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metF from Neisseria meningitidis MC58

Victor ID 2999
Gene Name metF from Neisseria meningitidis MC58
Sequence Strain (Species/Organism) Neisseria meningitidis MC58
NCBI Gene ID 903063
NCBI Protein GI 15676836
Locus Tag NMB0943
Protein Accession NP_273981.1
Other Database IDs UniProtKB-ID: METF_NEIMB
UniRef100: UniRef100_Q9JZQ3
UniRef90: UniRef90_Q9JZQ3
UniRef50: UniRef50_Q89B13
UniParc: UPI00000C45EA
EMBL: AE002098
EMBL-CDS: AAF41349.1
RefSeq_NT: NC_003112.2
HSSP: P0AEZ1
EnsemblGenome: EBNEIG00000009283
EnsemblGenome_TRS: EBNEIT00000009283
EnsemblGenome_PRO: EBNEIP00000008903
GenomeReviews: AE002098_GR
KEGG: nme:NMB0943
NMPDR: fig|122586.1.peg.915
TIGR: NMB0943
HOGENOM: HBG649727
OMA: ITQMFFD
ProtClustDB: PRK09432
BioCyc: NMEN122586:NMB_0943-MONOMER
Taxonomy ID 122586
Gene Starting Position 956268
Gene Ending Position 957146
Gene Strand (Orientation) +
Protein Name 5,10-methylenetetrahydrofolate reductase
DNA Sequence 
>gi|77358697:956268-957146 Neisseria meningitidis MC58, complete genome
CATGAATTACGCAAAAGAAATCAATGCGTTAAATAACAGCCTTTCCGATTTGAAAGGCGACATCAACGTT
TCATTCGAATTTTTCCCGCCGAAAAACGAACAAATGGAAACCATGCTGTGGGATTCCATCCATCGCCTGC
AAACCTTGCACCCGAAATTTGTTTCCGTAACTTACGGTGCAAACTCAGGCGAGCGCGACCGCACACACGG
CATCGTCAAACGCATCAAACAGGAAACCGGCTTGGAAGCCGCGCCTCACCTGACCGGTATCGACGCTTCT
CCCGACGAATTGCGCCAAATTGCCAAAGATTATTGGGACAGCGGCATCCGCCGCATTGTCGCCCTGCGCG
GAGACGAGCCGGCCGGTTATGAGAAAAAACCGTTTTACGCCGAAGACTTGGTTAAGCTATTACGCTCCGT
CGCCGACTTCGACATCTCTGTAGCAGCATATCCCGAAGTGCATCCCGAAGCGAAATCCGCACAAGCCGAC
CTGATTAATTTGAAACGCAAAATCGATGCGGGCGCGAACCACGTCATCACCCAATTCTTCTTCGATGTGG
AACGCTACCTGCGCTTCCGCGACCGCTGCGTGATGTTGGGTATCGATGTGGAAATCGTCCCCGGTATTTT
GCCTGTTACCAACTTCAAGCAGCTCGGTAAAATGGCTCAAGTAACCAACGTCAAAATCCCAAGCTGGCTG
TCGCAAATGTATGAAGGTTTGGACGACGACCAAGGTACGCGCAATCTGGTGGCGGCAAGTATCGCCATCG
ATATGGTCAAAGTCCTGTCCCGCGAAGGCGTGAAAGATTTCCACTTCTATACGCTTAACCGCAGCGAGCT
GACTTACGCCATTTGCCATATTTTAGGCGTGCGCCCTTA
Protein Sequence 
>gi|15676836|ref|NP_273981.1| 5,10-methylenetetrahydrofolate reductase [Neisseria meningitidis MC58] MNYAKEINALNNSLSDLKGDINVSFEFFPPKNEQMETMLWDSIHRLQTLHPKFVSVTYGANSGERDRTHGIVKRIKQETGLEAAPHLTGIDASPDELRQIAKDYWDSGIRRIVALRGDEPAGYEKKPFYAEDLVKLLRSVADFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANHVITQFFFDVERYLRFRDRCVMLGIDVEIVPGILPVTNFKQLGKMAQVTNVKIPSWLSQMYEGLDDDQGTRNLVAASIAIDMVKVLSREGVKDFHFYTLNRSELTYAICHILGVRP
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: metF mutant is attenuated in rats (Sun et al., 2000).
COG COG0685E, under E: Amino acid transport and metabolism
References
Sun et al., 2000: Sun YH, Bakshi S, Chalmers R, Tang CM. Functional genomics of Neisseria meningitidis pathogenesis. Nature medicine. 2000; 6(11); 1269-1273. [PubMed: 11062540].