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aroB from Neisseria meningitidis FAM18

Victor ID 2919
Gene Name aroB from Neisseria meningitidis FAM18
Sequence Strain (Species/Organism) Neisseria meningitidis FAM18
NCBI Gene ID 4674848
NCBI Protein GI 121634271
Locus Tag NMC0406
Protein Accession YP_974516.1
Other Database IDs UniProtKB-ID: AROB_NEIMF
UniRef100: UniRef100_A1KS84
UniRef90: UniRef90_Q5FAD4
UniRef50: UniRef50_A5CX62
UniParc: UPI0000125F76
EMBL: AM421808
EMBL-CDS: CAM09714.1
RefSeq_NT: NC_008767.1
EnsemblGenome: EBNEIG00000008564
EnsemblGenome_TRS: EBNEIT00000008564
EnsemblGenome_PRO: EBNEIP00000008333
GenomeReviews: AM421808_GR
KEGG: nmc:NMC0406
eggNOG: COG0337
HOGENOM: HBG632303
OMA: CEIKAEV
ProtClustDB: PRK00002
BioCyc: NMEN272831:NMC0406-MONOMER
Taxonomy ID 272831
Gene Starting Position 424558
Gene Ending Position 425637
Gene Strand (Orientation) -
Protein Name 3-dehydroquinate synthase
DNA Sequence 
>gi|121633901:424558-425637 Neisseria meningitidis FAM18, complete genome
ATCAGAGATACGGTTGCAGGGTGCGGCGGAGGATGTCCGTGTCGGTAATTTCGGTGATGTTGGCTTCGCC
CAGCCGGTTCAGACCGATAAAGCGCATGATGCCGCCGCTGACTTTTTTATCGTGGCTCATGTGTTCCAGC
CATTTTTCAAAGGCAAACACGGGTGGCGCGGACGGCAGTCCGGCGGCTTCGAGCAGGGCGGCGAGCCGCG
CGGTATCTGCGGCGGAGGTTTTGCCCAGTTGTTCGGACAAACGCGCCGCCAACACGCAGCCGGCGGCGAT
GGCTTCTCCATGCAGCCAAGTGCCGTAACCCATCTCGGTTTCAATGGCGTGTCCGAAGGTGTGTCCGAGG
TTGAGCCATGCGCGTATGCCCTGTTCGGTTTCGTCTTGGGCGACGATGTCTGCCTTCATTTGGCAGCAGC
GGTACACGGCTTGGGCGAGTTTTTCCCGATCGAGCGTCATCAGTTCGGGCATATGCTGTTCCAGCCATTC
AAAAAAGCCGATGTCGCCGAGCGCGCCGTATTTGATGACTTCCGCCATACCGGCGGACAATTCGCGGGCG
GGCAGGGTGTGCAGCGTGTCCAAGTCGGCAAGCACCGCCTGCGGCTGGTAAAACGCGCCAATCATATTTT
TGCCGAGCGGGTGGTTGATGGCGGTTTTGCCGCCCACCGATGAGTCGACCTGACTCAACAGTGTGGTCGG
TATTTGAACGAACGGTGCGCCGCGCTGGTAGGTGGCAGCGGCAAAGCCGACCATGTCGCCGATCACGCCG
CCGCCCAGTGCGATTAATGTGGTTTTGCGTTCGGCGCGGTTTTGCATCAGCCCGTCAAAGATGAGGTTGA
GCGTCTGCCAGTTTTTGTGCGCCTCGCCGTCGGGCAGGATGATGCTGAAATGGGATACGCCTGCCGCATC
CAATGCCGTCTGAAGCGTGCCGAGGTAGAGCGGGGCGACGGTTTCGTTGGCGATGATGGCGGCGCGTTTG
CCCAAATGCGGTTTGAGCAGGCTTCCTGCCTGCGGCAGCAGTCCGTTGCCGATAAAGATGGGGTAGCTGT
GGGACGGGGTGTGTACGGTCAGTGTTTTCA
Protein Sequence 
>gi|121634271|ref|YP_974516.1| 3-dehydroquinate synthase [Neisseria meningitidis FAM18] MKTLTVHTPSHSYPIFIGNGLLPQAGSLLKPHLGKRAAIIANETVAPLYLGTLQTALDAAGVSHFSIILPDGEAHKNWQTLNLIFDGLMQNRAERKTTLIALGGGVIGDMVGFAAATYQRGAPFVQIPTTLLSQVDSSVGGKTAINHPLGKNMIGAFYQPQAVLADLDTLHTLPARELSAGMAEVIKYGALGDIGFFEWLEQHMPELMTLDREKLAQAVYRCCQMKADIVAQDETEQGIRAWLNLGHTFGHAIETEMGYGTWLHGEAIAAGCVLAARLSEQLGKTSAADTARLAALLEAAGLPSAPPVFAFEKWLEHMSHDKKVSGGIMRFIGLNRLGEANITEITDTDILRRTLQPYL
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: aroB mutant is attenuated in rats (Sun et al., 2000).
COG COG0337E, under E: Amino acid transport and metabolism
References
Sun et al., 2000: Sun YH, Bakshi S, Chalmers R, Tang CM. Functional genomics of Neisseria meningitidis pathogenesis. Nature medicine. 2000; 6(11); 1269-1273. [PubMed: 11062540].