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nadA from Neisseria meningitidis MC58

Victor ID 2991
Gene Name nadA from Neisseria meningitidis MC58
Sequence Strain (Species/Organism) Neisseria meningitidis MC58
NCBI Gene ID 902509
NCBI Protein GI 15676308
Locus Tag NMB0394
Protein Accession NP_273443.1
Other Database IDs UniProtKB-ID: NADA_NEIMB
UniRef100: UniRef100_Q9K105
UniRef90: UniRef90_Q5F6I7
UniRef50: UniRef50_B2UAP5
UniParc: UPI000012FC66
EMBL: AE002098
EMBL-CDS: AAF40834.1
RefSeq_NT: NC_003112.2
EnsemblGenome: EBNEIG00000009342
EnsemblGenome_TRS: EBNEIT00000009342
EnsemblGenome_PRO: EBNEIP00000008962
GenomeReviews: AE002098_GR
KEGG: nme:NMB0394
NMPDR: fig|122586.1.peg.377
TIGR: NMB0394
HOGENOM: HBG291157
OMA: IAHPECE
ProtClustDB: PRK09375
BioCyc: NMEN122586:NMB_0394-MONOMER
Taxonomy ID 122586
Gene Starting Position 398425
Gene Ending Position 399537
Gene Strand (Orientation) -
Protein Name quinolinate synthetase
DNA Sequence 
>gi|77358697:398425-399537 Neisseria meningitidis MC58, complete genome
ATCAGGCGGGGCCCATGCCGTTGAACACATCTTTTTTCTTCAGCCCTGCCGCAAAGTCGAGCATACGCTG
CAAAGGCAGTTTGGCGGCTTCGCCCAGCTTCCTGTCCAACAGGATTTCGTTACGTCCGCTTGTCAGGGCG
TATTTGATGCCGCCCAGCGAATTCATCGCCATCCACGGGCAGAACGCGCAGCTTTTACAGCTTCCACCGT
TGCCCGCCGTCGGCGCGGCGATAAATTGTTTGTCGGGCGCCTGCTTTTGCATTTCGTGCAGGATGCCCAA
ATCGGTCGCCACGATGAATTTTTTTTCAGGACGCGATACGGCGGCTTTGAGCAGTTTGCTGGTCGAGCCG
ACCACGTCGCCCAGTTCGATGACGCTTTGCGGCGATTCAGGATGAACCAGCACCACCGCTTCGGGGTGTT
CCGCCTTCAACGCCGCCAGCTCTTGCCCTTTGAATTCGTTGTGAACGATGCACGAACCCTGCCACAACAG
CATATCCGCGCCCGTTTCGCGGCAGATGTAGTCGCCGAGGTGGCGGTCGGGTCCCCAAATCAGCTTCTCG
CCGCGTGATTTCAAATACGATACGATTTCTAACGCCACCGAAGACGTTACCACCCAATCGGCACGCGCTT
TCACGGCGGCGGAAGTGTTGGCGTACACCACCACCGTGCGGTCGGGGTGTTGGTCGCAAAACGCTGAAAA
CGCTTCTTCCGGGCAACCCAAATCCAAAGAACATTCCGCCTCCAAATCAGGCATCAGCACCGTTTTTTCA
GGGCAGAGGATTTTCGCGCTCTCGCCCATGAAGCGCACACCAGCCACCACCAGCGTACCGGCTTCGTGTT
CCGCACCGAAGCGCGCCATTTCCAGCGAATCGCCCACGCATCCGCCCGTCTCCAAAGCCAAATCCTGAAT
CAGCGGATCAACGTAATAATGCGCCACCAAGACCGCGTTTTTCTCCTTCAGCAAAGCCTTGATTTCGTCT
TTCAGACGATCTGCCGTCTCGCGGTCGGGCGTGTCGGCAACCTTCGCCCACGCCTGACGGATTTGGCAGG
CGGAAGTCGGCGTTTGGATGAGTGGCATATCGTAGTCGAACGAGCGGCGGGCGGCGGTTTGCA
Protein Sequence 
>gi|15676308|ref|NP_273443.1| quinolinate synthetase [Neisseria meningitidis MC58] MQTAARRSFDYDMPLIQTPTSACQIRQAWAKVADTPDRETADRLKDEIKALLKEKNAVLVAHYYVDPLIQDLALETGGCVGDSLEMARFGAEHEAGTLVVAGVRFMGESAKILCPEKTVLMPDLEAECSLDLGCPEEAFSAFCDQHPDRTVVVYANTSAAVKARADWVVTSSVALEIVSYLKSRGEKLIWGPDRHLGDYICRETGADMLLWQGSCIVHNEFKGQELAALKAEHPEAVVLVHPESPQSVIELGDVVGSTSKLLKAAVSRPEKKFIVATDLGILHEMQKQAPDKQFIAAPTAGNGGSCKSCAFCPWMAMNSLGGIKYALTSGRNEILLDRKLGEAAKLPLQRMLDFAAGLKKKDVFNGMGPA
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: NadA mutation decreases epithelial adhesion of capsulate N. meningitidis and invasion by acapsulate N. meningitidis (Carbonnelle et al., 2009).
COG COG0379H, under H: Coenzyme transport and metabolism
References
Carbonnelle et al., 2009: Carbonnelle E, Hill DJ, Morand P, Griffiths NJ, Bourdoulous S, Murillo I, Nassif X, Virji M. Meningococcal interactions with the host. Vaccine. 2009; 27 Suppl 2; B78-89. [PubMed: 19481311].