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nadA from Neisseria meningitidis 053442

Victor ID 2916
Gene Name nadA from Neisseria meningitidis 053442
Sequence Strain (Species/Organism) Neisseria meningitidis 053442
NCBI Gene ID 5796858
NCBI Protein GI 161870678
Locus Tag NMCC_1750
Protein Accession YP_001599851.1
Other Database IDs UniProtKB-ID: NADA_NEIM0
UniRef100: UniRef100_A9M2J9
UniRef90: UniRef90_Q5F6I7
UniRef50: UniRef50_B2UAP5
UniParc: UPI00016108E2
EMBL: CP000381
EMBL-CDS: ABX73891.1
RefSeq_NT: NC_010120.1
EnsemblGenome: EBNEIG00000012473
EnsemblGenome_TRS: EBNEIT00000012473
EnsemblGenome_PRO: EBNEIP00000012015
GenomeReviews: CP000381_GR
KEGG: nmn:NMCC_1750
HOGENOM: HBG291157
OMA: IAHPECE
ProtClustDB: PRK09375
BioCyc: NMEN374833:NMCC_1750-MONOMER
Taxonomy ID 374833
Gene Starting Position 1798709
Gene Ending Position 1799821
Gene Strand (Orientation) +
Protein Name quinolinate synthetase A
DNA Sequence 
>gi|161869018:1798709-1799821 Neisseria meningitidis 053442, complete genome
CATGCAAACCGCCGCCCGCCGCTCGTTCGACTACGATATGCCACTCATCCAAACGCCGACTTCCGCCTGC
CAAATCCGTCAGGCGTGGGCGAAGGTTGCCGACACGCCCGACCGCGAGACGGCAGATCGTCTGAAAGACG
AAATCAAGGCTTTGCTGAAGGAGAAAAACGCGGTCTTGGTGGCGCATTATTATGTTGATCCGCTGATTCA
GGATTTGGCTTTGGAAACGGGCGGATGCGTGGGCGATTCTCTGGAAATGGCACGCTTCGGCGCGGAACAC
GAAGCCGGTACGCTGGTGGTGGCGGGCGTGCGTTTCATGGGAGAGAGCGCGAAAATCCTCTGCCCTGAAA
AAACGGTGCTGATGCCTGATTTGGAAGCGGAATGTTCTTTGGATTTGGGTTGCCCGGAAGAGGCGTTTTC
GGCGTTTTGCGACCAACACCCCGACCGCACGGTGGTGGTGTACGCCAACACTTCCGCCGCCGTGAAAGCG
CGTGCCGATTGGGTGGTAACGTCTTCGGTGGCGTTGGAAATCGTGTCGTATCTGAAATCGCGCGGCGAGA
AGCTGATTTGGGGGCCCGACCGCCACCTCGGCGACTACATCCGCCGCGAAACGGGCGCGGATATGCTGTT
GTGGCAGGGTTCGTGCATCGTCCACAACGAATTTAAAGGGCAGGAGCTGGCGGCGTTGAAGGCGGAACAC
CCCGATGCGGTGGTGCTGGTTCATCCCGAATCGCCACAAAGCGTCATCGAACTGGGCGACGTGGTCGGCT
CGACCAGCAAACTGCTGAAAGCTGCCGTATCACGCCCCGAAAAAAAATTCATCGTGGCGACCGATTTGGG
CATCCTGCACGAAATGCAAAAGCAGGCGCCCGACAAAGAATTTATCGCCGCGCCGACGGCGGGCAACGGC
GGAAGTTGCAAAAGCTGCGCGTTCTGCCCGTGGATGGCGATGAATTCGCTGGGCGGCATCAAATACGCCC
TGACAAGCGGACGTAACGAAATCCTGTTGGACAGGAAGCTGGGCGAAGCCGCCAAACTGCCTTTGCAGCG
TATGCTCGACTTCGCGGCAGGACTCAAACGCGGGGATGTGTTCAACGGCATGGGGCCCGCCTG
Protein Sequence 
>gi|161870678|ref|YP_001599851.1| quinolinate synthetase [Neisseria meningitidis 053442] MQTAARRSFDYDMPLIQTPTSACQIRQAWAKVADTPDRETADRLKDEIKALLKEKNAVLVAHYYVDPLIQDLALETGGCVGDSLEMARFGAEHEAGTLVVAGVRFMGESAKILCPEKTVLMPDLEAECSLDLGCPEEAFSAFCDQHPDRTVVVYANTSAAVKARADWVVTSSVALEIVSYLKSRGEKLIWGPDRHLGDYIRRETGADMLLWQGSCIVHNEFKGQELAALKAEHPDAVVLVHPESPQSVIELGDVVGSTSKLLKAAVSRPEKKFIVATDLGILHEMQKQAPDKEFIAAPTAGNGGSCKSCAFCPWMAMNSLGGIKYALTSGRNEILLDRKLGEAAKLPLQRMLDFAAGLKRGDVFNGMGPA
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: NadA mutation decreases epithelial adhesion of capsulate N. meningitidis and invasion by acapsulate N. meningitidis (Carbonnelle et al., 2009).
COG COG0379H, under H: Coenzyme transport and metabolism
References
Carbonnelle et al., 2009: Carbonnelle E, Hill DJ, Morand P, Griffiths NJ, Bourdoulous S, Murillo I, Nassif X, Virji M. Meningococcal interactions with the host. Vaccine. 2009; 27 Suppl 2; B78-89. [PubMed: 19481311].