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ilvD from Neisseria meningitidis FAM18

Victor ID 2932
Gene Name ilvD from Neisseria meningitidis FAM18
Sequence Strain (Species/Organism) Neisseria meningitidis FAM18
NCBI Gene ID 4675932
NCBI Protein GI 121634888
Locus Tag NMC1090
Protein Accession YP_975133.1
Other Database IDs UniProtKB-ID: ILVD_NEIMF
UniRef100: UniRef100_A1KU04
UniRef90: UniRef90_Q5F8G6
UniRef50: UniRef50_Q5F8G6
UniParc: UPI0000ECF87C
EMBL: AM421808
EMBL-CDS: CAM10345.1
RefSeq_NT: NC_008767.1
EnsemblGenome: EBNEIG00000008287
EnsemblGenome_TRS: EBNEIT00000008287
EnsemblGenome_PRO: EBNEIP00000008056
GenomeReviews: AM421808_GR
KEGG: nmc:NMC1090
NMPDR: fig|487.2.peg.2213
eggNOG: COG0129
HOGENOM: HBG671001
OMA: KVPCLSK
ProtClustDB: PRK12448
BioCyc: NMEN272831:NMC1090-MONOMER
Taxonomy ID 272831
Gene Starting Position 1067747
Gene Ending Position 1069606
Gene Strand (Orientation) -
Protein Name dihydroxy-acid dehydratase
DNA Sequence 
>gi|121633901:1067747-1069606 Neisseria meningitidis FAM18, complete genome
CTTATCTTTCGATTTGCGCTACGTCGCGCACCGCGCCTTTGTCGGCGGAAGTCGCCATCGCGCCGTAAGC
ACGCAGGGCTGCGGAGACGTAGCGGTCGCGGTTTTCCGGTTTCCACGCTTTGCTGCCGCGCGCTTCCATT
TCGGCACGGCGGGCGGCAAGCTCTTCATCGGAAATGGCAAGGTGGATGCTGCGGTTGGGGATGTCGATTT
CGACGGTATCGCCTTCGTGTACCAAACCGATCGCGCCACCTTCCGCCGCTTCGGGCGAGGCGTGTCCGAT
GGACAAACCTGATGTGCCGCCGGAGAAGCGTCCGTCGGTTAAGAGAGCGCAGGCTTTGCCGAGGCCTTTA
GATTTCAGGTAGGAAGTCGGATACAGCATTTCCTGCATGCCCGGGCCGCCTTTCGGGCCTTCGTAGCGGA
TGATGACGATGTCGCCGGCGACGATTTGGTTGCCCAAAATGCCTTCTACTGCGTCTTCTTGGCTTTCAAA
CACGCGGGCGCGGCCGGTGAATTTGAGGATGCTCTCGTCCACGCCTGCGGTTTTTACCACGCAGCCGCGC
TCGGCGATGTTGCCGAACAAGACCGCCAAACCGCCGTCTTGCGAGTAGGCGTGTGCCACGTCGCGGATAC
AGCCTTTTTCGCGGTCGAGGTCGAGGGTTTTCCACATACGGTTTTGCGAGAACGCTTGGGTGGTGCGTAC
GCCGCCGGGCGCGGCTTTGAAGCGTTCGATGGCGCGGGTGTTTTCAGGGTTGGTTATGTCCCATTTTTCA
ATCGCGTCTTTCAGCGTCGGTGCGTGGATAGTGTGCACGTCGGTGTGCAGCTTGCCCGCTTTGTCCAATT
CTTTCAGGATGGCGAAAATGCCGCCGGCGCGGTGCACGTCTTCCATATAGTAGTCGTGGTTGTTGGGTGC
GGTTTTGCAGATGCAGGGCACAACGCGGCTTAAGCGGTCAATGTCGGCCATTTTGAAATCGACACCGGCT
TCGTTGGCAACGGCCAACAGGTGCAAAATGGTATTGGTGCTGCCGCCCATCGCAATATCCATCGTCATAG
CGTTTTCAAACGCTTTTTTGGTGGCAATGCTGCGCGGTAACACGGTTTCATCGTTTTGCTCGTAATAGCG
TTTGGTGATTTCGACAATCATACGGCCGGCTTCGAGGAACAGTTCTTTGCGGCCGACGTGGGTCGCCAAA
TACGAACCGTTGCCGGGTAGGGACAGACCGAGTGCTTCGGTCAGGCAGTTCATCGAGTTTGCCGTAAACA
TACCCGAACACGAGCCGCAGGTCGGGCAGGCGTTTTGTTCGACTTCCTCGACTTGCCGGTTGCTGACATT
GTCGTCCGCCGATTCAATCATCGCGTCAATCAAGTCCAAACGGCGTTCGGGCTGGATGTTTGCCACGCCG
ATAACTTTACCTGCTTCCATCGGACCGCCGGAAACGAAGATGGTCGGGATGTTCAGGCGCATCGCGGCAA
TCAGCATGCCCGGGGTGATTTTGTCGCAGTTGGAAATGCACACCAGCGCGTCGGCGCAGTGGGCATTGAC
CATATATTCGATGGAGTCGGCAATCAAATCGCGGCTGGGCAGGGAATACAGCATACCGCTGTGTCCCATA
GCGATGCCGTCGTCGATGGCGATGGTGTTGAATTCTTTGGCGATGGCGCCCGCCTTTTCGATTTCGCGGG
CAACCAGCTGGCCCATATTGTGCAGGTGGACATGGCCGGGCACGAATTGGGTGAAGGAGTTGGCAACGGC
GATGATGGGCTTGCCGAAGTCGGTTTCCATCACGCCGGTGGCGCGCCACAATGCACGTGCGCCCGCCATA
TTGCGGCCGTGGGTGGAGGTTTTGGAGCGGTATTCTGGCA
Protein Sequence 
>gi|121634888|ref|YP_975133.1| dihydroxy-acid dehydratase [Neisseria meningitidis FAM18] MPEYRSKTSTHGRNMAGARALWRATGVMETDFGKPIIAVANSFTQFVPGHVHLHNMGQLVAREIEKAGAIAKEFNTIAIDDGIAMGHSGMLYSLPSRDLIADSIEYMVNAHCADALVCISNCDKITPGMLIAAMRLNIPTIFVSGGPMEAGKVIGVANIQPERRLDLIDAMIESADDNVSNRQVEEVEQNACPTCGSCSGMFTANSMNCLTEALGLSLPGNGSYLATHVGRKELFLEAGRMIVEITKRYYEQNDETVLPRSIATKKAFENAMTMDIAMGGSTNTILHLLAVANEAGVDFKMADIDRLSRVVPCICKTAPNNHDYYMEDVHRAGGIFAILKELDKAGKLHTDVHTIHAPTLKDAIEKWDITNPENTRAIERFKAAPGGVRTTQAFSQNRMWKTLDLDREKGCIRDVAHAYSQDGGLAVLFGNIAERGCVVKTAGVDESILKFTGRARVFESQEDAVEGILGNQIVAGDIVIIRYEGPKGGPGMQEMLYPTSYLKSKGLGKACALLTDGRFSGGTSGLSIGHASPEAAEGGAIGLVHEGDTVEIDIPNRSIHLAISDEELAARRAEMEARGSKAWKPENRDRYVSAALRAYGAMATSADKGAVRDVAQIER
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: ilvD mutant is attenuated in rats (Sun et al., 2000).
COG COG0129EG, under E: Amino acid transport and metabolism; G: Carbohydrate transport and metabolism
References
Sun et al., 2000: Sun YH, Bakshi S, Chalmers R, Tang CM. Functional genomics of Neisseria meningitidis pathogenesis. Nature medicine. 2000; 6(11); 1269-1273. [PubMed: 11062540].