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gdhA from Neisseria meningitidis FAM18

Victor ID 2924
Gene Name gdhA from Neisseria meningitidis FAM18
Sequence Strain (Species/Organism) Neisseria meningitidis FAM18
NCBI Gene ID 4675196
NCBI Protein GI 121635346
Locus Tag NMC1625
Protein Accession YP_975591.1
Other Database IDs UniProtKB-ID: A1KVB4_NEIMF
UniRef100: UniRef100_A1KVB4
UniRef90: UniRef90_A1KVB4
UniRef50: UniRef50_Q9ZKD8
UniParc: UPI0000ECF67C
EMBL: AM421808
EMBL-CDS: CAM10815.1
RefSeq_NT: NC_008767.1
EnsemblGenome: EBNEIG00000007674.
EnsemblGenome_TRS: EBNEIT00000007674
EnsemblGenome_PRO: EBNEIP00000007443
GenomeReviews: AM421808_GR
KEGG: nmc:NMC1625
NMPDR: fig|487.2.peg.1930
eggNOG: COG0334
HOGENOM: HBG590661
OMA: EMAQNAS
ProtClustDB: PRK09414
BioCyc: NMEN272831:NMC1625-MONOMER
Taxonomy ID 272831
Gene Starting Position 1657743
Gene Ending Position 1659077
Gene Strand (Orientation) +
Protein Name glutamate dehydrogenase
DNA Sequence 
>gi|121633901:1657743-1659077 Neisseria meningitidis FAM18, complete genome
AATGACTGACCTGAACACCCTGTTTGCCAACCTCAAACAACGCAATCCCAATCAGGAGCCGTTCCATCAG
GCGGTTGAAGAAGTCTTCATGAGTCTCGATCCGTTTTTGGCAAAAAATCCGAAATACACCCAGCAAAGCC
TGCTGGAACGCATCGTCGAACCCGAACGCGTCGTCATGTTCCGCGTAACCTGGCAGGACGATAAAGGGCA
AGTCCAAGTCAACCGGGGCTACCGCGTGCAAATGAGTTCCGCCATCGGTCCTTACAAAGGCGGCCTGCGC
TTCCATCCGACCGTCGATTTGGGCGTATTGAAATTCCTCGCTTTTGAACAAGTGTTCAAAAACGCCTTGA
CCACCCTGCCTATGGGCGGCGGCAAAGGCGGTTCCGACTTCGACCCCAAAGGCAAATCCGATGCCGAAGT
AATGCGCTTCTGCCAAGCCTTTATGACCGAACTCTACCGCCACATCGGCGCGGACACCGACGTTCCGGCC
GGCGACATCGGCGTAGGCGGACGCGAAATCGGCTATCTGTTCGGACAATACAAAAAAATCCGCAACGAGT
TTTCTTCCGTCCTGACCGGCAAAGGTTTGGAATGGGGCGGCAGCCTCATCCGTCCCGAAGCGACCGGCTA
CGGCTGCGTCTATTTCGCCCAAGCGATGCTGCAAACCCGCAACGATAGTTTTGAAGGCAAACGCGTCCTG
ATTTCCGGTTCCGGCAACGTGGCGCAATACGCCGCCGAAAAAGCCATCCAACTGGGCGCGAAAGTGCTGA
CCGTTTCCGACTCCAACGGCTTCGTCCTCTTCCCCGACAGCGGTATGACCGAAGCGCAACTCGCCGCCTT
GATCGAATTGAAAGAAGTCCGCCGCGAACGCGTTGCCACCTACGCCAAAGAGCAAGGTCTGCAATACTTT
GAAAACCAAAAACCGTGGGGCGTCGCCGCCGAAATCGCCCTGCCCTGCGCGACCCAGAACGAATTGGACG
AAGAAGCCGCCAAAACCCTGTTGGCAAACGGCTGCTACGTCGTTGCCGAAGGTGCGAATATGCCGTCGAC
TTTGGGCGCGGTCGAGCAATTTATCAAAGCCGGCATCCTCTACGCCCCGGGAAAAGCCTCCAATGCCGGC
GGCGTAGCAACTTCAGGTTTGGAAATGAGCCAAAACGCCATCCGCCTGTCTTGGACTCGTGAAGAAGTCG
ACCAACGCCTGTTCGGCATCATGCAAAGCATCCACGAATCCTGTCTGAAATACGGCAAAGTCGGCGACAC
AGTAAACTACGTCAATGGTGCGAACATTGCCGGTTTCGTCAAAGTTGCCGATGCGATGCTGGCGCAAGGC
TTCTA
Protein Sequence 
>gi|121635346|ref|YP_975591.1| glutamate dehydrogenase [Neisseria meningitidis FAM18] MTDLNTLFANLKQRNPNQEPFHQAVEEVFMSLDPFLAKNPKYTQQSLLERIVEPERVVMFRVTWQDDKGQVQVNRGYRVQMSSAIGPYKGGLRFHPTVDLGVLKFLAFEQVFKNALTTLPMGGGKGGSDFDPKGKSDAEVMRFCQAFMTELYRHIGADTDVPAGDIGVGGREIGYLFGQYKKIRNEFSSVLTGKGLEWGGSLIRPEATGYGCVYFAQAMLQTRNDSFEGKRVLISGSGNVAQYAAEKAIQLGAKVLTVSDSNGFVLFPDSGMTEAQLAALIELKEVRRERVATYAKEQGLQYFENQKPWGVAAEIALPCATQNELDEEAAKTLLANGCYVVAEGANMPSTLGAVEQFIKAGILYAPGKASNAGGVATSGLEMSQNAIRLSWTREEVDQRLFGIMQSIHESCLKYGKVGDTVNYVNGANIAGFVKVADAMLAQGF
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: gdhA mutant is attenuated in rats (Sun et al., 2000).
COG COG0334E, under E: Amino acid transport and metabolism
References
Sun et al., 2000: Sun YH, Bakshi S, Chalmers R, Tang CM. Functional genomics of Neisseria meningitidis pathogenesis. Nature medicine. 2000; 6(11); 1269-1273. [PubMed: 11062540].