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lpxA

Victor ID 2986
Gene Name lpxA
Sequence Strain (Species/Organism) Neisseria meningitidis MC58
NCBI Gene ID 902285
NCBI Protein GI 15676105
Locus Tag NMB0178
Protein Accession NP_273236.1
Other Database IDs UniProtKB-ID: LPXA_NEIMB
UniRef100: UniRef100_P95379
UniRef90: UniRef90_Q5F5W3
UniRef50: UniRef50_Q5F5W3
UniParc: UPI000005109E
EMBL: U79481
EMBL: AE002098
EMBL-CDS: AAC45424.1
EMBL-CDS: AAF40635.1
RefSeq_NT: NC_003112.2
EnsemblGenome: EBNEIG00000010785
EnsemblGenome_TRS: EBNEIT00000010785
EnsemblGenome_PRO: EBNEIP00000010405
GenomeReviews: AE002098_GR
KEGG: nme:NMB0178
NMPDR: fig|122586.1.peg.170
TIGR: NMB0178
HOGENOM: HBG659295
OMA: GHTSIGE
ProtClustDB: PRK05289
BioCyc: NMEN122586:NMB_0178-MON
Taxonomy ID 122586
Gene Starting Position 175428
Gene Ending Position 176204
Gene Strand (Orientation) -
Protein Name UDP-N-acetylglucosamine acyltransferase
DNA Sequence 
>gi|77358697:175428-176204 Neisseria meningitidis MC58, complete genome
GTCAGCGGATGATGCCGCGCGCCGATTGTGCGAAAAAGTCTCGGAATACGGCAAGCTCGGCTTGGGTTTC
GGCGCGGCGGAGAATGTCTGCCTTGGCTTCTTCAAACGGAATGCCGCGATGGTAGAGGGTTTTGTACACG
TCTTTGACGGCGGAAATCTGCTCTGCGGTAAAACCGTTGCGGCGCATGCCTTCGCTGTTGAGCCCCGCCG
GTTCGGCGCGGTAGCCCGATGCCATAAAGTAGGGCGGCACGTCTTTGTGTACGCCTGCGGCAAACGCGGT
CATGGCGTAGTCGCCGATGCGGCAGAATTGGAAAACCAGCGTGTAGCCGCCCAAAACGACGTAGTCGCCG
ATGGTAACGTGTCCGGCAAGCGAGGCGTTGTTGGCGAAAATGGTGTGGTTGCCGATGACGCAGTCGTGCG
CGAGGTGGCAGTACGCCATAATCCAGTTGTCGTCGCCGATACGGGTTTCGCCGATGCCGGTTACCGTACC
TAAATTAAAGGTGGTGAATTCGCGGATGGTGTTGCCGTTGCCGATAATCAGCTTGGTCGGCTCGTCGCGG
TATTTTTTGTCCTGCGGGATTTCGCCGAGGCTGGCAAATTGGAAAATGCGGTTGTTTTCGCCGATGCTGG
TGTGGCCGTTGATGACGGCGTGCGGACCGATTTCGGTATTCGCGCCGATTTGGACGTTGGGGCCGATAAC
GGTGTACGCGCCGACTTTGACGCCGGAGTCGAGTTCGGCTTTGGGGTCGATGACGGCGGTCGGGTGGATG
AGGGTCA
Protein Sequence 
>gi|15676105|ref|NP_273236.1| UDP-N-acetylglucosamine acyltransferase [Neisseria meningitidis MC58] MTLIHPTAVIDPKAELDSGVKVGAYTVIGPNVQIGANTEIGPHAVINGHTSIGENNRIFQFASLGEIPQDKKYRDEPTKLIIGNGNTIREFTTFNLGTVTGIGETRIGDDNWIMAYCHLAHDCVIGNHTIFANNASLAGHVTIGDYVVLGGYTLVFQFCRIGDYAMTAFAAGVHKDVPPYFMASGYRAEPAGLNSEGMRRNGFTAEQISAVKDVYKTLYHRGIPFEEAKADILRRAETQAELAVFRDFFAQSARGIIR
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: lpxA mutant is attenuated in mice (Zarantonelli et al., 2006).
COG COG1043M, under M: Cell wall/membrane/envelope biogenesis
References
Zarantonelli et al., 2006: Zarantonelli ML, Huerre M, Taha MK, Alonso JM. Differential role of lipooligosaccharide of Neisseria meningitidis in virulence and inflammatory response during respiratory infection in mice. Infection and immunity. 2006; 74(10); 5506-5512. [PubMed: 16988225].