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pilQ from Neisseria meningitidis MC58

Victor ID 3001
Gene Name pilQ from Neisseria meningitidis MC58
Sequence Strain (Species/Organism) Neisseria meningitidis MC58
NCBI Gene ID 903122
Uniprot ID Q70M91
NCBI Protein GI 15678016
Locus Tag NMB1812
Protein Accession NP_274809.1
Other Database IDs UniProtKB-ID: PILQ_NEIMB
UniRef100: UniRef100_Q70M91
UniRef90: UniRef90_Q70M91
UniRef50: UniRef50_Q5FAD2
UniParc: UPI0000031D9F
EMBL: AJ564200
EMBL: AE002098
EMBL-CDS: CAD91899.1
EMBL-CDS: AAY52170.1
RefSeq_NT: NC_003112.2
EnsemblGenome: EBNEIG00000010767
EnsemblGenome_TRS: EBNEIT00000010767
EnsemblGenome_PRO: EBNEIP00000010387
GenomeReviews: AE002098_GR
KEGG: nme:NMB1812
NMPDR: fig|122586.1.peg.1743
TIGR: NMB1812
HOGENOM: HBG482665
OMA: QNVPWDQ
ProtClustDB: CLSK878435
Taxonomy ID 122586
Gene Starting Position 1901642
Gene Ending Position 1903951
Gene Strand (Orientation) +
Protein Name pilQ protein
DNA Sequence 
>gi|77358697:1901642-1903951 Neisseria meningitidis MC58, complete genome
TATGAATACCAAACTGACAAAAATCATTTCCGGTCTCTTTGTCGCAACCGCCGCCTTTCAGACAGCATCG
GCAGGAAACATTACAGACATCAAAGTTTCCTCCCTGCCCAACAAACAGAAAATCGTCAAAGTCAGCTTTG
ACAAAGAGATTGTCAACCCGACCGGCTTCGTAACCTCCTCACCGGCCCGCATCGCCTTGGACTTTGAACA
AACCGGCATTTCCATGGATCAACAGGTACTCGAATATGCCGATCCTCTGTTGAGCAAAATCAGTGCCGCA
CAAAACAGCAGCCGTGCGCGTCTGGTTCTGAATCTGAACAAACCGGGCCAATACAATACCGAAGTACGCG
GGAACAAAGTTTGGATATTCATTAACGAATCGGACGATACCGTGTCCGCCCCCGCACGCCCCGCCGTAAA
AGCCGCGCCTGCCGCACCGGCAAAACAACAGGCTGCCGCACCGTCTACCAAGTCCGCAGTATCCGTATCC
GAACCCTTTACCCCGGCAAAACAACAGGCTGCCGCACCGTTTACCGAGTCCGTAGTATCCGTATCCGCAC
CGTTCAGCCCGGCAAAACAACAGGCGGCGGCATCAGCAAAACAACAGGCGGCAGCACCAGCAAAACAACA
GGCGGCAGCACCAGCAAAACAACAGGCGGCAGCACCAGCAAAACAAACCAATATCGATTTCCGCAAAGAC
GGCAAAAATGCCGGCATTATCGAATTGGCTGCATTGGGCTTTGCCGGGCAGCCCGACATCAGCCAACAGC
ACGACCACATCATCGTTACGCTGAAAAACCATACCCTGCCGACCACGCTCCAACGCAGTTTGGATGTGGC
AGACTTTAAAACACCGGTTCAAAAGGTTACGCTGAAACGCCTCAATAACGACACCCAGCTGATTATCACA
ACAGCCGGCAACTGGGAACTCGTCAACAAATCCGCCGCGCCCGGATACTTTACCTTCCAAGTCCTGCCGA
AAAAACAAAACCTCGAGTCAGGCGGCGTGAACAATGCGCCCAAAACCTTCACAGGCCGGAAAATCTCCCT
TGACTTCCAAGATGTCGAAATCCGCACCATCCTGCAGATTTTGGCAAAAGAATCCGGAATGAACATTGTT
GCCAGCGACTCCGTCAACGGCAAAATGACCCTCTCCCTCAAGGATGTGCCTTGGGATCAGGCTTTGGATT
TGGTTATGCAGGCGCGCAACCTCGATATGCGCCAGCAAGGGAATATCGTCAACATCGCGCCCCGCGACGA
GCTGCTTGCCAAAGACAAAGCCCTCTTACAGGCAGAAAAAGACATTGCCGATTTGGGTGCGCTGTATTCC
CAAAACTTCCAGTTGAAATACAAAAATGTGGAAGAATTCCGCAGCATCCTGCGTTTGGACAATGCCGACA
CGACCGGAAACCGCAACACGCTTATCAGCGGCAGGGGCAGCGTGCTGATCGATCCCGCCACCAACACCCT
GATTGTTACCGACACCCGCAGCGTCATCGAAAAATTCCGCAAACTGATTGACGAATTGGACGTACCCGCG
CAACAAGTGATGATTGAGGCGCGTATCGTCGAAGCGGCAGACGGCTTCTCGCGCGATTTGGGCGTTAAAT
TCGGCGCGACAGGCAAGAAAAAGCTGAAAAATGATACAAGCGCATTCGGCTGGGGGGTAAACTCCGGCTT
CGGCGGCGACGATAAATGGGGGGCCGAAACCAAAATCAACCTGCCGATTACCGCTGCCGCAAACAGCATT
TCGCTGGTGCGCGCGATTTCCTCCGGTGCCTTGAATTTGGAATTGTCCGCATCCGAATCGCTTTCAAAAA
CCAAAACGCTTGCCAATCCGCGCGTGCTGACCCAAAACCGCAAAGAGGCCAAAATCGAATCCGGTTACGA
AATTCCTTTCACCGTAACCTCAATCGCGAACGGCGGCAGCAGCACGAACACGGAACTCAAAAAAGCCGTC
TTGGGGCTGACCGTTACGCCGAACATCACGCCCGACGGCCAAATCATTATGACCGTCAAAATCAACAAGG
ACTCGCCTGCGCAATGTGCCTCCGGTAATCAGACGATCCTGTGTATTTCGACCAAAAACCTGAATACGCA
GGCTATGGTTGAAAACGGCGGCACATTGATTGTCGGCGGTATTTATGAAGAAGACAACGGCAATACGCTG
ACCAAAGTCCCCCTGTTGGGCGACATCCCCGTTATCGGCAACCTCTTTAAAACACGCGGGAAAAAAACCG
ACCGCCGCGAACTGCTGATTTTCATTACCCCGAGGATTATGGGTACGGCCGGCAACAGCCTGCGCTATTG
Protein Sequence 
>gi|15678016|ref|NP_274809.1| pilQ protein [Neisseria meningitidis MC58] MNTKLTKIISGLFVATAAFQTASAGNITDIKVSSLPNKQKIVKVSFDKEIVNPTGFVTSSPARIALDFEQTGISMDQQVLEYADPLLSKISAAQNSSRARLVLNLNKPGQYNTEVRGNKVWIFINESDDTVSAPARPAVKAAPAAPAKQQAAAPSTKSAVSVSEPFTPAKQQAAAPFTESVVSVSAPFSPAKQQAAASAKQQAAAPAKQQAAAPAKQQAAAPAKQTNIDFRKDGKNAGIIELAALGFAGQPDISQQHDHIIVTLKNHTLPTTLQRSLDVADFKTPVQKVTLKRLNNDTQLIITTAGNWELVNKSAAPGYFTFQVLPKKQNLESGGVNNAPKTFTGRKISLDFQDVEIRTILQILAKESGMNIVASDSVNGKMTLSLKDVPWDQALDLVMQARNLDMRQQGNIVNIAPRDELLAKDKALLQAEKDIADLGALYSQNFQLKYKNVEEFRSILRLDNADTTGNRNTLISGRGSVLIDPATNTLIVTDTRSVIEKFRKLIDELDVPAQQVMIEARIVEAADGFSRDLGVKFGATGKKKLKNDTSAFGWGVNSGFGGDDKWGAETKINLPITAAANSISLVRAISSGALNLELSASESLSKTKTLANPRVLTQNRKEAKIESGYEIPFTVTSIANGGSSTNTELKKAVLGLTVTPNITPDGQIIMTVKINKDSPAQCASGNQTILCISTKNLNTQAMVENGGTLIVGGIYEEDNGNTLTKVPLLGDIPVIGNLFKTRGKKTDRRELLIFITPRIMGTAGNSLRY
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: pilQ mutant were unable to colonize human nasopharyngeal tissue in an organ culture model (Exley et al., 2009).
Predicted Interacting Host Protein A2BEY5; A6NFU0; A6NGN9; A6NJ16; A6NJ33; A6NJS3; A6NJW9; A6NLU5; A6NMB1; A8K3U1; A8K4G0; A8MQ45; A8MTB9; A8MVW5; A8MVZ5; A8MX21; A8MXK1; B3KTR6; B4DKN2; B4DPU4;
B4DPY3; B4DQ71; B4DT80; B4E2I8; B5MCE1; B5MCX6; B7Z5W1; B8ZZZ4; C9IY66; C9IZX3; C9J0B0; C9J3Q8; C9J795; C9J7D0; C9J877; C9J8J7; C9J8P3; C9J8Z4; C9JBA5; C9JD07;
C9JDD2; C9JGG1; C9JJ79; C9JMW0; C9JMW3; C9JN07; C9JNC3; C9JNZ3; C9JQT8; C9JT30; C9JTE0; C9JUV8; C9JVU4; C9JWP2; C9JXS1; C9JY13; C9JY48; C9JZT5; C9JZW6; D0FY33;
D3YHP0; D6RAK7; D6RBS1; D6RBX9; D6RC59; D6RFI7; D6RG04; D6RGZ6; E5RHN3; E5RIF6; E7ENH0; E7ENV9; E7EQY3; E7EUB1; E7EW65; E7EWP3; E7EX79; E7EX88; E9PC55; E9PF17;
E9PFX0; E9PI25; E9PJA1; E9PJE9; E9PJJ4; E9PJP6; E9PKK2; E9PL79; E9PNS8; E9PR26; E9PRP3; E9PRR1; E9PRX1; F2Z2Y9; F5H125; F5H204; F5H556; F5H724; F8VQJ4; F8W1U8;
F8W1V0; F8W8C9; F8W8J5; F8WBA1; F8WDW9; G3XAA7; G5E978; G5E9F7; H0Y2W6; H0Y8A0; H0YDP1; H0YG94; H0YK40; H0YK59; H0YLT8; H0YM81; H0YN85; H3BML4; H3BRP9; H3BRY4;
H3BT26; H3BTH8; H3BUA5; H3BV43; H7BYC3; H7C1I4; H7C1X1; H7C4F8; H7C4L0; H7C523; H9KV29; H9KVA7; J3KPN5; J3KR39; J3KS52; J3QL19; J3QLM0; J3QQW1; J3QRQ4; K4DIA0;
K7EJW1; K7EKM5; K7EL06; M0QX61; M0QX68; M0QX98; M0QXP2; M0QXR5; M0QXV9; M0QXW0; M0QY31; M0QY44; M0QY65; M0QYF3; M0QYU2; M0QZQ1; M0R0E4; M0R0U8; M0R109; M0R1G9;
M0R235; M0R276; M0R2K4; M0R2P9; M0R363; O00241; O00478; O00481; O14594; O14931; O15389; O43699; O60487; O60500; O60939; O75054; O75144; O75871; O95297; O95727;
O95944; O95976; P01593; P01594; P01595; P01596; P01597; P01598; P01599; P01600; P01601; P01602; P01603; P01604; P01605; P01606; P01607; P01608; P01609; P01610;
P01611; P01612; P01613; P01614; P01615; P01616; P01617; P01619; P01620; P01621; P01622; P01623; P01624; P01625; P01699; P01700; P01701; P01702; P01703; P01704;
P01705; P01706; P01707; P01708; P01709; P01710; P01711; P01712; P01713; P01714; P01715; P01716; P01717; P01718; P01719; P01720; P01721; P01722; P01730; P01732;
P01733; P01737; P01742; P01743; P01744; P01760; P01761; P01762; P01763; P01764; P01765; P01766; P01767; P01768; P01769; P01770; P01771; P01772; P01773; P01774;
P01775; P01776; P01777; P01778; P01779; P01780; P01781; P01782; P01814; P01815; P01816; P01817; P01818; P01824; P01825; P01833; P03979; P04206; P04207; P04208;
P04209; P04211; P04430; P04431; P04432; P04433; P04434; P04435; P04436; P04437; P04438; P06309; P06310; P06311; P06312; P06313; P06314; P06315; P06316; P06317;
P06318; P06319; P06326; P06331; P06729; P06731; P06887; P06888; P06889; P09326; P09564; P10915; P10966; P11464; P11465; P11912; P12018; P13611; P13688; P15151;
P16112; P16410; P18135; P18136; P20138; P23083; P25189; P30530; P31997; P33681; P35968; P40198; P40199; P40259; P42081; P43121; P57087; P78310; P78324; P78410;
P80362; P80419; P80421; P80422; P80748; P83593; Q00887; Q00888; Q00889; Q01151; Q08708; Q08ET2; Q13046; Q13410; Q14002; Q14CZ8; Q15116; Q15223; Q15227; Q15238;
Q15762; Q16557; Q16653; Q2WEN9; Q3KPI0; Q495A1; Q496F6; Q496M1; Q5DTA9; Q5DTB0; Q5DX21; Q5JVN7; Q5JXA8; Q5JXA9; Q5SQ64; Q5SQ65; Q5STM1; Q5SUK5; Q5T2D2; Q5T2L0;
Q5T3I7; Q5T3I8; Q5T3J1; Q5TFQ5; Q5TFQ8; Q5VU13; Q5ZPR3; Q6PID9; Q6UWV2; Q6UX41; Q6UXE8; Q6UXG3; Q6UXG8; Q6UXN2; Q6UXZ3; Q6ZMC9; Q7KYR7; Q7Z692; Q7Z7D3; Q86UW8;
Q86W61; Q86WK6; Q86XK7; Q86YT9; Q8IW00; Q8IWT1; Q8MGR0; Q8N0Z9; Q8N126; Q8N3J6; Q8NFZ8; Q8TAG5; Q8TDQ0; Q8TDQ1; Q8WVV5; Q8WWV6; Q92692; Q93033; Q969P0; Q96AP7;
Q96D42; Q96DU3; Q96GW7; Q96H15; Q96ID5; Q96IQ7; Q96KV6; Q96LC7; Q96N03; Q96NY8; Q96PL5; Q96PQ1; Q96RL6; Q96S86; Q99795; Q9BRK3; Q9BX59; Q9BX67; Q9BY67; Q9BZZ2;
Q9GZV7; Q9H106; Q9H6B4; Q9H7M9; Q9NP99; Q9NQ25; Q9NQS3; Q9NY72; Q9NYZ4; Q9NZC2; Q9NZJ1; Q9NZQ7; Q9P1W8; Q9P2B2; Q9UEL6; Q9UGN4; Q9UIR0; Q9UKI3; Q9UKJ0; Q9UKJ1;
Q9UM44; Q9UPX0; Q9UQ72; Q9UQ74; Q9Y279; Q9Y286; Q9Y336; Q9Y624; R4GND0
COG COG4796U, under U: Intracellular trafficking, secretion, and vesicular transport
References
Exley et al., 2009: Exley RM, Sim R, Goodwin L, Winterbotham M, Schneider MC, Read RC, Tang CM. Identification of meningococcal genes necessary for colonization of human upper airway tissue. Infection and immunity. 2009; 77(1); 45-51. [PubMed: 18936183].