Search: for Help
About
Introduction
Statistics
Your PHIDIAS
Register or Login
Philert
Submission
Curated Data
Victors
BBP (Brucella)
Phinfo
Phinet
HazARD
Data Analysis
Phigen
Pacodom
BLAST
Help & Documents
Documents
FAQs
Links
Acknowledgements
Disclaimer
Contact Us
UMMS Logo

tonB

Victor ID 2968
Gene Name tonB
Sequence Strain (Species/Organism) Neisseria meningitidis
NCBI Gene ID 907455
NCBI Protein GI 15794867
Locus Tag NMA1985
Protein Accession NP_284689.1
Other Database IDs UniProtKB-ID: TONB_NEIMA
UniRef100: UniRef100_P57003
UniRef90: UniRef90_O06432
UniRef50: UniRef50_O06432
UniParc: UPI00000445EA
EMBL: AL157959
EMBL-CDS: CAM09094.1
RefSeq_NT: NC_003116.1
EnsemblGenome: EBNEIG00000001341
EnsemblGenome_TRS: EBNEIT00000001341
EnsemblGenome_PRO: EBNEIP00000001341
GenomeReviews: AL157959_GR
KEGG: nma:NMA1985
HOGENOM: HBG134785
OMA: NEINAYK
ProtClustDB: CLSK878208
BioCyc: NMEN122587:NMA1985-MONOMER
Taxonomy ID 122587
Gene Starting Position 1924632
Gene Ending Position 1925474
Gene Strand (Orientation) -
Protein Name TonB protein
DNA Sequence 
>gi|15793034:1924632-1925474 Neisseria meningitidis Z2491, complete genome
CCTAATTCAATTCAAACTTGACGGGGACTTTAAACTCCGTCCAGGCATTGGCTTGAAAATGCCCGTTTTG
CGCCGCCTTGCGTGCCGCATTGTCCAACCGGGAAAAACCACTGCTTTTCACGATTTTAACGGACTCAACA
TGACCGCCCGGAGAAACCAAAACGCTCAAAACAACCGTACCCTGCTCATCATTCTCCATAGAAAGCGTGG
GATAAGCCGGGCGCGGAATGCTGCCGTTGGCGCGTAAAGGATTGCCTTTGCTGCTGCCGGCTCCTTCCCC
GTGTTCGCCTTTGACACCGCCGCTACCTTTACCGCTGCCTTCTCCGCGCCCCGTTCCGTCTCCTTTGATA
CCGGTTCCCTTATCTTCCCCATTGCCCTGCTCGCTGTCTGCTTTGGCAGAAGCATTGCCGGGATGTTCGG
CAGGTTTTTCAGACGGCTTCTCGACCGGTTTTTCCGCCGGTTTCGGGACAGGCTTCGCTTCCGGCTTAGG
CTCTGGTTTCGGTTTTTCTTCGGGTTTCGGCTTTTCTTCAGGTTTCGGCTCTTCCTTAGGCTGCTGAATA
TCCGCATCCGCCTTTTTCGTAACCACCGGCTTCAAAACCGGCTTGGGCGGCTCGACAGGTTTGGGCGGCT
CGGGCACGGGTTGCGGTTCGGGCGCGGCAGGCGCGCCTGCACCTTCGGGTGCGCCGTCCCCTCCGCCAAA
ATCGCCCAAATCGACAAATTCAATAACATTGCCTGACTCTATCACGGGCAGCTTGTGCGCCTGCCAGAGC
AATGCCACCATTGCCAAATGCAGCAGTGCGACGGAAAACACGACTGCGGGGGTTAAAATTCGTTCTTTAT
CCA
Protein Sequence 
>gi|218768742|ref|YP_002343254.1| TonB protein [Neisseria meningitidis Z2491] MDKERILTPAVVFSVALLHLAMVALLWQAHKLPVIESGNVIEFVDLGDFGGGDGAPEGAGAPAAPEPQPVPEPPKPVEPPKPVLKPVVTKKADADIQQPKEEPKPEEKPKPEEKPKPEPKPEAKPVPKPAEKPVEKPSEKPAEHPGNASAKADSEQGNGEDKGTGIKGDGTGRGEGSGKGSGGVKGEHGEGAGSSKGNPLRANGSIPRPAYPTLSMENDEQGTVVLSVLVSPGGHVESVKIVKSSGFSRLDNAARKAAQNGHFQANAWTEFKVPVKFELN
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: tonB mutant is unable to replicate within human epithelial cells (Larson et al., 2002).
References
Larson et al., 2002: Larson JA, Higashi DL, Stojiljkovic I, So M. Replication of Neisseria meningitidis within epithelial cells requires TonB-dependent acquisition of host cell iron. Infection and immunity. 2002; 70(3); 1461-1467. [PubMed: 11854233].