Search: for Help
About
Introduction
Statistics
Your PHIDIAS
Register or Login
Philert
Submission
Curated Data
Victors
BBP (Brucella)
Phinfo
Phinet
HazARD
Data Analysis
Phigen
Pacodom
BLAST
Help & Documents
Documents
FAQs
Links
Acknowledgements
Disclaimer
Contact Us
UMMS Logo

nadA from Neisseria meningitidis Z2491

Victor ID 2967
Gene Name nadA from Neisseria meningitidis Z2491
Sequence Strain (Species/Organism) Neisseria meningitidis Z2491
NCBI Gene ID 907353
NCBI Protein GI 15794965
Locus Tag NMA2090
Protein Accession NP_284787.1
Other Database IDs UniProtKB-ID: NADA_NEIMA
UniRef100: UniRef100_Q9JSX6
UniRef90: UniRef90_Q5F6I7
UniRef50: UniRef50_B2UAP5
UniParc: UPI000012FC65
EMBL: AL157959
EMBL-CDS: CAM09191.1
RefSeq_NT: NC_003116.1
EnsemblGenome: EBNEIG00000000954
EnsemblGenome_TRS: EBNEIT00000000954
EnsemblGenome_PRO: EBNEIP00000000954
GenomeReviews: AL157959_GR
KEGG: nma:NMA2090
HOGENOM: HBG291157
OMA: IAHPECE
ProtClustDB: PRK09375
BioCyc: NMEN122587:NMA2090-MONOMER
Taxonomy ID 122587
Gene Starting Position 2042838
Gene Ending Position 2043950
Gene Strand (Orientation) +
Protein Name quinolinate synthetase
DNA Sequence 
>gi|15793034:2042838-2043950 Neisseria meningitidis Z2491, complete genome
CATGCAAACCGCCGCCCGCCGCTCGTTCGATTACGATATGCCACTCATCCAAACGCCGACTTCCGCCTGC
CAAATCCGTCAGGCGTGGGCGAAGGTTGCCGACACGCCCGACCGCGAGACGGCAGATCGTCTGAAAGACG
AAATCAAGGCCTTGCTGAAGGAGACAAACGCGGTCTTGGTGGCGCATTATTACGTTGATCCGCTGATTCA
GGATTTGGCTTTGGAGACGGGCGGATGCGTGGGCGATTCGCTGGAAATGGCGCGCTTCGGTGCGGAACAC
GAAGCCGGTACGCTGGTGGTGGCTGGTGTGCGCTTCATGGGCGAGAGCGCGAAAATCCTCTGCCCTGAAA
AAACGGTGCTGATGCCTGATTTGGAGGCGGAATGTTCTTTGGATTTGGGTTGCCCGGAAGAAGCGTTTTC
AGCGTTTTGCGACCAACACCCCGACCGCACGGTGGTGGTGTACGCCAACACTTCCGCCGCCGTGAAAGCG
CGTGCCGATTGGGTGGTAACGTCTTCGGTGGCGTTAGAAATCGTATCGTATTTGAAATCACGCGGCGAGA
AGCTGATTTGGGGACCCGACCGCCACCTCGGCGACTACATCTGCCGCGAAACGGGCGCGGATATGCTGTT
GTGGCAGGGTTCGTGCATCGTCCACAACGAATTTAAAGGGCAGGAGCTGGCGGCGTTGAAAGCGGAACAT
CCCGACGCGGTGGTGCTGGTTCATCCCGAATCGCCGCAAAGCGTCATCGAACTGAGCGACGTGGTCGGCT
CGACCAGCAAACTGCTCAAAGCCGCCGTATCGCGTCCTGAAAAAAAATTCATCGTGGCGACCGATTTGGG
CATCCTGCACGAAATGCAAAAGCAGGCGCCCGACAAACAATTTATCGCCGCGCCGACGGCGGGCAACGGT
GGAAGCTGTAAAAGCTGCGCGTTCTGCCCGTGGATGGCGATGAATTCGCTGGGCGGCATCAAATACGCCC
TGACAAGCGGACGTAACGAAATCCTGTTGGACAGGAAGCTGGGCGAAGCCGCCAAACTGCCTTTGCAGCG
TATGCTCGACTTCGCGGCAGGACTCAAACGCGGGGATGTGTTCAACGGCATGGGTCCCGCCTG
Protein Sequence 
>gi|218768833|ref|YP_002343345.1| quinolinate synthetase [Neisseria meningitidis Z2491] MQTAARRSFDYDMPLIQTPTSACQIRQAWAKVADTPDRETADRLKDEIKALLKETNAVLVAHYYVDPLIQDLALETGGCVGDSLEMARFGAEHEAGTLVVAGVRFMGESAKILCPEKTVLMPDLEAECSLDLGCPEEAFSAFCDQHPDRTVVVYANTSAAVKARADWVVTSSVALEIVSYLKSRGEKLIWGPDRHLGDYICRETGADMLLWQGSCIVHNEFKGQELAALKAEHPDAVVLVHPESPQSVIELSDVVGSTSKLLKAAVSRPEKKFIVATDLGILHEMQKQAPDKQFIAAPTAGNGGSCKSCAFCPWMAMNSLGGIKYALTSGRNEILLDRKLGEAAKLPLQRMLDFAAGLKRGDVFNGMGPA
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: NadA mutation decreases epithelial adhesion of capsulate N. meningitidis and invasion by acapsulate N. meningitidis (Carbonnelle et al., 2009).
References
Carbonnelle et al., 2009: Carbonnelle E, Hill DJ, Morand P, Griffiths NJ, Bourdoulous S, Murillo I, Nassif X, Virji M. Meningococcal interactions with the host. Vaccine. 2009; 27 Suppl 2; B78-89. [PubMed: 19481311].