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fhs from Neisseria meningitidis Z2491

Victor ID 2954
Gene Name fhs from Neisseria meningitidis Z2491
Sequence Strain (Species/Organism) N eisseria meningitidis Z2491
NCBI Gene ID 906612
NCBI Protein GI 15793607
Locus Tag NMA0617
Protein Accession NP_283429.1
Other Database IDs UniProtKB-ID: FTHS_NEIMA
UniRef100: UniRef100_Q9JVY8
UniRef90: UniRef90_Q5FAG1
UniRef50: UniRef50_Q2RM91
UniParc: UPI00000445F1
EMBL: AL157959
EMBL-CDS: CAM07883.1
RefSeq_NT: NC_003116.1
EnsemblGenome: EBNEIG00000001092
EnsemblGenome_TRS: EBNEIT00000001092
EnsemblGenome_PRO: EBNEIP00000001092
GenomeReviews: AL157959_GR
KEGG: nma:NMA0617
HOGENOM: HBG677721
OMA: KMPGLPK
ProtClustDB: PRK13505
BioCyc: NMEN122587:NMA0617-MONOMER
Taxonomy ID 122587
Gene Starting Position 592875
Gene Ending Position 594551
Gene Strand (Orientation) +
Protein Name formate--tetrahydrofolate ligase
DNA Sequence 
>gi|15793034:592875-594551 Neisseria meningitidis Z2491, complete genome
CATGAGTTTCAAAACCGATGCCGAAATCGCCCAATCCTCCACCATGCGCCCGATTGGCGAAATTGCCGCC
AAGCTGGGTTTGAACGTTGACAACATTGAGCCTTACGGTCATTACAAAGCCAAAATCAATCCTGCCGAAG
CGTTCAAACTGCCGCAAAAACAGGGCAGGCTGATTTTGGTTACCGCCATCAACCCGACTCCGGCGGGCGA
AGGTAAAACCACCGTAACCATCGGTTTGGCGGACGCATTGCGCCATATCGGCAAAGACTCTGTGATTGCT
TTGCGCGAGCCTTCTTTGGGTCCGGTGTTCGGCGTGAAAGGCGGCGCGGCAGGCGGCGGCTATGCCCAAG
TTTTGCCGATGGAAGACATCAACCTGCACTTCACCGGAGATTTTCACGCCATCGGTGCGGCAAATAATCT
GCTTGCCGCGATGCTCGACAACCATATCTACCAAGGCAACGAGTTGAACATCGACCCCAAACGCGTGCTG
TGGCGGCGCGTGGTCGATATGAACGACCGCCAGTTGCGCAACATCATCGACGGCATGGGCAAGCCTGTTG
ACGGCGTGATGCGTCCTGACGGTTTCGATATTACCGTTGCTTCCGAAGTGATGGCGGTATTCTGTCTTGC
CAAAGACATCAGCGATTTGAAAGAGCGTTTGGGCAACATCCTTGTCGCCTACGCCAAAGACGGCAGCCCC
GTTTACGCCAAAGATTTGAAAGCGAATGGCGCGATGGCGGCATTGCTTAAAGATGCGATTAAGCCCAACT
TGGTGCAAACCATCGAAGGCACGCCCGCCTTCGTACACGGCGGCCCGTTCGCCAACATCGCCCACGGCTG
CAACTCCGTAACCGCAACCCGTCTGGCGAAACACCTTGCCGATTACGCCGTAACCGAAGCAGGCTTCGGC
GCGGACTTGGGCGCGGAAAAATTCTGCGACATCAAATGCCGCCTTGCCGGTTTGAAACCTGATGCGGCTG
TTGTCGTGGCGACTGTCCGCGCGTTGAAATATAACGGCGGCGTGGAACGCGCCAACCTCGGCGAAGAAAA
TTTAGACGCTTTGGAAAAAGGTTTGCCCAACCTGCTGAAACACATTTCCAACCTGAAAAACGTATTCGGA
CTGCCCGTCGTCGTTGCGCTCAACCGCTTCGTGTCCGACTCCGATGCCGAGTTGGCGATGATTGAAAAAG
CCTGTGCCGAACACGGCGTTGAAGTTTCCCTGACCGAAGTGTGGGGCAAAGGTGGTGCGGGCGGCGCGGA
TTTGGCGCGCAAAGTCGTCAACGCCATTGAAAGTCAAACCAATAACTTCGGTTTCGCCTACGATGTCGAG
TTGGGCATCAAAGACAAAATCCGTGCGATTGCCCAAAAAGTGTACGGCGCGGAAGATGTTGATTTCAGCG
CGGAAGCGTCTGCCGAAATCGCTTCACTGGAAAAACTGGGCTTGGACAAAATGCCGATCTGCATGGCGAA
AACCCAATACTCTTTGAGCGACAACGCCAAACTGTTGGGCTGCCCCGAAGACTTCCGCATCGCCGTGCGC
GGCATCACCGTTTCCGCAGGCGCAGGTTTCATCGTCGCCCTGTGCGGCAACATGATGAAAATGCCCGGCC
TGCCCAAAGTTCCGGCTGCCGAGAAAATCGATGTGGACGCAGAAGGCGTGATTCACGGCTTGTTCTG
Protein Sequence 
>gi|218767577|ref|YP_002342089.1| formate--tetrahydrofolate ligase [Neisseria meningitidis Z2491] MSFKTDAEIAQSSTMRPIGEIAAKLGLNVDNIEPYGHYKAKINPAEAFKLPQKQGRLILVTAINPTPAGEGKTTVTIGLADALRHIGKDSVIALREPSLGPVFGVKGGAAGGGYAQVLPMEDINLHFTGDFHAIGAANNLLAAMLDNHIYQGNELNIDPKRVLWRRVVDMNDRQLRNIIDGMGKPVDGVMRPDGFDITVASEVMAVFCLAKDISDLKERLGNILVAYAKDGSPVYAKDLKANGAMAALLKDAIKPNLVQTIEGTPAFVHGGPFANIAHGCNSVTATRLAKHLADYAVTEAGFGADLGAEKFCDIKCRLAGLKPDAAVVVATVRALKYNGGVERANLGEENLDALEKGLPNLLKHISNLKNVFGLPVVVALNRFVSDSDAELAMIEKACAEHGVEVSLTEVWGKGGAGGADLARKVVNAIESQTNNFGFAYDVELGIKDKIRAIAQKVYGAEDVDFSAEASAEIASLEKLGLDKMPICMAKTQYSLSDNAKLLGCPEDFRIAVRGITVSAGAGFIVALCGNMMKMPGLPKVPAAEKIDVDAEGVIHGLF
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: fhs mutant is attenuated in rats (Sun et al., 2000)
References
Sun et al., 2000: Sun YH, Bakshi S, Chalmers R, Tang CM. Functional genomics of Neisseria meningitidis pathogenesis. Nature medicine. 2000; 6(11); 1269-1273. [PubMed: 11062540].