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tonB from Neisseria meningitidis FAM18

Victor ID 2931
Gene Name tonB from Neisseria meningitidis FAM18
Sequence Strain (Species/Organism) Neisseria meningitidis FAM18
NCBI Gene ID 4675898
NCBI Protein GI 121635364
Locus Tag NMC1650
Protein Accession YP_975609.1
Other Database IDs UniProtKB-ID: A1KVD3_NEIMF
UniRef100: UniRef100_A1KVD3
UniRef90: UniRef90_O06432
UniRef50: UniRef50_O06432
UniParc: UPI0000ECF975
EMBL: AM421808
EMBL-CDS: CAM10835.1
RefSeq_NT: NC_008767.1
EnsemblGenome: EBNEIG00000006970.
EnsemblGenome_TRS: EBNEIT00000006970
EnsemblGenome_PRO: EBNEIP00000006739
GenomeReviews: AM421808_GR
KEGG: nmc:NMC1650
NMPDR: fig|487.2.peg.1953
eggNOG: COG0810
HOGENOM: HBG134785
OMA: NEINAYK
ProtClustDB: CLSK878208
BioCyc: NMEN272831:NMC1650-MONOMER
Taxonomy ID 272831
Gene Starting Position 1684417
Gene Ending Position 1685253
Gene Strand (Orientation) -
Protein Name TonB protein
DNA Sequence 
>gi|121633901:1684417-1685253 Neisseria meningitidis FAM18, complete genome
CCTAATTCAATTCAAACTTGACGGGGACTTTAAACTCCGTCCAGGCATTGGCTTGAAAATGCCCGTTTTG
CGCCGCCTTGCGTGCCGCATTGTCCAACCGAGAAAAACCACTGCTTTTCACGATTTTAACGGACTCGACA
TGACCGCCCGGAGAAACCAAAACGCTCAAAACAACCGTACCCTGCTCGTCATTCTCCATAGAAAGCGTGG
GATAAGCCGGGCGCGGAATGCTGCCGTTGGCGCGTAAAGGATTGCCTTTGCTGCTGCCGGCTCCTTCCCC
GTGTTCGCCTTTGACACCGCCGCTACCTTTACCGCTGCCTTCTCCGCGCCCCGTTCCGTCTCCTTTGGTA
CCGGTTTCTTCCCCATTACCCTGCTCGCTGTCTGCTTTGGCAGAAGCATTGCTGGGATGTTCGGCAGGTT
TTTCAGACGGCTTCTCGACCGGTTTTTCCGCCGGTTTCGGGACAGGCTTCGCTTCCGGCTTAGGCTCTGG
TTTCGGTTTTTCTTCGGGTTTCGGCTTTTCTTCAGGTTTCGGCTCTTCCTTAGGCTGCTGAATATCCGCA
TCCGCCTTTTTCGTAACCACCGGCTTCAAAACCGGCTTGGGCGGCTCGACAGGTTTGGGCGGCTCAGGCT
CAGGTTGCGGCTCAGGCGCAGCAGGCGCACCTGCGCCTTCGGGTGCACCGTCCCCTCCGCCAAAATCACC
CAAATCGACAAATTCGATAACATTTCCTGACTCTATCACGGGCAGCTTGTGCGCCTGCCAGAGCAATGCC
ACCATTGCCAAATGCAGCAGTGCGACGGAAAACACGACTGCGGGGGTTAAAATTCGTTCTTTATCCA
Protein Sequence 
>gi|121635364|ref|YP_975609.1| TonB protein [Neisseria meningitidis FAM18] MDKERILTPAVVFSVALLHLAMVALLWQAHKLPVIESGNVIEFVDLGDFGGGDGAPEGAGAPAAPEPQPEPEPPKPVEPPKPVLKPVVTKKADADIQQPKEEPKPEEKPKPEEKPKPEPKPEAKPVPKPAEKPVEKPSEKPAEHPSNASAKADSEQGNGEETGTKGDGTGRGEGSGKGSGGVKGEHGEGAGSSKGNPLRANGSIPRPAYPTLSMENDEQGTVVLSVLVSPGGHVESVKIVKSSGFSRLDNAARKAAQNGHFQANAWTEFKVPVKFELN
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: tonB mutant is unable to replicate within human epithelial cells (Larson et al., 2002).
COG COG0810M, under M: Cell wall/membrane/envelope biogenesis
References
Larson et al., 2002: Larson JA, Higashi DL, Stojiljkovic I, So M. Replication of Neisseria meningitidis within epithelial cells requires TonB-dependent acquisition of host cell iron. Infection and immunity. 2002; 70(3); 1461-1467. [PubMed: 11854233].