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ilvD from Neisseria meningitidis Z2491

Victor ID 2976
Gene Name ilvD from Neisseria meningitidis Z2491
Sequence Strain (Species/Organism) Neisseria meningitidis Z2491
NCBI Gene ID 907768
NCBI Protein GI 15794282
Locus Tag NMA1361
Protein Accession NP_284104.1
Other Database IDs UniProtKB-ID: ILVD_NEIMA
UniRef100: UniRef100_Q9JUE0
UniRef90: UniRef90_Q5F8G6
UniRef50: UniRef50_Q5F8G6
UniParc: UPI00000445CE
EMBL: AL157959
EMBL-CDS: CAM08534.1
RefSeq_NT: NC_003116.1
EnsemblGenome: EBNEIG00000000586
EnsemblGenome_TRS: EBNEIT00000000586
EnsemblGenome_PRO: EBNEIP00000000586
GenomeReviews: AL157959_GR
KEGG: nma:NMA1361
HOGENOM: HBG671001
OMA: KVPCLSK
ProtClustDB: PRK12448
BioCyc: NMEN122587:NMA1361-MONOMER
Taxonomy ID 122587
Gene Starting Position 1257348
Gene Ending Position 1259207
Gene Strand (Orientation) -
Protein Name dihydroxy-acid dehydratase
DNA Sequence 
>gi|15793034:1257348-1259207 Neisseria meningitidis Z2491, complete genome
CTTATCTTTCGATTTGCGCTACGTCGCGCACCGCGCCTTTGTCGGCGGAAGTCGCCATCGCGCCGTAAGC
TCTTAATGCGGCGGAGACGTAGCGGTCGCGGTTTTCCGGTTTCCACGCTTTGCTGCCGCGTGCTTCCATT
TCGGCACGGCGGGCGGCGAGTTCTTCGTCGGAAATGACAAGGCGGATGCTGCGGTTGGGGATGTCGATTT
CGACGGTATCGCCTTCGTGTACCAAACCGATCGCGCCACCTTCCGCCGCTTCGGGCGAGGCGTGTCCGAT
GGACAAACCTGATGTGCCGCCGGAGAAGCGTCCGTCGGTTAAGAGAGCGCAGGCTTTGCCGAGGCCTTTA
GATTTCAGGTAGGAAGTCGGATACAGCATTTCCTGCATGCCCGGGCCGCCTTTCGGGCCTTCGTAGCGGA
TGATGACGATGTCGCCGGCGACGATTTGGTTGCCCAAAATGCCTTCTACTGCGTCTTCTTGGCTTTCAAA
CACGCGGGCGCGGCCGGTGAATTTGAGGATGCTCTCGTCCACGCCTGCGGTTTTTACCACGCAGCCGCGC
TCGGCGATGTTGCCGAACAAGACCGCCAAACCGCCGTCTTGCGAGTAGGCGTGTGCCACGTCGCGGATAC
AGCCTTTTTCGCGGTCGAGGTCGAGGGTTTTCCACATACGGTTTTGCGAGAACGCTTGGGTGGTGCGTAC
GCCGCCGGGCGCGGCTTTGAAGCGTTCGATGGCGTGGGTGTTTTCAGGGTTGGTTACGTCCCATTTTTCA
ATCGCGTCTTTCAGCGTCGGCGCGTGGATAGTGTGCACGTCGGTGTGCAGCTTGCCCGCTTTGTCCAATT
CTTTCAGGATGGCGAAGATGCCGCCGGCTCGGTGCACGTCTTCCATATAGTAGTCGTGGTTGTTGGGTGC
GGTTTTGCAGATGCAGGGCACAACGCGGCTTAAGCGGTCGATGTCTGCCATTTTGAAATCCACGCCCGCT
TCGTTGGCAACGGCGAGTAAATGCAAAATAGTGTTGGTGCTGCCGCCCATGGCAATGTCCATGGTCATAG
CGTTTTCAAACGCTTTTTTGGTGGCAATGCTGCGCGGTAACACGGTTTCATCGTTTTGCTCGTAATAGCG
TTTGGTGATTTCGACAATCATACGGCCGGCTTCGAGGAACAGTTCTTTGCGGCCGACGTGGGTGGCGAGG
TAAGAACCGTTGCCCGGCAGGGACAGCCCGAGTGCTTCGGTCAGGCAGTTCATCGAGTTTGCCGTAAACA
TACCCGAACACGAGCCGCAGGTCGGGCAGGCGTTTTGTTCGACTTCTTCAACTTGCCGGTTGCTGATATT
GTCGTCCGCCGATTCAATCATCGCGTCAATCAAGTCCAAACGGCGTTCGGGCTGGATGTTTGCCACGCCG
ATAACTTTACCTGCTTCCATCGGACCGCCGGAAACGAAGATGGTCGGGATGTTCAGGCGCATCGCGGCAA
TCAGCATGCCCGGGGTGATTTTGTCGCAGTTGGAAATGCACACCAGCGCGTCGGCGCAGTGGGCATTGAC
CATATATTCGATGGAGTCGGCAATCAAATCGCGGCTGGGCAGGGAATACAGCATACCGCTGTGTCCCATA
GCGATGCCGTCGTCGATGGCGATGGTGTTGAATTCTTTGGCGATGGCGCCGGCTTTTTCGATTTCGCGGG
CAACCAGCTGGCCCATATTGTGCAGGTGGACATGACCTGGCACGAATTGGGTGAACGAGTTGGCAACGGC
GATAATCGGTTTGCCGAAGTCGGTTTCCATCACGCCGGTGGCGCGCCACAACGCGCGCGCGCCCGCCATA
TTGCGACCGTGGGTGGAGGTTTTGGAGCGGTATTCTGGCA
Protein Sequence 
>gi|218768203|ref|YP_002342715.1| dihydroxy-acid dehydratase [Neisseria meningitidis Z2491] MPEYRSKTSTHGRNMAGARALWRATGVMETDFGKPIIAVANSFTQFVPGHVHLHNMGQLVAREIEKAGAIAKEFNTIAIDDGIAMGHSGMLYSLPSRDLIADSIEYMVNAHCADALVCISNCDKITPGMLIAAMRLNIPTIFVSGGPMEAGKVIGVANIQPERRLDLIDAMIESADDNISNRQVEEVEQNACPTCGSCSGMFTANSMNCLTEALGLSLPGNGSYLATHVGRKELFLEAGRMIVEITKRYYEQNDETVLPRSIATKKAFENAMTMDIAMGGSTNTILHLLAVANEAGVDFKMADIDRLSRVVPCICKTAPNNHDYYMEDVHRAGGIFAILKELDKAGKLHTDVHTIHAPTLKDAIEKWDVTNPENTHAIERFKAAPGGVRTTQAFSQNRMWKTLDLDREKGCIRDVAHAYSQDGGLAVLFGNIAERGCVVKTAGVDESILKFTGRARVFESQEDAVEGILGNQIVAGDIVIIRYEGPKGGPGMQEMLYPTSYLKSKGLGKACALLTDGRFSGGTSGLSIGHASPEAAEGGAIGLVHEGDTVEIDIPNRSIRLVISDEELAARRAEMEARGSKAWKPENRDRYVSAALRAYGAMATSADKGAVRDVAQIER
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: ilvD mutant is attenuated in rats (Sun et al., 2000).
References
Sun et al., 2000: Sun YH, Bakshi S, Chalmers R, Tang CM. Functional genomics of Neisseria meningitidis pathogenesis. Nature medicine. 2000; 6(11); 1269-1273. [PubMed: 11062540].