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pilF from Neisseria meningitidis 053442

Victor ID 2902
Gene Name pilF from Neisseria meningitidis 053442
Sequence Strain (Species/Organism) Neisseria meningitidis 053442
NCBI Gene ID 5796169
NCBI Protein GI 161870741
Locus Tag NMCC_1814
Protein Accession YP_001599914.1
Other Database IDs UniProtKB-ID: A9M2Z2_NEIM0
UniRef100: UniRef100_A1KVV5
UniRef90: UniRef90_P37094
UniRef50: UniRef50_P37094
UniParc: UPI00000C4E0C
EMBL: CP000381
EMBL-CDS: ABX73954.1
RefSeq_NT: NC_010120.1
EnsemblGenome: EBNEIG00000011950.
EnsemblGenome_TRS: EBNEIT00000011950
EnsemblGenome_PRO: EBNEIP00000011492
GenomeReviews: CP000381_GR
KEGG: nmn:NMCC_1814
HOGENOM: HBG485518
OMA: PLGRREN
ProtClustDB: CLSK877498
BioCyc: NMEN374833:NMCC_1814-MONOMER
Taxonomy ID 374833
Gene Starting Position 1859740
Gene Ending Position 1861416
Gene Strand (Orientation) -
Protein Name type IV pilus assembly protein
DNA Sequence 
>gi|161869018:1859740-1861416 Neisseria meningitidis 053442, complete genome
CCTAATCGTTGGTATTTGCCGTTACCTCTTCCAATGAAGTAATGCCCTGCATAACTTTCAAAATACCGGC
CCGGCGCAAATCCACCATACCCTCCTTATAGGCAACGTCCAAAATATCCACTTCCGTACCGTTGTTCATA
ATCACACGCTGCATTTCTTCGCTGATGGGCATAACCTCATACACGCCCGCACGCCCCTTATAACCCTGTC
CCCGGCAACGGTCGCAACCGACGGCGCGGTAAAGTTTCCAATCTTTTGCAAGGTCCTCATCGGTGAAGCC
GACTTCCTTCAAAGCAGAGGCAGACGGGCGTTCCACTTCCTGTTTGCAGCTCGAACACAGCCTGCGTAAA
AGACGCTGCGCCATAATCAGGCTGACCGAACTGGCAATATTAAACGGCGCGACACCCATATTCAGCATAC
GCGACAACGTCGCCGGCGCATTATTCGTGTGCAGTGTGGAAAACACCATATGCCCTGTTTGTGCCGCCTT
AATCGCAATATCGGCAGTTTCCAAATCACGAATCTCACCGACCATAATGATGTCCGGGTCCTGACGCAGG
AAAGACTTCAAAGCAGCGGCAAAAGTCAGGCCCTGCTTATCATTGACGTTAACCTGATTGATGCCCGGCA
GGTTAATCTCGGCAGGGTCTTCCGCCGTTGCAATATTTACCGACTCCGTATTCAAAATATTCAAACAGGT
ATAGAGCGACACCGTCTTACCCGAACCCGTCGGACCGGTTACCAGCACCATCCCGTAGGGACGGTGAATC
GCTTCCAACAACAATTTTTTCTGAAACGGCTCAAAACCGAGCTGGTCGATGTTCAAAGACGCGGCATCGG
AATTCAAAATCCGCATCACGACCTTTTCGCCAAACAGCGTCGGCAATGTGCTGACACGGAAATCGACAGG
CTTGCCGCCCTTTTGAAAGGTCAGCTGCATCCTGCCGTCCTGCGGTATCCGTTTTTCGGAAATGTCCAAA
CGCGACATTACCTTAATCCGGGAAGCAAGCTGCCCCCTTACCGCAATGGGCGGCTGAACCACCTCGCGGA
GCTGCCCGTCCACACGGAAACGGATACGGGCATTGTGTTCGTAAAACTCGAAATGGATGTCCGATGCCCC
GCTGCGCAAGGCATCCGACAAAGTCTTATGGATAAACCTCGGAACAGGGCCGTCTTCTGCCTCCTCGTTG
TCGATATACAGGGTGTGGCTTTCCTCTTCCTCCTGCCCCTCCCCAAGCTCCTGAAGCAGCGATGTCGAAC
GCGAACCCACCCAATCGAGCAAACCCGCCAACTGGTCATCCTCGACAATGACCAACTCAACCTCAATCCC
TGCGGCAGAAACGGTTTTCTGAATTTGCGGCATCTGTGTCGGATCGGAAACCGCAAAAAATACTTTGTCG
CCCCGACGGAAAACCGGCACACAGTGGAACTCCACCATCTGCTCCTCCGTCAACACCCCCATCAGCACCC
TGTGGCGCGGATAATGACGCAAATCAAGAATCGAATAACTGAACACCCTCGCAATCAATGCCGCAAGCGA
CTTGGGCGAAATGACACCGTCTGAAAACAGCATCGGCAACACTTCCTTACCCGCCTGCGACTCATTGTAG
TAATGCTCGGCCTGCTCAACAGTAACCACCTGGTTTTGAACCAGAATCCTCAGCAAACCTACGCTCA
Protein Sequence 
>gi|161870741|ref|YP_001599914.1| type IV pilus assembly protein [Neisseria meningitidis 053442] MSVGLLRILVQNQVVTVEQAEHYYNESQAGKEVLPMLFSDGVISPKSLAALIARVFSYSILDLRHYPRHRVLMGVLTEEQMVEFHCVPVFRRGDKVFFAVSDPTQMPQIQKTVSAAGIEVELVIVEDDQLAGLLDWVGSRSTSLLQELGEGQEEEESHTLYIDNEEAEDGPVPRFIHKTLSDALRSGASDIHFEFYEHNARIRFRVDGQLREVVQPPIAVRGQLASRIKVMSRLDISEKRIPQDGRMQLTFQKGGKPVDFRVSTLPTLFGEKVVMRILNSDAASLNIDQLGFEPFQKKLLLEAIHRPYGMVLVTGPTGSGKTVSLYTCLNILNTESVNIATAEDPAEINLPGINQVNVNDKQGLTFAAALKSFLRQDPDIIMVGEIRDLETADIAIKAAQTGHMVFSTLHTNNAPATLSRMLNMGVAPFNIASSVSLIMAQRLLRRLCSSCKQEVERPSASALKEVGFTDEDLAKDWKLYRAVGCDRCRGQGYKGRAGVYEVMPISEEMQRVIMNNGTEVDILDVAYKEGMVDLRRAGILKVMQGITSLEEVTANTND
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: pilF mutant were unable to colonize human nasopharyngeal tissue in an organ culture model (Exley et al., 2009).
COG COG2804NU, under N: Cell motility; U: Intracellular trafficking, secretion, and vesicular transport
References
Exley et al., 2009: Exley RM, Sim R, Goodwin L, Winterbotham M, Schneider MC, Read RC, Tang CM. Identification of meningococcal genes necessary for colonization of human upper airway tissue. Infection and immunity. 2009; 77(1); 45-51. [PubMed: 18936183].