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metF from Neisseria meningitidis FAM18

Victor ID 2925
Gene Name metF from Neisseria meningitidis FAM18
Sequence Strain (Species/Organism) Neisseria meningitidis FAM18
NCBI Gene ID 4675430
NCBI Protein GI 121634746
Locus Tag NMC0921
Protein Accession YP_974991.1
Other Database IDs UniProtKB-ID: A1KTL2_NEIMF
UniRef100: UniRef100_A1KTL2
UniRef90: UniRef90_Q9JZQ3
UniRef50: UniRef50_Q89B13
UniParc: UPI00000445F7
EMBL: AM421808
EMBL-CDS: CAM10198.1
RefSeq_NT: NC_008767.1
EnsemblGenome: EBNEIG00000008405.
EnsemblGenome_TRS: EBNEIT00000008405
EnsemblGenome_PRO: EBNEIP00000008174
GenomeReviews: AM421808_GR
KEGG: nmc:NMC0921
eggNOG: COG0685
HOGENOM: HBG649727
OMA: FFPPKTP
ProtClustDB: PRK09432
BioCyc: NMEN272831:NMC0921-MONOMER
Taxonomy ID 272831
Gene Starting Position 918260
Gene Ending Position 919138
Gene Strand (Orientation) +
Protein Name 5,10-methylenetetrahydrofolate reductase
DNA Sequence 
>gi|121633901:918260-919138 Neisseria meningitidis FAM18, complete genome
CATGAATTACGCAAAAGAAATCAATGCGTTAAATAACAGCCTTTCCGATTTGAAAGGCGACATCAACGTT
TCATTCGAATTTTTCCCGCCGAAAAACGAACAAATGGAAACCATGCTGTGGGATTCCATCCATCGCCTGC
AAACCTTGCACCCGAAATTTGTTTCCGTAACTTACGGTGCAAACTCAGGCGAGCGCGACCGCACACACGG
CATCGTCAAACGCATCAAACAGGAAACCGGCTTGGAAGCCGCCCCGCACCTGACCGGTATTGACGCTTCT
CCCGACGAATTGCGCCAAATCGCCAAAGACTATTGGGACAGCGGCATCCGCCGCATTGTCGCCCTGCGCG
GCGACGAGCCGCCCGGCTACGAGAAAAAACCTTTCTATGCCGAAGATTTGGTCAAACTGTTGCGCTCCGT
TGCCGACTTCGACATTTCCGTAGCGGCCTATCCTGAGGTACACCCGGAAGCCAAATCCGCTCAAGCCGAC
TTGATCAATCTGAAACGCAAAATCGATGCGGGCGCGAACCACGTCATCACCCAATTCTTCTTCGATGTGG
AACGCTACCTGCGCTTCCGCGACCGCTGCGTGATGTTGGGTATCGATGTGGAAATCGTCCCCGGTATTTT
GCCTGTTACCAACTTCAAGCAGCTCGGCAAAATGGCGCAAGTAACCAACGTCAAAATCCCAAGCTGGCTG
TCGCAAATGTATGAAGGTTTGGACGACGACCAAGGTACGCGCAATCTGGTGGCGGCAAGTATCGCCATCG
ATATGGTCAAAGTCCTGTCCCGCGAAGGCGTGAAAGATTTCCACTTCTATACGCTTAACCGCAGCGAGCT
GACTTACGCCATCTGCCATATTTTAGGCGTGCGCCCTTA
Protein Sequence 
>gi|121634746|ref|YP_974991.1| 5,10-methylenetetrahydrofolate reductase [Neisseria meningitidis FAM18] MNYAKEINALNNSLSDLKGDINVSFEFFPPKNEQMETMLWDSIHRLQTLHPKFVSVTYGANSGERDRTHGIVKRIKQETGLEAAPHLTGIDASPDELRQIAKDYWDSGIRRIVALRGDEPPGYEKKPFYAEDLVKLLRSVADFDISVAAYPEVHPEAKSAQADLINLKRKIDAGANHVITQFFFDVERYLRFRDRCVMLGIDVEIVPGILPVTNFKQLGKMAQVTNVKIPSWLSQMYEGLDDDQGTRNLVAASIAIDMVKVLSREGVKDFHFYTLNRSELTYAICHILGVRP
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: metF mutant is attenuated in rats (Sun et al., 2000).
COG COG0685E, under E: Amino acid transport and metabolism
References
Sun et al., 2000: Sun YH, Bakshi S, Chalmers R, Tang CM. Functional genomics of Neisseria meningitidis pathogenesis. Nature medicine. 2000; 6(11); 1269-1273. [PubMed: 11062540].