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hmbR from Neisseria meningitidis MC58

Victor ID 3016
Gene Name hmbR from Neisseria meningitidis MC58
Sequence Strain (Species/Organism) Neisseria meningitidis MC58
NCBI Gene ID 903442
NCBI Protein GI 15677517
Locus Tag NMB1668
Protein Accession NP_274673.1
Other Database IDs UniProtKB-ID: Q9JYA8_NEIMB
UniRef100: UniRef100_Q9JYA8
UniRef90: UniRef90_C6M1Y1
UniRef50: UniRef50_C6S8B4
UniParc: UPI00000C4777
EMBL: AE002098
EMBL-CDS: AAF42017.1
RefSeq_NT: NC_003112.2
EnsemblGenome: EBNEIG00000009575.
EnsemblGenome_TRS: EBNEIT00000009575
EnsemblGenome_PRO: EBNEIP00000009195
GenomeReviews: AE002098_GR
KEGG: nme:NMB1668
NMPDR: fig|122586.1.peg.1607
TIGR: NMB1668
HOGENOM: HBG145461
OMA: INDNHRI
ProtClustDB: CLSK870229
BioCyc: NMEN122586:NMB_1668-MONOMER
Taxonomy ID 122586
Gene Starting Position 1740258
Gene Ending Position 1742633
Gene Strand (Orientation) -
Protein Name hemoglobin receptor
DNA Sequence 
>gi|77358697:1740258-1742633 Neisseria meningitidis MC58, complete genome
ATTAAAACTTCCATTCCAGCGATACGGCGTAATTGCGGCCTGGGGCGCGGTAGCGGTCTAAGCCTTTGCC
ATCGCGGTCGACCGCATTGGTGGTGCTGTAGCTATATAAACCGCGCAGGGAATCCCAAGTGGTGTATTTG
CGGTTGAACAGGTTGTACACGCCTGCACGCAAAGTCAGGTTTTTAGCCGGTTTGTAGAAGCCGTACATAT
CAAACACATAAGCCGACTTGTTCAGCCACGGGTAATCTTTTACCTTTTTCTGCAAAGGCGTACCCCAGCC
CTTGTTTTCATAAACGGTGTATTGCGCGTCTTTGACCTTTTTCGCGCCTAGATAGGTCAGGCGGGAGAAT
ACGCCCCATTTTTCGCTCGGACTTTCATAGTCGATACCGGCAATCACTTTCAGCGGCTGTGTGGACAGCA
GGCTGTTGTCGCCCGACAGTTTGCTTTTCGCATAACCCAGCGAGCCGAACAGTTTCCAACCCTCAGGAAC
AAAAGACGCTACTTTGTCCACATTCAGACGGCCTGTCAGCTCGATACCGCGGATTCTGGCCTTGTCGATA
TTTTTCATCTGCCAATCCAGTTTTTCTTTGTAGGGGTCGCTGCATATACCGTAGTAAGCATTTTCCTCAG
TACAGCCGGGAGTGCCGCTGGTGGTCAGCTTCTGCTCTTCAGACAGGAAATTGCGGTAATTGCTTTGATA
CAGGTTGGCATCCAGCATGCCTTTTTCGCTGCGGCCTTGCAGAGACAGGGTGTGGGTGGTGCTGCGCTCG
GCTTTCAGGTTGGGATTGGGCAGCCAATTACCCGAACCGTGGTTGTAAGTGAAATACACTTCGGACGCAT
TGGGGACACGGTAGCCGGAAGTAATGTCGTAACCGACACGCCAAGCCTGATTCAGTTGCGCCGCCAAGCC
GACAAAACCGCTCCAGCCTTTATAAGTGTTGGCTGCAGGTGGTGTTTTGTCACAAGCATGACACTCGGCA
TTCAATTCCTGAGGCGTCATTTTGGTGTGGTCGTAACGGATACCTGCGCGGCTACTGAACACGTCGTTCC
ATTGAATTTGGTCAGACAGTGAGAAACCGTAGTTGGTGGTTTTCACCGGATGCTGGATACTGCTGGTGGT
TCGAACAACACGGCCGCTGAAGTAATAATCGTCGCGGTTTAGGTTTTCAAAATCACGGCGGCTGACGAAA
GTTTTAAACGACAGGCGGTGTCGCCCCCCCCCGAGTTGCAACGGATGGCTGTCCAAACGCAAAGTAAAAC
GTTTGAATCGGGTGTCCATGCTGCGGTTGTATATTTCGTCCAAATCCTTCTGATTATAGTTGCGCGTCCA
GGTGGAATAATCCATCGGGAACGAGCCTTTGTTGTTAACCGCCGCCACTTTGGTTTTCTGATAATCGAAG
TCCGCCTTCAAAGACGACAACCAATTTGAATCAGGCATCCATTCGTAAAAGAGGTTGGCATTGCGCCGTC
TGTTTACGTCATCGGCTTCGCGCCAGGAAGAAGCGGTCAGGTTATAAGACTCTTCAACCGTGTAATTATG
TCCCTGCTGGCCGTTAAGCGATGCGCCGATGCGGTGGTTATCGTTAATTTGGTAAGCAATCTTACCCAAA
AAGCTGTGGTATTTGTGTTTGGACGAATCAGGGATACCGCGTGCCGAACCACGGATATTCGCGCCACTGC
CTTCCCCTTCCACAGCATAGCCTCGGTTTCCCGCACTTTCGGTTTCATGACCGCGACGTTGCGAATACAG
CAAAGCAGCATCCACGCGGTCGTTACTCACACCGAAACCGAGAGTATTTGTCCATTCACGGTTACGCGTG
CTGTAACCGTTTTTCATCATCACGCCGAATTGCCTGTCGTCCAACAGCAAATCACGGCCTTGCAGCGTTT
GGTAATTCACACCGCCGCCCAATGCACCACTGCCGGTATTGAAAGAGTCTGCGCCCTTCACGATTTCGAT
GTTGCGCACGAGTTCGGGGTCGATAGACAAACGCGAGCTGTTGAAGTTGCCATAACGGGCGTACAGCGAG
TTTTCTTCAGAATCAGGCAGGTTTACACCGTCTATGCTCACGCCGACACGGTTGCCTTCCACGCCGCGAA
CAGCAAAGCCTTTTTGATGGCGGCCGCTGTCGCTCAAGCCGACATCGGTGGAATAGCGCACCAAGTCTTT
ATTGTCGCGTATCATTTCTTGTTTGATACGGTTAAGGTTGACGCGTTCCACAGCCGCAGGCGCATTGCGC
TGACCTTTAACGCGCACTGCTTTTATCTCTGCCTTAACGGGTGTGGTTTCAGTTGCAGCTTCATCTGCTG
CCAAGACCGGATTGCCGAAAATACTGCCGACCAGCGCGGCGATAGGGAGCATTTGTAATGGTTTCA
Protein Sequence 
>gi|15677517|ref|NP_274673.1| hemoglobin receptor [Neisseria meningitidis MC58] MKPLQMLPIAALVGSIFGNPVLAADEAATETTPVKAEIKAVRVKGQRNAPAAVERVNLNRIKQEMIRDNKDLVRYSTDVGLSDSGRHQKGFAVRGVEGNRVGVSIDGVNLPDSEENSLYARYGNFNSSRLSIDPELVRNIEIVKGADSFNTGSGALGGGVNYQTLQGRDLLLDDRQFGVMMKNGYSTRNREWTNTLGFGVSNDRVDAALLYSQRRGHETESAGNRGYAVEGEGSGANIRGSARGIPDSSKHKYHSFLGKIAYQINDNHRIGASLNGQQGHNYTVEESYNLTASSWREADDVNRRRNANLFYEWMPDSNWLSSLKADFDYQKTKVAAVNNKGSFPMDYSTWTRNYNQKDLDEIYNRSMDTRFKRFTLRLDSHPLQLGGGRHRLSFKTFVSRRDFENLNRDDYYFSGRVVRTTSSIQHPVKTTNYGFSLSDQIQWNDVFSSRAGIRYDHTKMTPQELNAECHACDKTPPAANTYKGWSGFVGLAAQLNQAWRVGYDITSGYRVPNASEVYFTYNHGSGNWLPNPNLKAERSTTHTLSLQGRSEKGMLDANLYQSNYRNFLSEEQKLTTSGTPGCTEENAYYGICSDPYKEKLDWQMKNIDKARIRGIELTGRLNVDKVASFVPEGWKLFGSLGYAKSKLSGDNSLLSTQPLKVIAGIDYESPSEKWGVFSRLTYLGAKKVKDAQYTVYENKGWGTPLQKKVKDYPWLNKSAYVFDMYGFYKPAKNLTLRAGVYNLFNRKYTTWDSLRGLYSYSTTNAVDRDGKGLDRYRAPGRNYAVSLEWKF
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: hmbR mutant was attenuated in an infant rat model (Stojiljkovic et al., 1995).
COG COG1629P, under P: Inorganic ion transport and metabolism
References
Stojiljkovic et al., 1995: Stojiljkovic I, Hwa V, de Saint Martin L, O'Gaora P, Nassif X, Heffron F, So M. The Neisseria meningitidis haemoglobin receptor: its role in iron utilization and virulence. Molecular microbiology. 1995; 15(3); 531-541. [PubMed: 7783623].