Victors

pilF from Neisseria meningitidis MC58
Victor ID	2989
Gene Name	pilF from Neisseria meningitidis MC58
Sequence Strain (Species/Organism)	Neisseria meningitidis MC58
NCBI Gene ID	902445
NCBI Protein GI	15676245
Locus Tag	NMB0329
Protein Accession	NP_273378.1
Other Database IDs	UniProtKB-ID: Q7DDR2_NEIMB UniRef100: UniRef100_A1KVV5 UniRef90: UniRef90_P37094 UniRef50: UniRef50_P37094 UniParc: UPI00000C4E0C EMBL: AE002098 EMBL-CDS: AAF40773.1 RefSeq_NT: NC_003112.2 EnsemblGenome: EBNEIG00000010679. EnsemblGenome_TRS: EBNEIT00000010679 EnsemblGenome_PRO: EBNEIP00000010299 GenomeReviews: AE002098_GR KEGG: nme:NMB0329 TIGR: NMB0329 HOGENOM: HBG485518 OMA: PLGRREN ProtClustDB: CLSK877498 BioCyc: NMEN122586:NMB_0329-MONOMER
Taxonomy ID	122586
Gene Starting Position	337394
Gene Ending Position	339070
Gene Strand (Orientation)	+
Protein Name	type IV pilus assembly protein
DNA Sequence	>gi\|77358697:337394-339070 Neisseria meningitidis MC58, complete genome TATGAGCGTAGGTTTGCTGAGGATTCTGGTTCAAAACCAGGTGGTTACTGTTGAGCAGGCCGAGCATTAC TACAATGAGTCGCAGGCGGGTAAGGAAGTGTTGCCGATGCTGTTTTCAGACGGTGTCATTTCGCCCAAGT CGCTTGCGGCATTGATTGCGAGGGTGTTCAGTTATTCGATTCTTGATTTGCGTCATTATCCGCGCCACAG GGTGCTGATGGGGGTGTTGACGGAGGAGCAGATGGTGGAGTTCCACTGTGTGCCGGTTTTCCGTCGGGGC GACAAAGTATTTTTTGCGGTTTCCGATCCGACACAGATGCCGCAAATTCAGAAAACCGTTTCTGCCGCAG GGATTGAGGTTGAGTTGGTCATTGTCGAGGATGACCAGTTGGCGGGTTTGCTCGATTGGGTGGGTTCGCG TTCGACATCGCTGCTTCAGGAGCTTGGGGAGGGGCAGGAGGAAGAGGAAAGCCACACCCTGTATATCGAC AACGAGGAGGCAGAAGACGGCCCTGTTCCGAGGTTTATCCATAAGACTTTGTCGGATGCCTTGCGCAGCG GGGCATCGGACATCCATTTCGAGTTTTACGAACACAATGCCCGTATCCGTTTCCGTGTGGACGGGCAGCT CCGCGAGGTGGTTCAGCCGCCCATTGCGGTAAGGGGGCAGCTTGCTTCACGGATTAAGGTAATGTCGCGT TTGGACATTTCCGAAAAACGGATACCGCAGGACGGCAGGATGCAGCTGACCTTTCAAAAGGGCGGCAAGC CTGTCGATTTCCGTGTCAGCACATTGCCGACGCTGTTTGGCGAAAAGGTCGTGATGCGGATTTTGAATTC CGATGCCGCGTCTTTGAACATCGACCAGCTCGGTTTTGAGCCGTTTCAGAAAAAATTGTTGTTGGAAGCG ATTCACCGTCCCTACGGGATGGTGCTGGTAACCGGTCCGACGGGTTCGGGTAAGACGGTGTCGCTCTATA CCTGTTTGAATATTTTGAATACGGAGTCGGTAAATATTGCAACGGCGGAAGACCCTGCCGAGATTAACCT GCCGGGCATCAATCAGGTTAACGTCAATGATAAGCAGGGCCTGACTTTTGCCGCTGCTTTGAAGTCTTTC CTGCGTCAGGACCCGGACATCATTATGGTCGGTGAGATTCGTGATTTGGAAACTGCCGATATTGCGATTA AGGCGGCACAAACAGGGCATATGGTGTTTTCCACCCTGCACACCAATAATGCGCCGGCGACGTTGTCGCG TATGCTGAATATGGGTGTCGCGCCGTTTAATATTGCCAGTTCGGTCAGCCTGATTATGGCGCAGCGTCTT TTACGCAGGCTGTGTTCGAGCTGCAAACAGGAAGTGGAACGCCCGTCTGCCTCTGCTTTGAAGGAAGTCG GCTTCACCGATGAGGACCTTGCAAAAGATTGGAAACTTTACCGCGCCGTCGGTTGCGACCGTTGCCGGGG GCAGGGTTATAAGGGGCGTGCGGGCGTGTATGAGGTTATGCCCATCAGCGAAGAAATGCAGCGTGTGATT ATGAACAACGGTACGGAAGTGGATATTTTGGACGTTGCCTATAAGGAGGGTATGGTGGATTTGCGCCGGG CCGGTATTTTGAAAGTTATGCAGGGCATTACTTCATTGGAAGAGGTAACGGCAAATACCAACGATTA
Protein Sequence	>gi\|15676245\|ref\|NP_273378.1\| type IV pilus assembly protein [Neisseria meningitidis MC58] MSVGLLRILVQNQVVTVEQAEHYYNESQAGKEVLPMLFSDGVISPKSLAALIARVFSYSILDLRHYPRHRVLMGVLTEEQMVEFHCVPVFRRGDKVFFAVSDPTQMPQIQKTVSAAGIEVELVIVEDDQLAGLLDWVGSRSTSLLQELGEGQEEEESHTLYIDNEEAEDGPVPRFIHKTLSDALRSGASDIHFEFYEHNARIRFRVDGQLREVVQPPIAVRGQLASRIKVMSRLDISEKRIPQDGRMQLTFQKGGKPVDFRVSTLPTLFGEKVVMRILNSDAASLNIDQLGFEPFQKKLLLEAIHRPYGMVLVTGPTGSGKTVSLYTCLNILNTESVNIATAEDPAEINLPGINQVNVNDKQGLTFAAALKSFLRQDPDIIMVGEIRDLETADIAIKAAQTGHMVFSTLHTNNAPATLSRMLNMGVAPFNIASSVSLIMAQRLLRRLCSSCKQEVERPSASALKEVGFTDEDLAKDWKLYRAVGCDRCRGQGYKGRAGVYEVMPISEEMQRVIMNNGTEVDILDVAYKEGMVDLRRAGILKVMQGITSLEEVTANTND
Molecule Role	Virulence factor
Molecule Role Annotation	MUTATION: pilF mutant were unable to colonize human nasopharyngeal tissue in an organ culture model (Exley et al., 2009).
COG	COG2804NU, under N: Cell motility; U: Intracellular trafficking, secretion, and vesicular transport
References	*Exley et al., 2009:* Exley RM, Sim R, Goodwin L, Winterbotham M, Schneider MC, Read RC, Tang CM. Identification of meningococcal genes necessary for colonization of human upper airway tissue. Infection and immunity. 2009; 77(1); 45-51. [PubMed: 18936183].


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pilF from Neisseria meningitidis MC58