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fhs from Neisseria meningitidis MC58

Victor ID 3005
Gene Name fhs from Neisseria meningitidis MC58
Sequence Strain (Species/Organism) Neisseria meningitidis MC58
NCBI Gene ID 903260
NCBI Protein GI 15677675
Locus Tag NMB1839
Protein Accession NP_274836.1
Other Database IDs UniProtKB-ID: FTHS_NEIMB
UniRef100: UniRef100_Q9JXY2
UniRef90: UniRef90_Q5FAG1
UniRef50: UniRef50_Q2RM91
UniParc: UPI00000C47DE
EMBL: AE002098
EMBL-CDS: AAF42174.1
RefSeq_NT: NC_003112.2
EnsemblGenome: EBNEIG00000010919
EnsemblGenome_TRS: EBNEIT00000010919
EnsemblGenome_PRO: EBNEIP00000010539
GenomeReviews: AE002098_GR
KEGG: nme:NMB1839
NMPDR: fig|122586.1.peg.1770
TIGR: NMB1839
HOGENOM: HBG677721
OMA: KMPGLPK
ProtClustDB: PRK13505
BioCyc: NMEN122586:NMB_1839-MONOMER
Taxonomy ID 122586
Gene Starting Position 1939770
Gene Ending Position 1941446
Gene Strand (Orientation) -
Protein Name formate--tetrahydrofolate ligase
DNA Sequence 
>gi|77358697:1939770-1941446 Neisseria meningitidis MC58, complete genome
TTCAGAACAAGCCGTGAATCACGCCTTCTGCGTCCACATCGATTTTCTCGGCAGCCGGAACTTTGGGCAG
GCCGGGCATTTTCATCATGTTGCCGCACAGGGCGACGATGAAACCTGCGCCTGCGGAAACGGTGATGCCG
CGCACGGCGATGCGGAAGTCTTCGGGGCAGCCCAACAGTTTGGCGTTGTCGCTCAAAGAGTATTGGGTTT
TCGCCATGCAGATCGGCATTTTGTCCAAGCCCAGTTTTTCCAGTGAAGCGATTTCGGCAGACGCTTCCGC
GCTGAAATCAACATCTTCCGCGCCGTACACTTTTTGGGCAATCGCACGGATTTTGTCTTTGATGCCCAAC
TCGACATCGTAGGCGAAACCGAAGTTATTGGTTTGACTTTCAATGGCGTTGACGACTTTGCGCGCCAAAT
CCGCGCCGCCCGCACCACCTTTGCCCCACACTTCGGTCAGGGAAACTTCAACGCCGTGTTCGGCACAGGC
TTTTTCAATCATCGCCAACTCGGCATCGGCGTCGGACACGAAGCGGTTGAGCGCAACGACGACGGGCAGT
CCGAATACGTTTTTCAGGTTGGAAATGTGTTTCAGCAGGTTGGGCAAACCTTTTTCCAAAGCGTCTAAAT
TTTCTTCGCCGAGGTTGGCGCGTTCCACGCCGCCGTTATATTTCAACGCGCGGACAGTCGCCACGACAAC
AGCCGCATCAGGTTTCAAACCGGCAAGGCGGCATTTGATGTCGCAGAATTTTTCCGCGCCCAAGTCCGCG
CCGAAGCCTGCTTCGGTTACGGCGTAATCGGCAAGGTGTTTCGCCAGACGGGTTGCGGTTACGGAGTTGC
AGCCGTGGGCGATGTTGGCGAACGGGCCGCCGTGTACGAAGGCGGGCGTGCCTTCGATGGTTTGCACCAA
GTTGGGCTTAATCGCATCTTTAAGCAATGCCGCCATCGCGCCATTCGCTTTCAAATCTTTGGCGTAAACG
GGGCTGCCGTCTTTGGCGTAGGCGACAAGGATGTTGCCCAAACGCTCTTTCAAATCGCTGATGTCTTTGG
CAAGACAGAATACCGCCATCACTTCGGAAGCAACGGTAATATCGAAACCGTCAGGACGCATCACGCCGTC
AACGGGTTTACCCATGCCGTCGATGATGTTGCGCAACTGGCGGTCGTTCATATCGACCACGCGCCGCCAC
AGCACGCGTTTGGGGTCGATGTTCAACTCGTTGCCTTGGTAGATATGGTTGTCGAGCATCGCGGCAAGCA
GATTATTTGCCGCACCGATGGCGTGAAAATCTCCGGTGAAGTGCAGGTTGATGTCTTCCATCGGCAAAAC
TTGGGCATAGCCGCCGCCTGCCGCGCCGCCTTTCACGCCGAACACCGGCCCCAGAGAAGGTTCGCGCAGG
GCAATCACGGCATCTTTGCCGATGTGGCGCAACGCGTCCGCCAAACCGATGGTTACGGTGGTTTTGCCTT
CGCCCGCCGGAGTCGGGTTGATGGCGGTAACCAAAATCAGCCTGCCCTGTTTTTGCGGCAGTTTGAACGC
TTCGGCAGGATTGATTTTCGCCTTGTAATGACCGTAAGGCTCAATGTTGTCGGCATTCAGACCAAGCTTG
GCGGCAATTTCGCCAATCGGGCGCATGGTGGAGGATTGGGCGATTTCGGCATCGGTTTTGAAGCTCA
Protein Sequence 
>gi|15677675|ref|NP_274836.1| formate--tetrahydrofolate ligase [Neisseria meningitidis MC58] MSFKTDAEIAQSSTMRPIGEIAAKLGLNADNIEPYGHYKAKINPAEAFKLPQKQGRLILVTAINPTPAGEGKTTVTIGLADALRHIGKDAVIALREPSLGPVFGVKGGAAGGGYAQVLPMEDINLHFTGDFHAIGAANNLLAAMLDNHIYQGNELNIDPKRVLWRRVVDMNDRQLRNIIDGMGKPVDGVMRPDGFDITVASEVMAVFCLAKDISDLKERLGNILVAYAKDGSPVYAKDLKANGAMAALLKDAIKPNLVQTIEGTPAFVHGGPFANIAHGCNSVTATRLAKHLADYAVTEAGFGADLGAEKFCDIKCRLAGLKPDAAVVVATVRALKYNGGVERANLGEENLDALEKGLPNLLKHISNLKNVFGLPVVVALNRFVSDADAELAMIEKACAEHGVEVSLTEVWGKGGAGGADLARKVVNAIESQTNNFGFAYDVELGIKDKIRAIAQKVYGAEDVDFSAEASAEIASLEKLGLDKMPICMAKTQYSLSDNAKLLGCPEDFRIAVRGITVSAGAGFIVALCGNMMKMPGLPKVPAAEKIDVDAEGVIHGLF
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: fhs mutant is attenuated in rats (Sun et al., 2000).
COG COG2759F, under F: Nucleotide transport and metabolism
References
Sun et al., 2000: Sun YH, Bakshi S, Chalmers R, Tang CM. Functional genomics of Neisseria meningitidis pathogenesis. Nature medicine. 2000; 6(11); 1269-1273. [PubMed: 11062540].