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ilvD from Neisseria meningitidis 053442

Victor ID 2898
Gene Name ilvD from Neisseria meningitidis 053442
Sequence Strain (Species/Organism) Neisseria meningitidis 053442
NCBI Gene ID 5796004
NCBI Protein GI 161870035
Locus Tag NMCC_1068
Protein Accession YP_001599204.1
Other Database IDs UniProtKB-ID: A9LZ71_NEIM0
UniRef100: UniRef100_A9LZ71
UniRef90: UniRef90_A9LZ71
UniRef50: UniRef50_Q5F8G6
UniParc: UPI00016106EC
EMBL: CP000381
EMBL-CDS: ABX73248.1
RefSeq_NT: NC_010120.1
EnsemblGenome: EBNEIG00000011848.
EnsemblGenome_TRS: EBNEIT00000011848
EnsemblGenome_PRO: EBNEIP00000011390
GenomeReviews: CP000381_GR
KEGG: nmn:NMCC_1068
HOGENOM: HBG671001
OMA: SRKVPCL
ProtClustDB: PRK12448
BioCyc: NMEN374833:NMCC_1068-MONOMER
Taxonomy ID 374833
Gene Starting Position 1047854
Gene Ending Position 1049941
Gene Strand (Orientation) -
Protein Name dihydroxy-acid dehydratase
DNA Sequence 
>gi|161869018:1047854-1049941 Neisseria meningitidis 053442, complete genome
CTTATCTTTCGATTTGCGCTACGTCGCGCACCGCGCCTTTGTCGGCGGAAGTCGCCATCGCGCCGTAAGC
TCTTAATGCGGCGGAGACGTAGCGGTCGCGGTTTTTAGGCTTCCATGCTTTGCTGCCGCGCGCTTCCATT
TCGGCACGGCGTGCGGCAAGCTCTTCATCGGAAATGGCAAGGTGGATGCTGCGGTTGGGGATGTCGATTT
CGACGGTATCGCCTTCGTGTACCAAACCGATCGCGCCACCTTCCGCCGCTTCGGGCGAGGCGTGTCCGAT
GGACAAACCTGATGTGCCGCCGGAGAAGCGTCCGTCGGTTAAGAGAGCGCAGGCTTTGCCGAGGCCTTTA
GATTTCAGGTAGGAAGTCGGATACAGCATTTCCTGCATGCCCGGGCCGCCTTTCGGGCCTTCGTAGCGGA
TGATGACGATGTCGCCGGCGACGATTTGGTTGCCCAAAATGCCTTCTACTGCGTCTTCTTGGCTTTCAAA
CACGCGGGCGCGGCCGGTGAATTTGAGGATGCTCTCATCCACGCCTGCGGTTTTTACCACGCAGCCGCGT
TCGGCGATGTTGCCGAACAAGACCGCCAAACCGCCGTCTTGCGAGTAGGCGTGTGCCACGTCGCGGATAC
AGCCTTTTTCGCGGTCGAGGTCGAGGGTTTTCCACATACGGTTTTGCGAGAACGCTTGGGTGGTACGTAC
GCCGCCGGGCGCGGCTTTGAAGCGTTCGATGGCGCGGGTGTTTTCAGGGTTGGTTACGTCCCATTTTTCA
ATCGCGTCTTTCAGCGTCGGTGCGTGGATAGTGTGCACGTCGGTGTGCAGTTTGCCCGCTTTGTCCAATT
CTTTCAGGATGGCGAAGATGCCGCCGGCTCGGTGCACGTCTTCCATATAGTAGTCGTGGTTGTTGGGCGC
GGTTTTGCAGATGCAGGGCACGACGCGGCTTAAGCGGTCGATGTCGGCCATTTTGAAATCCACGCCCGCT
TCGTTGGCGACGGCGAGCAAATGCAGGATGGTGTTGGTAGAGCCGCCCATCGCAATGTCCATCGTCATAG
CGTTTTCAAACGCTTTTTTGGTGGCGATGCTGCGCGGCAGTACGGTTTCGTCGTCTTGCTCGTAATAGCG
TTTGGTGATTTCGACAATCATACGGCCTGCTTCGAGGAACAATTCTTTGCGGCCGGCGTGGGTCGCCAAA
TACGAACCGTTGCCGGGCAGGGAAAGGCCGAGTGCTTCGGTCAGGCAGTTCATCGAGTTTGCCGTAAACA
TACCCGAACACGAGCCGCAGGTCGGGCAGGCGTTTTGTTCGACTTCTTCGACTTGCCGGTTGCTGACATT
GTCGTCTGCCGATTCGATCATCGCGTCAATCAAGTCCAAACGGCGTTCGGGTTGGATGTTTGCCACGCCG
ATAACTTTACCTGCTTCCATCGGGCCGCCGGAGACGAAGATGGTGGGGATGTTCAGGCGCATCGCGGCAA
TCAGCATGCCCGGGGTGATTTTGTCGCAGTTGGAAATGCACACCAGCGCGTCGGCGCAGTGGGCGTTGAC
CATATATTCGATAGAGTCGGCAATCAAATCGCGGCTGGGCAGGGAGTACAGCATGCCGCTGTGTCCCATA
GCGATGCCGTCGTCGATGGCGATGGTGTTGAATTCTTTGGCGATTGCGCCGGCTTTTTCGATTTCGCGGG
CAACCAGCTGGCCCATATTGTGCAGGTGGACATGGCCGGGCACGAATTGGGTGAAGGAGTTGGCAACGGC
GATGATGGGCTTGCCGAAGTCGGTTTCCATCACGCCGGTCGCACGCCACAATGCGCGTGCGCCTGCCATA
TTGCGGCCGTGGGTAGAGGTTTTGGAGCGGTATTCTGGCATAGTGTGTTTCCTTGTGCCTATACCGTCTG
AAAGACAGGGCTGTTTCAGACGGTATCGGGTACGGTTTTTTAGAGTGGGAAAAGAGGGTATTTTATACCA
AGTATCGGAATTTTGCGGGATTGAAACGGCGTGCGGCAAAAAAGAAAATCCCCGCAGGAATGCGGGGACG
GGTTCAGGCGCGGGCAATCGCGACGGCTTTGGATACGTCCCAAAAATCAACGGGTGCA
Protein Sequence 
>gi|161870035|ref|YP_001599204.1| dihydroxy-acid dehydratase [Neisseria meningitidis 053442] MHPLIFGTYPKPSRLPAPEPVPAFLRGFSFLPHAVSIPQNSDTWYKIPSFPTLKNRTRYRLKQPCLSDGIGTRKHTMPEYRSKTSTHGRNMAGARALWRATGVMETDFGKPIIAVANSFTQFVPGHVHLHNMGQLVAREIEKAGAIAKEFNTIAIDDGIAMGHSGMLYSLPSRDLIADSIEYMVNAHCADALVCISNCDKITPGMLIAAMRLNIPTIFVSGGPMEAGKVIGVANIQPERRLDLIDAMIESADDNVSNRQVEEVEQNACPTCGSCSGMFTANSMNCLTEALGLSLPGNGSYLATHAGRKELFLEAGRMIVEITKRYYEQDDETVLPRSIATKKAFENAMTMDIAMGGSTNTILHLLAVANEAGVDFKMADIDRLSRVVPCICKTAPNNHDYYMEDVHRAGGIFAILKELDKAGKLHTDVHTIHAPTLKDAIEKWDVTNPENTRAIERFKAAPGGVRTTQAFSQNRMWKTLDLDREKGCIRDVAHAYSQDGGLAVLFGNIAERGCVVKTAGVDESILKFTGRARVFESQEDAVEGILGNQIVAGDIVIIRYEGPKGGPGMQEMLYPTSYLKSKGLGKACALLTDGRFSGGTSGLSIGHASPEAAEGGAIGLVHEGDTVEIDIPNRSIHLAISDEELAARRAEMEARGSKAWKPKNRDRYVSAALRAYGAMATSADKGAVRDVAQIER
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: ilvD mutant is attenuated in rats (Sun et al., 2000).
COG COG0129EG, under E: Amino acid transport and metabolism; G: Carbohydrate transport and metabolism
References
Sun et al., 2000: Sun YH, Bakshi S, Chalmers R, Tang CM. Functional genomics of Neisseria meningitidis pathogenesis. Nature medicine. 2000; 6(11); 1269-1273. [PubMed: 11062540].