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ilvI from Neisseria meningitidis Z2491

Victor ID 2975
Gene Name ilvI from Neisseria meningitidis Z2491
Sequence Strain (Species/Organism) Neisseria meningitidis Z2491
NCBI Gene ID 907658
NCBI Protein GI 15794659
Locus Tag NMA1766
Protein Accession NP_284481.1
Other Database IDs UniProtKB-ID: A1ISY1_NEIMA
UniRef100: UniRef100_A1ISY1
UniRef90: UniRef90_B4RJ12
UniRef50: UniRef50_Q89AP7
UniParc: UPI00000445CF
EMBL: AL157959
EMBL-CDS: CAM08893.1
RefSeq_NT: NC_003116.1
EnsemblGenome: EBNEIG00000001398.
EnsemblGenome_TRS: EBNEIT00000001398
EnsemblGenome_PRO: EBNEIP00000001398
GenomeReviews: AL157959_GR
KEGG: nma:NMA1766
HOGENOM: HBG323037
OMA: ANLAMQN
ProtClustDB: CLSK878135
Taxonomy ID 122587
Gene Starting Position 1709993
Gene Ending Position 1711720
Gene Strand (Orientation) -
Protein Name acetolactate synthase isozyme III large subunit
DNA Sequence 
>gi|15793034:1709993-1711720 Neisseria meningitidis Z2491, complete genome
CTTACGCCTTTCCGTCCGCACGCATATGCGGCGGAAGTACCATTTCGTCCAAACCTTTGCCGTTGCCGAC
CATGGGCATCACATTCTGTTTCTGGTCGGTCAGGAAGTCGATAAACACCAGCCTGTCTTTTTGGTTCAAT
GCTTCCAACAACGCACCTTCCACATCAGACTTCTTGTCCACGCGGATACCGATATGGCCGTATGCCTCGG
CAAGTTTGACGAAATCGGGCAAAGAATCGAAATAGGTTTCCGACTCTCGTCCGCCGTAATATATTTCCTG
CCACTGGCGTACCATACCGAGATAACCGTTGTTCAGCGTAATGACGTTAACCGGAATCCGATATTGGAAA
CAGGTGGACAGCTCTTGGATGTTCATCTGGATCGAGCCGTCGCCGGTAATACAGAATACGTCTTGATCCG
GGGCGGCAAGTTTTGCACCAATCGCATAAGGCAGACCAACGCCCATCGTACCCAAACCGCCGGAGTTGAG
CCATTGGCGCGGACGTTCGAAGGGATAATATTGAGCCGCAAACATTTGATGCTGCCCTACATCCGATGTG
ATGATTGCCGAATTGCCGGTAATCTCGGCAAGCTTCTGAATCACATATTGTGGCTTGATAATTTCGCTGC
CGTTGTCAAACCACAAGCAATCGCGGGAACGCCATTCCTCTATGGTTTTCCACCATTTGCCCAAAGCATC
TTCAGACGGCACGGACTCTTGTTTTTGCCACAGCGCAACCATCTCGGACAAAACGTTTTTCACGTCGCCG
ACAATCGGAATGTCCGCCTTCACGCGTTTGGCGATGCTGGAAGGATCGACATCGATATGGATAACCTTCT
TCGCCTTCTCGAAAAATTTGGACGGTACGGAAACCACACGGTCGTCAAAACGCGCACCTACGGCAAGAAC
GACATCCGCATTCTGCATGGCAAGGTTTGCCTCGTAAGTACCGTGCATACCGAGCATACCGAGGAATTGG
CGGTCGCCGGAAGGATAAGCGCCCAAGCCCATCAGCGTACCCGTGCACGGAGCACCCGTCATTCGGACAA
ATCGGGTCAGCTCTTCAGAAGCATTACCCAACACCACGCCGCCGCCAAAATAGACGACCGGACGTTTGGC
AGATGCCAACATCTGCACGGCCTTTTTAATCTGACCGATATGCCCTTGAACAACCGGTTGATACGAACGG
ATAAAAATGTCTTCCTGAGGATAGCTGAATTTCGCCATCGCCTGCGTAACATCTTTCGGGACATCAACCA
CCACGGGCCCCGGTCGGCCGCTTGCGGCAATTTGGAACGCCTTTTTAATGGTTTCCGCCAACTCATTGAT
GTCCGTAACCAGGAAATTGTGTTTGACGCACGGACGGGTAATACCCACCGTATCAACTTCTTGGAACGCA
TCCGTACCAATCAGGGAATTGCCTACCTGCCCGCTGATGACCACCATCGGAATCGAATCCGTATAGGCAG
TAGCAATACCGGTCAGTGCATTGGTAACGCCCGGGCCGGATGTAACCAATGCCACGCCCACCTTACCGCT
GACGCGCGCATACGCATCTGCCGCGTGTACTGCCGCCTGCTCGTGACGGGTCAGAATGTGCTTGAATTTA
TTGAGTTGGAAAAGGGCATCGTAGATTTCGATAACCGCACCGCCGGGATAACCGAAAACGTACTCGACAC
CTTCGGCTTTGAGACTCTGCACTATGATTTGCGCGCCTGATAGCTGCA
Protein Sequence 
>gi|218768545|ref|YP_002343057.1| acetolactate synthase isozyme III large subunit [Neisseria meningitidis Z2491] MQLSGAQIIVQSLKAEGVEYVFGYPGGAVIEIYDALFQLNKFKHILTRHEQAAVHAADAYARVSGKVGVALVTSGPGVTNALTGIATAYTDSIPMVVISGQVGNSLIGTDAFQEVDTVGITRPCVKHNFLVTDINELAETIKKAFQIAASGRPGPVVVDVPKDVTQAMAKFSYPQEDIFIRSYQPVVQGHIGQIKKAVQMLASAKRPVVYFGGGVVLGNASEELTRFVRMTGAPCTGTLMGLGAYPSGDRQFLGMLGMHGTYEANLAMQNADVVLAVGARFDDRVVSVPSKFFEKAKKVIHIDVDPSSIAKRVKADIPIVGDVKNVLSEMVALWQKQESVPSEDALGKWWKTIEEWRSRDCLWFDNGSEIIKPQYVIQKLAEITGNSAIITSDVGQHQMFAAQYYPFERPRQWLNSGGLGTMGVGLPYAIGAKLAAPDQDVFCITGDGSIQMNIQELSTCFQYRIPVNVITLNNGYLGMVRQWQEIYYGGRESETYFDSLPDFVKLAEAYGHIGIRVDKKSDVEGALLEALNQKDRLVFIDFLTDQKQNVMPMVGNGKGLDEMVLPPHMRADGKA
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: ilvI mutant is attenuated in rats (Sun et al., 2000).
References
Sun et al., 2000: Sun YH, Bakshi S, Chalmers R, Tang CM. Functional genomics of Neisseria meningitidis pathogenesis. Nature medicine. 2000; 6(11); 1269-1273. [PubMed: 11062540].