga from Streptococcus pneumoniae CGSP14