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nadA from Neisseria meningitidis FAM18

Victor ID 2937
Gene Name nadA from Neisseria meningitidis FAM18
Sequence Strain (Species/Organism) Neisseria meningitidis FAM18
NCBI Gene ID 4676346
NCBI Protein GI 121635470
Locus Tag NMC1772
Protein Accession YP_975715.1
Other Database IDs UniProtKB-ID: NADA_NEIMF
UniRef100: UniRef100_A1KVN9
UniRef90: UniRef90_Q5F6I7
UniRef50: UniRef50_B2UAP5
UniParc: UPI0000ECFA17
EMBL: AM421808
EMBL-CDS: CAM10943.1
RefSeq_NT: NC_008767.1
EnsemblGenome: EBNEIG00000007749
EnsemblGenome_TRS: EBNEIT00000007749
EnsemblGenome_PRO: EBNEIP00000007518
GenomeReviews: AM421808_GR
KEGG: nmc:NMC1772
NMPDR: fig|487.2.peg.86
eggNOG: COG0379
HOGENOM: HBG291157
OMA: IAHPECE
ProtClustDB: PRK09375
BioCyc: NMEN272831:NMC1772-MONOMER
Taxonomy ID 272831
Gene Starting Position 1809568
Gene Ending Position 1810680
Gene Strand (Orientation) +
Protein Name quinolinate synthetase
DNA Sequence 
>gi|121633901:1809568-1810680 Neisseria meningitidis FAM18, complete genome
CATGCAAACCGCCGCCCGCCGCTCGTTCGATTACGATATGCCCCTCATTCAAACGCCGACTTCCGCCTGC
CAAATCCGTCAGGCGTGGGCGAAGGTTGCCGACACGCCCGACCGCGAAACGGCAGGCCGTCTGAAAGACG
AAATCAAGGCTTTGCTGAAGGAGAAAAACGCGGTCTTGGTGGCGCATTATTATGTTGATCCGCTGATTCA
GGATTTGGCTTTGGAAACGGGCGGATGCGTGGGCGATTCGCTGGAAATGGCGCGCTTTGGTGCGGAACAC
GAAGCCGATACATTAGTGGTGGCGGGCGTGCGTTTCATGGGCGAGAGCGCGAAAATCCTCTGCCCTGAAA
AAACAGTGCTGATGCCTGATTTGGAGGCGGAATGTTCTTTGGATTTGGGTTGCCCGGAAGAGGCGTTTTC
GGCGTTTTGCGACCAACACCCCGACCGCACGGTGGTGGTGTACGCCAACACTTCCGCCGCCGTGAAAGCG
CGTGCCGACTGGGTGGTAACGTCTTCAGTGGCGTTGGAAATCGTGTCGTATCTGAAATCGCGCGGCGAGA
AGCTGATTTGGGGACCCGACCGCCACCTCGGCGACTACATCTGCCGCGAAACGGGCGCGGATATGCTGTT
GTGGCAGGGTTCGTGCATCGTCCACAACGAATTTAAAGGGCAGGAGCTGGCGGCGTTGAAAGCGGAACAT
CCCGACGCGGTGGTGCTGGTTCATCCTGAATCGCCGCAAAGCGTCATCGAACTGGGCGACGTGGTCGGCT
CGACCAGCAAACTGCTCAAGGCCGCCGTATCGCGTCCTGAAAAAAAATTCATCGTGGCGACCGATTTGGG
CATCCTGCACGAAATGCAAAAGCAGGCGCCCGACAAAGAATTTATCGCCGCGCCGACGGCGGGCAACGGT
GGAAGCTGTAAAAGCTGCGCGTTCTGCCCGTGGATGGCGATGAATTCGCTGGGCGGCATCAAATACGCCC
TGACAAGCGGACGTAACGAAATCCTGTTGGACAGGAAGCTGGGCGAAGCCGCCAAACTGCCTTTGCAGCG
TATGCTCGACTTCGCGGCAGGACTCAAACGCGGGGATGTGTTCAACGGCATGGGTCCCGCCTG
Protein Sequence 
>gi|121635470|ref|YP_975715.1| quinolinate synthetase [Neisseria meningitidis FAM18] MQTAARRSFDYDMPLIQTPTSACQIRQAWAKVADTPDRETAGRLKDEIKALLKEKNAVLVAHYYVDPLIQDLALETGGCVGDSLEMARFGAEHEADTLVVAGVRFMGESAKILCPEKTVLMPDLEAECSLDLGCPEEAFSAFCDQHPDRTVVVYANTSAAVKARADWVVTSSVALEIVSYLKSRGEKLIWGPDRHLGDYICRETGADMLLWQGSCIVHNEFKGQELAALKAEHPDAVVLVHPESPQSVIELGDVVGSTSKLLKAAVSRPEKKFIVATDLGILHEMQKQAPDKEFIAAPTAGNGGSCKSCAFCPWMAMNSLGGIKYALTSGRNEILLDRKLGEAAKLPLQRMLDFAAGLKRGDVFNGMGPA
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: NadA mutation decreases epithelial adhesion of capsulate N. meningitidis and invasion by acapsulate N. meningitidis (Carbonnelle et al., 2009).
COG COG0379H, under H: Coenzyme transport and metabolism
References
Carbonnelle et al., 2009: Carbonnelle E, Hill DJ, Morand P, Griffiths NJ, Bourdoulous S, Murillo I, Nassif X, Virji M. Meningococcal interactions with the host. Vaccine. 2009; 27 Suppl 2; B78-89. [PubMed: 19481311].