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rfaF from Neisseria meningitidis FAM18

Victor ID 2921
Gene Name rfaF from Neisseria meningitidis FAM18
Sequence Strain (Species/Organism) Neisseria meningitidis FAM18
NCBI Gene ID 4675030
NCBI Protein GI 121635198
Locus Tag NMC1456
Protein Accession YP_975443.1
Other Database IDs UniProtKB-ID: A1KUW4_NEIMF
UniRef100: UniRef100_A1KUW4
UniRef90: UniRef90_A1KUW4
UniRef50: UniRef50_Q0A4V5
UniParc: UPI0000044600
EMBL: AM421808
EMBL-CDS: CAM10663.1
RefSeq_NT: NC_008767.1
EnsemblGenome: EBNEIG00000007404.
EnsemblGenome_TRS: EBNEIT00000007404
EnsemblGenome_PRO: EBNEIP00000007173
GenomeReviews: AM421808_GR
KEGG: nmc:NMC1456
eggNOG: COG0859
HOGENOM: HBG527482
OMA: MWIGDFV
ProtClustDB: CLSK878107
BioCyc: NMEN272831:NMC1456-MONOMER
Taxonomy ID 272831
Gene Starting Position 1464376
Gene Ending Position 1465386
Gene Strand (Orientation) -
Protein Name ADP-heptose:LPS heptosyltransferase II
DNA Sequence 
>gi|121633901:1464376-1465386 Neisseria meningitidis FAM18, complete genome
ATCATACCGCCTCTTCAACCGCCTGCACAATCTTCTCGGGATACAGCCTGTTGAGGCAGTCGGTATGCCC
CAGCGGACATTCCCGCTTAAAACAGGGCGAACATTCCAAGTGCAGGCTGACGATTTTCGCCCTGTCGCTC
AAAGGCGGCGTATGCGTCGGGCTGGAAGAACCGTAAACCGCCACCACCTTCCTGCCCAATGCCGCCGCCA
AGTGCATCAGCCCGCTGTCGTTGCACACGACCGTGTCCGCCAACGACAGCAAATCCATTGCCTGCGACAA
ATCGGTCTTTCCGCATAAATTCACACACATACCGTCTGAAAGGCAGTTGATTTCCTCGGCAATTTCATCA
TCTTTTTGCGAACCGAACAGCCAAACCTGCCAACCCGCCGCCGAATAATGTTTGCCCAACTCGGCAAAAT
ACCTTGTCGGCCAACGCTTTGCCGGCCCGAATTCCGCACCCGGACAAAAAGCCAGAACAGGCTTTCCAAT
ATCCAAGCCAAAGGTTTCGACAGAAATTTCCCGCCGCCGTTCATCAATGGAAAACTCGGGGAATCCCGAA
TGCCCGTCAAAATCCTCCTGGCTCGGATGCGCGAGAGCCGTATATCTGTCCACCATCAAAGGCAGACGTT
CCTTATCCAGCCTGCGTATATCGTTCAACAGAAAATAACGGCTTTCACCGACATAACCCGTCCTTTTACC
GATACCTGTCGCCAGCGCGATGATTGCCGATTTCAAAGAACCGGGCAACACGATAACCTGATCGTATCCG
CGCCGCCCCAAATCCCTACCGACCCGCCAGCGGCGTTTCAACTCCAACGCACCGTGTCCGAACGGATTTT
CAAGAATCTCATTCACTTCCGGCATACGCTCAAACACCGCCATCGACCACTTCGGTGCGAACACATCAAT
CGTGCAACCGGGGTGAAGTTCCTTCAAACGGCGGAACAAGGGCTGGGTCATCACGCAGTCGCCTATCCAA
CTGGGAGAAATAATCAGGATTTTGATGGACA
Protein Sequence 
>gi|121635198|ref|YP_975443.1| ADP-heptose--LPS heptosyltransferase [Neisseria meningitidis FAM18] MSIKILIISPSWIGDCVMTQPLFRRLKELHPGCTIDVFAPKWSMAVFERMPEVNEILENPFGHGALELKRRWRVGRDLGRRGYDQVIVLPGSLKSAIIALATGIGKRTGYVGESRYFLLNDIRRLDKERLPLMVDRYTALAHPSQEDFDGHSGFPEFSIDERRREISVETFGLDIGKPVLAFCPGAEFGPAKRWPTRYFAELGKHYSAAGWQVWLFGSQKDDEIAEEINCLSDGMCVNLCGKTDLSQAMDLLSLADTVVCNDSGLMHLAAALGRKVVAVYGSSSPTHTPPLSDRAKIVSLHLECSPCFKRECPLGHTDCLNRLYPEKIVQAVEEAV
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: rfaF mutant is attenuated in rats (Sun et al., 2000).
COG COG0859M, under M: Cell wall/membrane/envelope biogenesis
References
Sun et al., 2000: Sun YH, Bakshi S, Chalmers R, Tang CM. Functional genomics of Neisseria meningitidis pathogenesis. Nature medicine. 2000; 6(11); 1269-1273. [PubMed: 11062540].