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aroB from Neisseria meningitidis MC58

Victor ID 3007
Gene Name aroB from Neisseria meningitidis MC58
Sequence Strain (Species/Organism) Neisseria meningitidis MC58
NCBI Gene ID 903286
NCBI Protein GI 15677650
Locus Tag NMB1814
Protein Accession NP_274811.1
Other Database IDs UniProtKB-ID: AROB_NEIMB
UniRef100: UniRef100_A1KS84
UniRef90: UniRef90_Q5FAD4
UniRef50: UniRef50_A5CX62
UniParc: UPI0000125F76
EMBL: AE002098
EMBL-CDS: AAF42149.1
RefSeq_NT: NC_003112.2
EnsemblGenome: EBNEIG00000009123
EnsemblGenome_TRS: EBNEIT00000009123
EnsemblGenome_PRO: EBNEIP00000008743
GenomeReviews: AE002098_GR
KEGG: nme:NMB1814
TIGR: NMB1814
HOGENOM: HBG632303
OMA: CEIKAEV
ProtClustDB: PRK00002
BioCyc: NMEN122586:NMB_1814-MONOMER
Taxonomy ID 122586
Gene Starting Position 1905445
Gene Ending Position 1906524
Gene Strand (Orientation) +
Protein Name 3-dehydroquinate synthase
DNA Sequence 
>gi|77358697:1905445-1906524 Neisseria meningitidis MC58, complete genome
AATGAAAACACTGACCGTACACACCCCGTCCCACAGCTACCCCATCTTTATCGGCAACGGACTGCTGCCG
CAGGCAGGAAGCCTGCTCAAACCGCATTTGGGCAAACGCGCCGCCATCATCGCCAACGAAACCGTCGCCC
CGCTCTACCTCGGCACGCTTCAGACGGCATTGGATGCGGCAGGCGTATCCCATTTCAGCATCATCCTGCC
CGACGGCGAGGCGCACAAAAACTGGCAGACGCTCAACCTCATCTTTGACGGGCTGATGCAAAACCGCGCC
GAACGCAAAACCACATTAATCGCACTGGGCGGCGGCGTGATCGGCGACATGGTCGGCTTTGCCGCTGCCA
CCTACCAGCGCGGCGCACCGTTCGTTCAAATACCGACCACGCTGTTGAGTCAGGTCGACTCATCGGTGGG
CGGCAAAACCGCCATCAACCACCCGCTCGGCAAAAATATGATTGGCGCGTTTTACCAGCCGCAGGCGGTG
CTTGCCGACTTGGACACGCTGCACACCCTGCCCGCCCGCGAATTGTCCGCCGGTATGGCGGAAGTCATCA
AATACGGCGCGCTCGGCGACATCGGCTTTTTTGAATGGCTGGAACAGCATATGCCCGAACTGATGACGCT
CGATCGGGAAAAACTCGCCCAAGCCGTGTACCGCTGCTGCCAAATGAAGGCAGACATCGTCGCCCAAGAC
GAAACCGAACAGGGCATACGCGCATGGCTCAACCTCGGACACACCTTCGGACACGCCATTGAAACCGAGA
TGGGTTACGGCACTTGGCTGCATGGAGAAGCCATCGCCGCCGGCTGCGTGTTGGCGGCGCGTTTGTCCGA
ACAACTGGGCAAAACCTCCGCCGCAGATACCGCGCGGCTCGCCGCCCTGCTCGAAGCCGCCGGACTGCCG
TCCGCGCCACCCGTGTTTGCCTTTGAAAAATGGCTGGAACACATGAGCCACGATAAAAAAGTCAGCGGCG
GCATCATGCGCTTTATCGGTCTGAACCGGCTGGGCGAAGCCAACATCACCGAAATTACCGACACGGACAT
CCTCCGCCGCACCCTGCAACCGTATCTCTG
Protein Sequence 
>gi|15677650|ref|NP_274811.1| 3-dehydroquinate synthase [Neisseria meningitidis MC58] MKTLTVHTPSHSYPIFIGNGLLPQAGSLLKPHLGKRAAIIANETVAPLYLGTLQTALDAAGVSHFSIILPDGEAHKNWQTLNLIFDGLMQNRAERKTTLIALGGGVIGDMVGFAAATYQRGAPFVQIPTTLLSQVDSSVGGKTAINHPLGKNMIGAFYQPQAVLADLDTLHTLPARELSAGMAEVIKYGALGDIGFFEWLEQHMPELMTLDREKLAQAVYRCCQMKADIVAQDETEQGIRAWLNLGHTFGHAIETEMGYGTWLHGEAIAAGCVLAARLSEQLGKTSAADTARLAALLEAAGLPSAPPVFAFEKWLEHMSHDKKVSGGIMRFIGLNRLGEANITEITDTDILRRTLQPYL
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: aroB mutant is attenuated in rats (Sun et al., 2000).
COG COG0337E, under E: Amino acid transport and metabolism
References
Sun et al., 2000: Sun YH, Bakshi S, Chalmers R, Tang CM. Functional genomics of Neisseria meningitidis pathogenesis. Nature medicine. 2000; 6(11); 1269-1273. [PubMed: 11062540].