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tonB from Neisseria meningitidis MC58

Victor ID 3009
Gene Name tonB from Neisseria meningitidis MC58
Sequence Strain (Species/Organism) Neisseria meningitidis MC58
NCBI Gene ID 903369
NCBI Protein GI 15677576
Locus Tag NMB1730
Protein Accession NP_274733.1
Other Database IDs UniProtKB-ID: TONB_NEIMB
UniRef100: UniRef100_P57004
UniRef90: UniRef90_O06432
UniRef50: UniRef50_O06432
UniParc: UPI00000510AC
EMBL: AE002098
EMBL-CDS: AAF42075.1
RefSeq_NT: NC_003112.2
EnsemblGenome: EBNEIG00000010739
EnsemblGenome_TRS: EBNEIT00000010739
EnsemblGenome_PRO: EBNEIP00000010359
GenomeReviews: AE002098_GR
KEGG: nme:NMB1730
NMPDR: fig|122586.1.peg.1667
TIGR: NMB1730
HOGENOM: HBG134785
OMA: NEINAYK
ProtClustDB: CLSK878208
BioCyc: NMEN122586:NMB_1730-MONOMER
Taxonomy ID 122586
Gene Starting Position 1812856
Gene Ending Position 1813698
Gene Strand (Orientation) -
Protein Name TonB protein
DNA Sequence 
>gi|77358697:1812856-1813698 Neisseria meningitidis MC58, complete genome
CCTAATTCAATTCAAACTTGACGGGGACTTTAAACTCCGTCCAGGCATTGGCTTGAAAATGCCCGTTTTG
CGCCGCCTTGCGTGCCGCATTGTCCAACCGGGAAAAACCACTGCTTTTCACGATTTTAACGGACTCAACA
TGACCGCCCGGAGAAACCAAAACGCTCAAAACAACCGTACCCTGCTCGTCATTCTCCATAGAAAGCGTGG
GATAAGCCGGGCGCGGAATGCTGCCGTTGGCGCGTAAAGGATTGCCTTTGCTGCTGCCGGCTCCTTCCCC
GTGTTCGCCTTTGACACCGCCGCTACCTTTACCGCTGCCTTCTCCGCGCCCCGTTCCGTCTCCTTTGGTA
CCAGTTCCCTTATCTTCCCCATTGCCCTGCTCGCTGTCTGCTTTGGCAGAAGCATTGCCGGGATGTTCGG
CAGGTTTTTCAGACGGCTTCTCGACCGGTTTTTCCGCCGGTTTCGGGACAGGCTTCGCTTCCGGCTTAGG
CTCTGGTTTCGGTTTTTCTTCGGGTTTCGGCTTTTCTTCAGGTTTCGGCTCTTCCTTAGGCTGCTGAATA
TCCGCATCCGCCTTTTTCGTAACCACCGGCTTCAAAACCGGCTTGGGCGGCTCGACAGGTTTGGGCGGCT
CGGGCACGGGTTGCGGTTCGGGCGCAGCAGGCGCGCCTGCACCTTCGGGGGCGCCGTCCCCTCCGCCAAA
ATCGCCCAAATCGACAAATTCAATAACATTGCCTGACTCTATCACGGGCAGCTTGTGCGCCTGCCAGAGC
AATGCCACCATTGCCAAATGCAGCAGTGCGACGGAAAACACGACTGCGGGGGTTAAAATTCGTTCTTTAT
CCA
Protein Sequence 
>gi|15677576|ref|NP_274733.1| TonB protein [Neisseria meningitidis MC58] MDKERILTPAVVFSVALLHLAMVALLWQAHKLPVIESGNVIEFVDLGDFGGGDGAPEGAGAPAAPEPQPVPEPPKPVEPPKPVLKPVVTKKADADIQQPKEEPKPEEKPKPEEKPKPEPKPEAKPVPKPAEKPVEKPSEKPAEHPGNASAKADSEQGNGEDKGTGTKGDGTGRGEGSGKGSGGVKGEHGEGAGSSKGNPLRANGSIPRPAYPTLSMENDEQGTVVLSVLVSPGGHVESVKIVKSSGFSRLDNAARKAAQNGHFQANAWTEFKVPVKFELN
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: tonB mutant is unable to replicate within human epithelial cells (Larson et al., 2002).
COG COG0810M, under M: Cell wall/membrane/envelope biogenesis
References
Larson et al., 2002: Larson JA, Higashi DL, Stojiljkovic I, So M. Replication of Neisseria meningitidis within epithelial cells requires TonB-dependent acquisition of host cell iron. Infection and immunity. 2002; 70(3); 1461-1467. [PubMed: 11854233].