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pilQ from Neisseria meningitidis 053442

Victor ID 2895
Gene Name pilQ from Neisseria meningitidis 053442
Sequence Strain (Species/Organism) Neisseria meningitidis 053442
NCBI Gene ID 5795870
NCBI Protein GI 161869408
Locus Tag NMCC_0416
Protein Accession YP_001598575.1
Other Database IDs UniProtKB-ID: A9M1U6_NEIM0
UniRef100: UniRef100_Q9JVW4
UniRef90: UniRef90_Q70M91
UniRef50: UniRef50_Q5FAD2
UniParc: UPI00000C4A06
EMBL: CP000381
EMBL-CDS: ABX72621.1
RefSeq_NT: NC_010120.1
EnsemblGenome: EBNEIG00000011009.
EnsemblGenome_TRS: EBNEIT00000011009
EnsemblGenome_PRO: EBNEIP00000010551
GenomeReviews: CP000381_GR
KEGG: nmn:NMCC_0416
HOGENOM: HBG482665
OMA: QNVPWDQ
ProtClustDB: CLSK878435
BioCyc: NMEN374833:NMCC_0416-MONOMER
Taxonomy ID 374833
Gene Starting Position 429525
Gene Ending Position 431810
Gene Strand (Orientation) -
Protein Name type IV pilus assembly protein PilQ
DNA Sequence 
>gi|161869018:429525-431810 Neisseria meningitidis 053442, complete genome
ATCAATAGCGCAGGCTGTTGCCGGCCGTACCCATAATCCTCGGGGTAATGAAAATCAGCAGTTCGCGGCG
GTCGGTTTTTTTCCCGCGTGTTTTAAAGAGGTTGCCGATAACGGGGATGTCGCCCAACAGGGGGACTTTG
GTCAGCGTATTACCGTTGTCTTCTTCATAAATACCGCCGACAATCAATGTGCCGCCGTTTTCAACCATAG
CCTGCGTATTCAGGTTTTTGGTCGAAATACACAGAATCGTCTGATTACCGGAGGCACATTGCGCAGGCGA
GTCCTTGTTGATTTTGACGGTCATAATGATTTGGCCGTCGGGCGTGATGTTCGGCGTAACGGTCAGCCCC
AAGACGGCTTTTTTGAGTTCCGTGTTCGTGCTGCTGCCGCCGTTCGCGATTGAGGTTACGGTGAAAGGAA
TTTCGTAACCAGATTCGATTTTGGCCTCTTTGCGGTTTTGGGTCAGCACGCGCGGATTGGCAAGCGTTTT
GGTTTTTGAAAGCGATTCGGATGCGGACAATTCCAAATTCAAGGCACCGGAGGAAATCGCGCGCACCAGC
GAAATGCTGTTTGCGGCAGCGGTAATCGGCAGGTTGATTTTGGTTTCGGCCCCCCATTTATCGTCGCCGC
CGAAGCCGGAGTTTACCCCCCAGCCGAATGCGCTTGTATCATTTTTCAGCTTTTTCTTGCCTGTCGCGCC
GAATTTAACGCCCAAATCGCGCGAGAAGCCGTCTGCCGCTTCGACGATACGCGCCTCAATCATCACTTGT
TGCGCGGGTACGTCCAATTCGTCAATCAGTTTGCGGAATTTTTCGATGACGCTGCGGGTATCGGTAACAA
TCAGGGTATTGGTGGCGGGATCGATCAGCACGCTGCCCCTGCCGCTGACAAGCGTATTGCGGTTTCCGGT
TGTGTCGGCATTGTCCAAACGCAGGATGCTGCGGAATTCTTCCACATTTTTGTATTTCAATTGGAAGTTT
TGTGAATACAGCGCGCCCAGATCGGCAATGTCTTTTTCCGCCTGTAAGAAGGCTTTGTCTTTGGCAAGCA
GCTCGTCGCGGGGCGCGATGTTGACGATGTTCCCTTGCTGGCGCATATCGAGGTTGCGTGCCTGCATAAC
CAAATCCAAAGCCTGATCCCAAGGTACGTCTTTGAGGGAGAGGGTCATTTTGCCGTTGACGGAGTCGCTG
GCAACAATGTTCATCCCGGATTCTTTTGCCAAAATCTGCAGGATGGTGCGGATTTCGACATCTTGGAAGT
CAAGGGAGATTTTCCGGCCTGTGAAGGTTTTGGGCGCATTGTTCACGCCGCCTGACTCGAGGTTTTGTTT
TTTCGGCAGGACTTGGAAGGTAAAGTATCCGGGCGCGGCGGATTTGTTGACGAGTTCCCAGTTGCCGGCT
GTTGTGATAATCAGCTGGGTGTCGTTATTGAGGCGTTTCAGCGTAACCTTTTGAACCGGTGTTTTAAAGT
CTGCCACATCCAAACTGCGTTGGAGCGTGGTCGGCAGGGTATGGTTTTTCAGCGTAACGATGATGTGGTC
GTGCTGTTGGCTGATGTCGGGCTGCCCGGCAAAGCCCAATGCAGCCAATTCGATAATGCCGGCATTTTTG
CCGTCTTTGCGGAAATCGATATTGGTTTGTTTTGCTGGTGTTGCCGCCTGTTGTTTTGCTGGTGCTGCCG
TCTGTTGTTTTGCTGATGCCGCCGCCTGTTGTTTTGCCGGGCTGAACGGTGCGGATACGGATACTACGGA
CTCGGTAAACGGTGCGGCAGCCTGTTGTTTTGCCGGGGTAAAGGGTTTGGATACGGATACTGCGGACTTG
GTAGACGGTGCGGCAGCCTGTTGTTTTGCCGGTGCGGCAGGCGCGGCTTTTACGGCGGGGCGTGCGGGGG
CGGACACGGTATCGTCCGATTCGTTAATGAATATCCAAACTTTGTTCCCGCGTACTTCGGTATTGTATTG
GCCCGGTTTGTTCAGATTCAGAACCAAACGCGCACGGCTGCTGTTTTGTGCGGCACTGATTTTGCTCAAC
AGGGGATCGGCATATTCGAGTACCTGTTGATCCATGGAAATGCCGGTTTGTTCAAAGTCCAAGGCGATGC
GGGCCGGTGAGGAGGTTACGAAGCCGGTCGGGTTGACAATCTCTTTGTCAAAGCTGACTTTGACGATTTT
CTGTTTGTTGGGCAGGGAGGAAACTTTGATGTCTGTAATGTTTCCTGCCGATGCTGTCTGAAAGGCGGCG
GTTGCGACAAAGAGACCGGAAATGATTTTTGTCAGTTTGGTATTCA
Protein Sequence 
>gi|161869408|ref|YP_001598575.1| type IV pilus assembly protein PilQ [Neisseria meningitidis 053442] MNTKLTKIISGLFVATAAFQTASAGNITDIKVSSLPNKQKIVKVSFDKEIVNPTGFVTSSPARIALDFEQTGISMDQQVLEYADPLLSKISAAQNSSRARLVLNLNKPGQYNTEVRGNKVWIFINESDDTVSAPARPAVKAAPAAPAKQQAAAPSTKSAVSVSKPFTPAKQQAAAPFTESVVSVSAPFSPAKQQAAASAKQQTAAPAKQQAATPAKQTNIDFRKDGKNAGIIELAALGFAGQPDISQQHDHIIVTLKNHTLPTTLQRSLDVADFKTPVQKVTLKRLNNDTQLIITTAGNWELVNKSAAPGYFTFQVLPKKQNLESGGVNNAPKTFTGRKISLDFQDVEIRTILQILAKESGMNIVASDSVNGKMTLSLKDVPWDQALDLVMQARNLDMRQQGNIVNIAPRDELLAKDKAFLQAEKDIADLGALYSQNFQLKYKNVEEFRSILRLDNADTTGNRNTLVSGRGSVLIDPATNTLIVTDTRSVIEKFRKLIDELDVPAQQVMIEARIVEAADGFSRDLGVKFGATGKKKLKNDTSAFGWGVNSGFGGDDKWGAETKINLPITAAANSISLVRAISSGALNLELSASESLSKTKTLANPRVLTQNRKEAKIESGYEIPFTVTSIANGGSSTNTELKKAVLGLTVTPNITPDGQIIMTVKINKDSPAQCASGNQTILCISTKNLNTQAMVENGGTLIVGGIYEEDNGNTLTKVPLLGDIPVIGNLFKTRGKKTDRRELLIFITPRIMGTAGNSLRY
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: pilQ mutant were unable to colonize human nasopharyngeal tissue in an organ culture model (Exley et al., 2009).
COG COG4796U, under U: Intracellular trafficking, secretion, and vesicular transport
References
Exley et al., 2009: Exley RM, Sim R, Goodwin L, Winterbotham M, Schneider MC, Read RC, Tang CM. Identification of meningococcal genes necessary for colonization of human upper airway tissue. Infection and immunity. 2009; 77(1); 45-51. [PubMed: 18936183].