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ilvI from Neisseria meningitidis MC58

Victor ID 3026
Gene Name ilvI from Neisseria meningitidis MC58
Sequence Strain (Species/Organism) Neisseria meningitidis MC58
NCBI Gene ID 904184
NCBI Protein GI 15677427
Locus Tag NMB1577
Protein Accession NP_274583.1
Other Database IDs UniProtKB-ID: Q9JYI0_NEIMB
UniRef100: UniRef100_Q9JYI0
UniRef90: UniRef90_B4RJ12
UniRef50: UniRef50_Q89AP7
UniParc: UPI00000C473E
EMBL: AE002098
EMBL-CDS: AAF41930.1
RefSeq_NT: NC_003112.2
HSSP: P07342
EnsemblGenome: EBNEIG00000009476.
EnsemblGenome_TRS: EBNEIT00000009476
EnsemblGenome_PRO: EBNEIP00000009096
GenomeReviews: AE002098_GR
KEGG: nme:NMB1577
NMPDR: fig|122586.1.peg.1517
TIGR: NMB1577
HOGENOM: HBG323037
OMA: ANLAMQN
ProtClustDB: CLSK878135
BioCyc: NMEN122586:NMB_1577-MONOMER
Taxonomy ID 122586
Gene Starting Position 1637874
Gene Ending Position 1639601
Gene Strand (Orientation) -
Protein Name acetolactate synthase III, large subunit
DNA Sequence 
>gi|77358697:1637874-1639601 Neisseria meningitidis MC58, complete genome
CTTACGCCTTTCCGTCCGCACGCATATGCGGCGGAAGTACCATTTCGTCCAAACCTTTGCCGTTGCCGAC
CATGGGCATCACATTCTGTTTCTGGTCGGTCAGGAAGTCGATAAACACCAGCCTGTCTTTTTGGTTCAAT
GCTTCCAACAACGCACCTTCCACATCAGACTTCTTGTCCACGCGGATACCGATATGGCCGTATGCCTCGG
CAAGTTTGACGAAATCGGGCAAAGAATCGAAATAGGTTTCCGACTCTCGTCCGCCGTAATATATTTCCTG
CCACTGGCGTACCATACCGAGATAACCGTTGTTCAGCGTAATGACGTTAACCGGAATCCGATATTGGAAA
CAGGTGGACAGCTCTTGGATGTTCATCTGGATCGAGCCGTCGCCGGTGATACAGAATACGTCTTGATCCG
GGGCGGCAAGTTTTGCACCAATCGCATAAGGCAGACCCACGCCCATCGTACCCAAACCGCCGGAATTGAG
CCATTGGCGCGGACGTTCGAAGGGATAATATTGAGCCGCAAACATTTGATGCTGCCCTACATCCGATGTG
ATGATTGCCGAATTGCCGGTAATCTCGGCAAGCTTCTGAATCACATATTGTGGCTTGATAATTTCGCTGC
CGTTGTCAAACCACAAGCAATCTCGGGAACGCCATTCCTCTATGGTTTTCCACCATTTGCCCAAAGCATC
TTCAGACGGCACGGACTCTTGTTTTTGCCACAGCGCAACCATCTCGGACAAAACGTTTTTCACGTCGCCG
ACAATCGGAATGTCCACCTTCACGCGTTTGGCGATGCTGGAAGGATCGACATCGATATGGATAACCTTCT
TCGCCTTCTCGAAAAATTTGGACGGTACGGAAACCACACGGTCGTCAAAACGCGCACCTACGGCAAGAAC
GACATCCGCATTCTGCATGGCAAGGTTTGCCTCGTAAGTACCGTGCATACCGAGCATACCGAGGAATTGG
CGGTCGCCGGAAGGATAAGCGCCCAAGCCCATCAGCGTACCCGTGCACGGAGCACCCGTCATTCGGACAA
ATCGGGTCAGCTCTTCAGAAGCATTACCCAACACCACGCCGCCGCCAAAATAGACGACCGGACGTTTGGC
AGATGCCAACATCTGCACGGCCTTTTTAATCTGACCGATATGTCCTTGAACAACCGGTTGATACGAACGG
ATAAAAATGTCTTCCTGAGGATAGCTGAATTTCGCCATCGCCTGCGTAACATCTTTCGGGACATCAACCA
CCACGGGCCCCGGTCGGCCGCTTGCGGCAATTTGGAACGCCTTTTTAATGGTTTCCGCCAACTCATTGAT
GTCCGTAACCAGGAAATTGTGTTTGACGCACGGACGGGTAATACCCACCGTATCAACTTCTTGGAACGCA
TCCGTACCAATCAGGGAATTGCCTACCTGCCCGCTGATGACCACCATCGGAATCGAATCCGTATAGGCAG
TAGCAATACCGGTCAGTGCATTGGTAACGCCCGGGCCGGATGTAACCAATGCCACGCCCACCTTACCGCT
GACGCGCGCATACGCATCTGCCGCGTGTACTGCCGCCTGCTCATGGCGGGTAAGAATGTGTTTGAATTTA
TTGAGTTGGAAAAGGGCATCGTAGATTTCGATAACCGCACCGCCGGGATAACCGAAAACGTACTCGACAC
CTTCGGCTTTGAGACTCTGCACTATGATTTGCGCGCCTGATAACTGCA
Protein Sequence 
>gi|15677427|ref|NP_274583.1| acetolactate synthase isozyme III large subunit [Neisseria meningitidis MC58] MQLSGAQIIVQSLKAEGVEYVFGYPGGAVIEIYDALFQLNKFKHILTRHEQAAVHAADAYARVSGKVGVALVTSGPGVTNALTGIATAYTDSIPMVVISGQVGNSLIGTDAFQEVDTVGITRPCVKHNFLVTDINELAETIKKAFQIAASGRPGPVVVDVPKDVTQAMAKFSYPQEDIFIRSYQPVVQGHIGQIKKAVQMLASAKRPVVYFGGGVVLGNASEELTRFVRMTGAPCTGTLMGLGAYPSGDRQFLGMLGMHGTYEANLAMQNADVVLAVGARFDDRVVSVPSKFFEKAKKVIHIDVDPSSIAKRVKVDIPIVGDVKNVLSEMVALWQKQESVPSEDALGKWWKTIEEWRSRDCLWFDNGSEIIKPQYVIQKLAEITGNSAIITSDVGQHQMFAAQYYPFERPRQWLNSGGLGTMGVGLPYAIGAKLAAPDQDVFCITGDGSIQMNIQELSTCFQYRIPVNVITLNNGYLGMVRQWQEIYYGGRESETYFDSLPDFVKLAEAYGHIGIRVDKKSDVEGALLEALNQKDRLVFIDFLTDQKQNVMPMVGNGKGLDEMVLPPHMRADGKA
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: ilvI mutant is attenuated in rats (Sun et al., 2000).
COG COG0028EH, under E: Amino acid transport and metabolism; H: Coenzyme transport and metabolism
References
Sun et al., 2000: Sun YH, Bakshi S, Chalmers R, Tang CM. Functional genomics of Neisseria meningitidis pathogenesis. Nature medicine. 2000; 6(11); 1269-1273. [PubMed: 11062540].