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opc

Victor ID 3004
Gene Name opc
Sequence Strain (Species/Organism) Neisseria meningitidis MC58
NCBI Gene ID 903235
NCBI Protein GI 15676939
Locus Tag NMB1053
Protein Accession NP_274087.1
Other Database IDs UniProtKB-ID: Q7DDI3_NEIMB
UniRef100: UniRef100_Q51229
UniRef90: UniRef90_A9LYX2
UniRef50: UniRef50_A9LYX2
UniParc: UPI0000004B04
EMBL: AE002098
EMBL-CDS: AAF41451.1
RefSeq_NT: NC_003112.2
HSSP: Q9AE79
EnsemblGenome: EBNEIG00000009929.
EnsemblGenome_TRS: EBNEIT00000009929
EnsemblGenome_PRO: EBNEIP00000009549
GenomeReviews: AE002098_GR
KEGG: nme:NMB1053
NMPDR: fig|122586.1.peg.1021
TIGR: NMB1053
HOGENOM: HBG576572
OMA: EAGPFYK
ProtClustDB: CLSK877876
BioCyc: NMEN122586:NMB_1053-MONOMER
Taxonomy ID 122586
Gene Starting Position 1071408
Gene Ending Position 1072226
Gene Strand (Orientation) -
Protein Name class 5 outer membrane protein
DNA Sequence 
>gi|77358697:1071408-1072226 Neisseria meningitidis MC58, complete genome
ATCAGAATTTTATGCCGACGCGCAAGCCGTATTCACGAATACTGGTTTTCGGGATGGTGAGCGATACGTC
GCCACTCTTGGTTGTTACACTAAACTCGCCGGATTCTTTGTAAGTGCGTTGTTTGTAGAACGGCCCCGCC
TCGATGCTGGCGGATTCGCCCAGTTTTTTACCAATATTTGCACCCAATCCAAAGCCCCAGCCGTTGGTTT
TTTGATTGATGTCTTTTTTGAGATTGGTAACGCCGGTGTTTAATTTATAGCGGGAATTGAGGTCAAATTT
CACTTCAGACCAAGGGTTGATATACCAGCCGTTACCCAGTTGGGAAAGCAAATCCGCGTGAACTTTGGCT
AACCACGACTGACGGCTGCTGTGAAGCGTATGCTTGGTGGTTTTAATGCTGTCTTTTGAAGATTCAAAAC
CCAAGCCGGCACCCACACGGAAATTTAAAGAATCACTTAACGTTTGGGTGTAGGTGTAGCCTGTGTAAAG
ATCGATACGGTTTTCAGGAACGCCGGTGGGCAGTTTTACATTTTTAGTCTTACCCAGCTTGTTCTCATCT
GTTTCCAAATTAATAATATTTTTTTTGCTGCGCCCGAAACCGGCTTCCAAGCGGATGCCTTGGTTGGCAT
CAAAAGGAATATCAGCACGCACGCTGATGTGTTTGGCAGCTTTGTGTTTTTCTTTCAGGAAAGCACGAGT
TGAAGAAATGGAAGAGAGGTCGGTGTGGACGGTAAACTCATTAGCGGTTTGAAGCTCTTGTGCAGCGGCG
GCAGTACCGGTCAGGGCAATCATGGCACATGTAAAAACTGTTTTTTTCA
Protein Sequence 
>gi|15676939|ref|NP_274087.1| class 5 outer membrane protein [Neisseria meningitidis MC58] MKKTVFTCAMIALTGTAAAAQELQTANEFTVHTDLSSISSTRAFLKEKHKAAKHISVRADIPFDANQGIRLEAGFGRSKKNIINLETDENKLGKTKNVKLPTGVPENRIDLYTGYTYTQTLSDSLNFRVGAGLGFESSKDSIKTTKHTLHSSRQSWLAKVHADLLSQLGNGWYINPWSEVKFDLNSRYKLNTGVTNLKKDINQKTNGWGFGLGANIGKKLGESASIEAGPFYKQRTYKESGEFSVTTKSGDVSLTIPKTSIREYGLRVGIKF
Molecule Role Virulence factor
Molecule Role Annotation Bacteria expressing low or undetectable levels of Opc protein failed to adhere to or invade eukaryotic cells (Virji et al., 1992).
References
Virji et al., 1992: Virji M, Makepeace K, Ferguson DJ, Achtman M, Sarkari J, Moxon ER. Expression of the Opc protein correlates with invasion of epithelial and endothelial cells by Neisseria meningitidis. Molecular microbiology. 1992; 6(19); 2785-2795. [PubMed: 1435257].