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drrA

Victor ID 294
Gene Name drrA
Sequence Strain (Species/Organism) Mycobacterium tuberculosis H37Rv
NCBI Gene ID 888168
NCBI Protein GI 15610073
Locus Tag Rv2936
Protein Accession NP_217452.1
Other Database IDs UniProtKB-ID: DRRA_MYCTU
UniRef100: UniRef100_P96205
UniRef90: UniRef90_P96205
UniRef50: UniRef50_P96205
UniParc: UPI0000036B97
EMBL: AE000516
EMBL: BX842581
EMBL-CDS: AAK47333.1
EMBL-CDS: CAB06095.1
RefSeq_NT: NC_000962.2
RefSeq_NT: NC_002755.2
EnsemblGenome: EBMYCG00000001696
EnsemblGenome_TRS: EBMYCT00000001697
EnsemblGenome_PRO: EBMYCP00000001697
EnsemblGenome: EBMYCG00000070926
EnsemblGenome_TRS: EBMYCT00000070931
EnsemblGenome_PRO: EBMYCP00000068990
GenomeReviews: AE000516_GR
GenomeReviews
Taxonomy ID 83332
Gene Starting Position 3272213
Gene Ending Position 3273208
Gene Strand (Orientation) +
Protein Name PROBABLE DAUNORUBICIN-DIM-TRANSPORT ATP-BINDING PROTEIN ABC TRANSPORTER DRRA
DNA Sequence 
>gi|57116681:3272213-3273208 Mycobacterium tuberculosis H37Rv, complete genome
GATGCGCAACGACGACATGGCGGTGGTGGTTAACGGGGTTCGCAAGACCTACGGCAAGGGCAAGATTGTG
GCCCTCGATGACGTGAGTTTCAAGGTGCGCCGCGGTGAAGTGATCGGGCTGCTGGGCCCCAACGGGGCCG
GCAAGACGACCATGGTGGACATCTTGTCGACGCTGACCCGACCGGATGCCGGCTCGGCGATCATCGCTGG
CTACGATGTTGTTTCCGAACCGGCCGGTGTACGCCGCTCGATCATGGTCACCGGGCAGCAGGTGGCCGTC
GACGACGCGCTTTCCGGTGAGCAGAACCTGGTGTTGTTTGGTCGTCTGTGGGGACTGAGCAAGTCCGCGG
CGCGCAAACGCGCCGCCGAACTGCTCGAGCAATTCAGCCTCGTACATGCCGGAAAGAGGCGGGTGGGCAC
CTACTCCGGCGGAATGCGCCGACGAATAGACATCGCGTGCGGATTGGTGGTCCAACCCCAGGTGGCGTTC
TTAGACGAGCCCACCACCGGGCTCGATCCCAGGAGCCGGCAAGCTATTTGGGATCTGGTGGCCAGCTTCA
AGAAGCTGGGCATTGCCACGTTGTTGACCACGCAGTATCTCGAGGAGGCGGATGCGCTCAGTGACCGCAT
CATCCTGATCGATCACGGCATAATCATCGCCGAAGGCACCGCGAATGAACTCAAGCACCGCGCCGGCGAC
ACCTTCTGCGAAATAGTGCCCCGCGATCTGAAGGATCTGGACGCTATCGTCGCGGCGCTCGGTTCGCTGT
TGCCCGAGCACCACAGGGCGATGCTGACGCCCGACTCAGACCGCATTACGATGCCGGCGCCTGACGGCAT
ACGTATGCTCGTCGAGGCAGCGCGCCGGATCGACGAGGCGAGGATCGAGCTAGCCGATATTGCGCTGCGC
CGACCGTCACTCGATCACGTATTCCTGGCCATGACGACCGATCCCACCGAGTCTCTGACCCATCTGGTGT
CGGGGTCCGCGCGATG
Protein Sequence 
>gi|15610073|ref|NP_217452.1| daunorubicin ABC transporter ATP-binding protein DrrA [Mycobacterium tuberculosis H37Rv] MRNDDMAVVVNGVRKTYGKGKIVALDDVSFKVRRGEVIGLLGPNGAGKTTMVDILSTLTRPDAGSAIIAGYDVVSEPAGVRRSIMVTGQQVAVDDALSGEQNLVLFGRLWGLSKSAARKRAAELLEQFSLVHAGKRRVGTYSGGMRRRIDIACGLVVQPQVAFLDEPTTGLDPRSRQAIWDLVASFKKLGIATLLTTQYLEEADALSDRIILIDHGIIIAEGTANELKHRAGDTFCEIVPRDLKDLDAIVAALGSLLPEHHRAMLTPDSDRITMPAPDGIRMLVEAARRIDEARIELADIALRRPSLDHVFLAMTTDPTESLTHLVSGSAR
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: attenuated in mice (Sassetti and Rubin, 2003).
COG COG1131V, under V: Defense mechanisms
References
Sassetti and Rubin, 2003: Sassetti CM, Rubin EJ. Genetic requirements for mycobacterial survival during infection. Proceedings of the National Academy of Sciences of the United States of America. 2003; 100(22); 12989-12994. [PubMed: 14569030].