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siaD

Victor ID 2915
Gene Name siaD
Sequence Strain (Species/Organism) Neisseria meningitidis 053442
NCBI Gene ID 5796762
NCBI Protein GI 161869086
Locus Tag NMCC_0075
Protein Accession YP_001598252.1
Other Database IDs UniProtKB-ID: A9LZW7_NEIM0
UniRef100: UniRef100_A1KR99
UniRef90: UniRef90_A1KR99
UniRef50: UniRef50_A1KR99
UniParc: UPI00016103E0
EMBL: CP000381
EMBL-CDS: ABX72299.1
RefSeq_NT: NC_010120.1
EnsemblGenome: EBNEIG00000012808.
EnsemblGenome_TRS: EBNEIT00000012808
EnsemblGenome_PRO: EBNEIP00000012350
GenomeReviews: CP000381_GR
KEGG: nmn:NMCC_0075
HOGENOM: HBG576828
OMA: IFNANEY
ProtClustDB: CLSK878416
BioCyc: NMEN374833:NMCC_0075-MONOMER
Taxonomy ID 374833
Gene Starting Position 72521
Gene Ending Position 73840
Gene Strand (Orientation) -
Protein Name alpha-2,8 polysialyltransferase
DNA Sequence 
>gi|161869018:72521-73840 Neisseria meningitidis 053442, complete genome
TTTATTGGTTACAAAGGCTATATTTAAAAAAATCATTTTTGATGTTTTGCCAAATCATTTTATCTTTATC
ATTAAAATATAAGGAAATTCTTTCAATGTAGTTAATTTCTAAATATTTCATTTTATAATTCTGCTTAACT
TTATTAAGGGCATTGTAATACCATAATGATTTATAGCCTAATACAGATAGATCATTATTACTGGCCAGTT
GCCAATAAAAAATTGCTTGGTAAAAGTTTTTGTTTTTATATGCATATTCAGCTGATTTTAGAAGCATTTC
TAATGTTTCTTCTGTCTTAAAAGAATTGGTGTCTATACCATCCTCTATACTTGATAATATTTTAATAAAA
TCGAATTGTTTAACAATCTCTAAATGCTCTTCAATTAAAGCGGTGTTCTCTTGTTGGGCTGTATGGTGTA
TCGAATCAATCACGATTTGCCCAATTGACAGACATTGGGTAGTAGGGGAAAGTAAAGGTGTATAAACAAT
AGAAGTCGATGTCAGTCCAATAATTCCTTTAGGGGTTGTTAAATAAATTAGTGGGTCAATGAGAAAAGGG
GGTTCATTAATCACTACTAGACGGGGATTAATTGTTACCATATTCAGGAATAAAGACATAATATTTTTAT
TCTCCATTTCTTTAGGATGGAGTTTAATAAAAATTTTACCTTCTATTCGCAAACTCATTTGATTTAATGT
TTCGACAATAGTTTTATAATAAACTTCATCTGAAACAGGATAGCGTTGACTTACAAAAATATAGTCATTT
TGAGATATGCGGTATTTGTCTTGAATTTTAGCAATAGATTGGCTTGTGCTAATCCCGCCTGAATGTGCAA
AAAAACGGTGGTATTCATTAGCATTGAAAATTTTTTTCGCATACTCAGGGAAAGCTACATGCAAAATATC
AAATTTATCAAAATAGCCTTTTTGATGTAAGTTGTTACCCACAAAACGTTGCTCAAATTTTGTGGGTTTG
TATGTAAATGATTCTAAGAGTGGGGCATAGGTTGCGGTTCCCTCTTCTACTAAATGTGTTGTGATATTCA
TTTTTTTTGCTAAGCTGAGCAGAGAGGAATAATGCCCAGCAAAAGACATAACATAAAGGTGTGCAGGTTG
GATAGTTTTGAGAAGCTTCTTATATCCACGCTGGATATATAGGAATTTTTTTGGGGAAACGATTCCCGGC
TTTCTTGGGAGTTCAAACATGTAAGTTACTGAAAATAATTCTTTATCAACTGATTTCTGAATTAATTTCG
GCATTTTCATATTTTGTGTGGTATATAAAATAACCAGTAAATTATTTTTTAATTTTTGCA
Protein Sequence 
>gi|161869086|ref|YP_001598252.1| alpha-2,8 polysialyltransferase [Neisseria meningitidis 053442] MQKLKNNLLVILYTTQNMKMPKLIQKSVDKELFSVTYMFELPRKPGIVSPKKFLYIQRGYKKLLKTIQPAHLYVMSFAGHYSSLLSLAKKMNITTHLVEEGTATYAPLLESFTYKPTKFEQRFVGNNLHQKGYFDKFDILHVAFPEYAKKIFNANEYHRFFAHSGGISTSQSIAKIQDKYRISQNDYIFVSQRYPVSDEVYYKTIVETLNQMSLRIEGKIFIKLHPKEMENKNIMSLFLNMVTINPRLVVINEPPFLIDPLIYLTTPKGIIGLTSTSIVYTPLLSPTTQCLSIGQIVIDSIHHTAQQENTALIEEHLEIVKQFDFIKILSSIEDGIDTNSFKTEETLEMLLKSAEYAYKNKNFYQAIFYWQLASNNDLSVLGYKSLWYYNALNKVKQNYKMKYLEINYIERISLYFNDKDKMIWQNIKNDFFKYSLCNQ
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: siaD mutant is attenuated in rats (Sun et al., 2000).
References
Sun et al., 2000: Sun YH, Bakshi S, Chalmers R, Tang CM. Functional genomics of Neisseria meningitidis pathogenesis. Nature medicine. 2000; 6(11); 1269-1273. [PubMed: 11062540].