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aroB from Neisseria meningitidis 053442

Victor ID 2892
Gene Name aroB from Neisseria meningitidis 053442
Sequence Strain (Species/Organism) Neisseria meningitidis 053442
NCBI Gene ID 5795648
NCBI Protein GI 161869406
Locus Tag NMCC_0414
Protein Accession YP_001598573.1
Other Database IDs UniProtKB-ID: AROB_NEIM0
UniRef100: UniRef100_A9M1U4
UniRef90: UniRef90_Q5FAD4
UniRef50: UniRef50_A5CX62
UniParc: UPI00016103FF
EMBL: CP000381
EMBL-CDS: ABX72619.1
RefSeq_NT: NC_010120.1
EnsemblGenome: EBNEIG00000011147
EnsemblGenome_TRS: EBNEIT00000011147
EnsemblGenome_PRO: EBNEIP00000010689
GenomeReviews: CP000381_GR
KEGG: nmn:NMCC_0414
HOGENOM: HBG632303
OMA: CEIKAEV
ProtClustDB: PRK00002
BioCyc: NMEN374833:NMCC_0414-MONOMER
Taxonomy ID 374833
Gene Starting Position 426676
Gene Ending Position 427755
Gene Strand (Orientation) -
Protein Name 3-dehydroquinate synthase
DNA Sequence 
>gi|161869018:426676-427755 Neisseria meningitidis 053442, complete genome
ATCAGAGATACGGTTGCAGGGTGCGGCGGAGAATGTCCGTGTCGGTAATTTCGGTGATGACGGCTTCGCC
CAGACGGTTCAACCCGATAAAGCGCATCACGCCGCTACTGACTTTTTTATCGTGGCTCATGTGTTCCAGC
CATTTTTCAAAGGCAAACACGGGTGGCGCGGACGGCAGTCCGGCGGCTTCGAGCAGGGCGGCGAGCCGCG
CGGTATCTGCGGCGGAGATTTTGCCCAGTTGTTCGGACAAACGCGCCGCCAACACGCAGCCGGCGGCGAC
GGCCTCGCCGTGCAGCCAAGTACCGTAACCCATCTCGGTTTCAATGGCGTGTCCGAAGGTGTGTCCGAGG
TTGAGCCATGCGCGTATGCCCTGTTCGGTTTCGTCTTGGGCGACGATGTCTGCCTTCATTTGGCAACAGC
GGTACACGGCTTGGATGAGGGGCGCGCGTTCGAGTGCCATCAGTTCGGGCATATGCTGTTCCAGCCATTC
AAAAAAACTAATGTCGCCGAGCGTGCCGTATTTGATGACTTCCGCCATACCGGCGGACAGTTCGCGGGCG
GGCAGGGTGTGCAGCGTGTCCAAGTCGGCAAGCACCGCCTGCGGCTGGTAGAACGCGCCGATCATATTTT
TGCCGAGCGGGTGGTTGATGGCGGTTTTGCCGCCGACGGAGGAATCGACCTGACTTAATAAAGTAGTGGG
AATTTGAACAAATGGCGCGCCGCGTTGATAAGTAGCCGCCGCAAAACCCGTCATATCGCCGATCACGCCG
CCGCCCAGTGCGATGAGCGTGGTTTTGCGTTCGGCGCGGTTTTGCATCAGCCCGTCAAAGATGAGGTTGA
GCGTCTGCCAGTTTTTGTGCGCCTCGCCGTCGGGCAGGATGATGCTGAAATGGGATACGCCTGCCGCATC
CAATGCCGTCTGAAGCGTGCCGAGGTAGAGCGGGGCGACGGTTTCGTTGGTGATGATGGCGGCGCGTTTG
CCCAAATGCGGTTTGAGCAGGCTTCCTGCCTGCGGCAGCAGTCCGTTGCCGATAAAGATGGGGTAGCTGT
GGGACGGGGTGTGTACGGTCAGTGTTTTCA
Protein Sequence 
>gi|161869406|ref|YP_001598573.1| 3-dehydroquinate synthase [Neisseria meningitidis 053442] MKTLTVHTPSHSYPIFIGNGLLPQAGSLLKPHLGKRAAIITNETVAPLYLGTLQTALDAAGVSHFSIILPDGEAHKNWQTLNLIFDGLMQNRAERKTTLIALGGGVIGDMTGFAAATYQRGAPFVQIPTTLLSQVDSSVGGKTAINHPLGKNMIGAFYQPQAVLADLDTLHTLPARELSAGMAEVIKYGTLGDISFFEWLEQHMPELMALERAPLIQAVYRCCQMKADIVAQDETEQGIRAWLNLGHTFGHAIETEMGYGTWLHGEAVAAGCVLAARLSEQLGKISAADTARLAALLEAAGLPSAPPVFAFEKWLEHMSHDKKVSSGVMRFIGLNRLGEAVITEITDTDILRRTLQPYL
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: aroB mutant is attenuated in rats (Sun et al., 2000).
COG COG0337E, under E: Amino acid transport and metabolism
References
Sun et al., 2000: Sun YH, Bakshi S, Chalmers R, Tang CM. Functional genomics of Neisseria meningitidis pathogenesis. Nature medicine. 2000; 6(11); 1269-1273. [PubMed: 11062540].